Spindle Cell Type Gastrointestinal Stromal Tumor

2020 ◽  
Author(s):  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Spindle Cell ◽  
Stromal Tumor ◽  
Cell Type ◽  
Spindle Cell Type

A case of spindle cell type carcinoid tumor of the duodenum had been difficult to discriminate with the gastrointestinal stromal tumor

2014 ◽  
Vol 53 (5) ◽  
pp. 383-389
Author(s):  
Hiroko HINO ◽  
Sakae HATA ◽  
Hirohisa TAKASUGA ◽  
Mari NARITOMI ◽  
Yasumasa MONOBE
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Carcinoid Tumor ◽  
Spindle Cell ◽  
Stromal Tumor ◽  
Cell Type ◽  
Spindle Cell Type

scholarly journals Platelet-Derived Growth Factor Receptor-Alpha D842v Mutation in a Spindle Cell Type Gastrointestinal Stromal Tumor: A Case Report

2018 ◽  
Vol 3 (1) ◽  
pp. 16-19
Author(s):  
Jenissa Amor Arceño ◽  
◽  
Kathleen Chua ◽  
Loraine Kay Cabral ◽  
Arlie Jean Dumasis ◽  
...  
Keyword(s):  
Case Report ◽  
Growth Factor ◽  
Gastrointestinal Stromal Tumor ◽  
Spindle Cell ◽  
Growth Factor Receptor ◽  
Platelet Derived Growth Factor ◽  
Cell Type ◽  
Receptor Alpha ◽  
Factor Receptor Alpha ◽  
Spindle Cell Type

scholarly journals Gastrointestinal Stromal Tumor of the Ampulla of Vater: A Narrative Review

2021 ◽  
pp. 1-6
Author(s):  
Bita Geramizadeh ◽  
Alireza Shojazadeh
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Spindle Cell ◽  
English Literature ◽  
Ampulla Of Vater ◽  
Good Prognosis ◽  
Stromal Tumor ◽  
Treatment Modalities ◽  
Histologic Diagnosis ◽  
Lower Gi Bleeding ◽  
Mitotic Figures

<b><i>Background:</i></b> Gastrointestinal stromal tumor (GIST) of the ampulla of Vater is a rare occurrence. To the best of our knowledge, there has been no published review on this rare tumor in the English literature so far. <b><i>Summary:</i></b> In this review, we will discuss all the reported details of the published cases, including demography, clinical presentation, imaging, gross pathology and histopathology, immunohistochemical findings, treatment modalities, and outcome of cases with the diagnosis GIST from the ampulla of Vater in the last 20 years. <b><i>Key Message:</i></b> Twenty-five cases of GIST in the ampulla of Vater have been reported in the last 20 years in the English literature. GIST in the ampulla of Vater are usually small tumors (&#x3c;5 cm) in middle-age patients. The majority of the patients present with lower GI bleeding and abdominal pain. Imaging findings are not characteristic, and most of the patients without biopsy and with no histologic diagnosis were operated with the primary impression of adenocarcinoma, neuroendocrine tumor, and GIST. Perioperative tissue biopsy has been accurate in &#x3c;70% of the cases. The majority of the reported cases of GISTs in the ampulla of Vater have been low risk with spindle-cell morphology, low mitotic figures, and minimal atypia; reactive for C-KIT and DOG-1; and nonreactive for SMA, desmin, and S100. In the majority of the cases, duodenectomy with or without Whipple’s operation has been performed, and most of the cases showed good prognosis.

A case of spindle cell type anaplastic carcinoma of the pancreas presented rapidly aggressive liver metastasis

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S120
Author(s):  
Yu Nobuoka ◽  
Taijiro Takeuchi ◽  
Hiroyuki Yuasa ◽  
Kanji Tanigawa ◽  
Hajime Yokoi
Keyword(s):  
Liver Metastasis ◽  
Spindle Cell ◽  
Anaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Pancreas ◽  
Spindle Cell Type

scholarly journals Cytokeratin-positive interstitial reticulum cell (CIRC) tumor in the lymph node: a case report of the transformation from the epithelioid cell type to the spindle cell type

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Sachiko Kaji ◽  
Nobuyuki Hiruta ◽  
Daisuke Sasai ◽  
Makoto Nagashima ◽  
Rintaro Ohe ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Lung Carcinoma ◽  
Spindle Cell ◽  
Small Cell Lung Carcinoma ◽  
Epithelioid Cell ◽  
Small Cell ◽  
Cell Type ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma ◽  
Spindle Cell Type

Abstract Background Cytokeratin-positive interstitial reticulum cells (CIRCs), which are a subgroup of fibroblastic reticular cells (FRCs), are known to be present in the lymph nodes. There have been only a few cases of tumors derived from CIRCs. Case presentation We have reported a new case involving a CIRC tumor in a 75-year-old man and reviewed the literature. The resected mediastinal lymph nodes showed epithelial-like proliferation of large atypical round and polygonal epithelioid cells. The tumor cells expressed CK8, CK18, CAM5.2, AE1/AE3, epithelial membrane antigen, vimentin, fascin, and some FRC markers, which is consistent with the diagnosis of a CIRC tumor. Following chemotherapy, the CIRC tumor was observed to have responded very well and became difficult to confirm on imaging, but a small cell lung carcinoma developed 12 months later. Chemoradiotherapy was performed, but the patient passed away 29 months after the initial diagnosis. The autopsy revealed the recurrence of the CIRC tumor, residual small cell lung carcinoma, and a very small latent carcinoma of the prostate. The relapsed CIRC tumor cells had a spindle shape; they were highly pleomorphic and had invaded the superior vena cava. Conclusion We first reported autopsy findings of CIRC tumors and demonstrated the transformation of the tumor from the epithelioid cell type to the spindle cell type.

scholarly journals A case of spindle cell type anaplastic carcinoma of the pancreas which developed acute pancreatitis

Suizo ◽  
2016 ◽  
Vol 31 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Yousuke MICHIKAWA ◽  
Kazunari NAKAHARA ◽  
Keigo SUETANI ◽  
Ryo MORITA ◽  
Sarika KITAGAWA ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Spindle Cell ◽  
Anaplastic Carcinoma ◽  
Cell Type ◽  
Carcinoma Of The Pancreas ◽  
Spindle Cell Type
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