scholarly journals A Comparison of Early Enteral Nutrition and Total Parenteral Nutrition after Total Gastrectomy

2007 ◽  
Vol 24 (4) ◽  
pp. 1-10
Author(s):  
권희 ◽  
안지현 ◽  
이은주 ◽  
조미화 ◽  
강정애 ◽  
...  
2021 ◽  
Author(s):  
Jianbo Song ◽  
xiaoguang Lu ◽  
Libin Zhan ◽  
Xin Kang ◽  
Yilong Zhong ◽  
...  

Abstract Background The mechanism of early enteral nutrition on intestinal mucosal barrier is still not fully understood and the direct evidence to demonstrate the protective effects of early enteral nutrition against remote organs injury induced by severe acute pancreatitis is lacking. Methods Rats were randomly divided into three groups: 1) only flip pancreas and free diet (n = 8); 2) severe acute pancreatitis and total parenteral nutrition (n = 15); 3) severe acute pancreatitis and early enteral nutrition (n = 15). Severe acute pancreatitis was induced by the retrograde injection of pancreaticobiliary duct with sodium taurocholate. Nutritional supplementation was administered starting 12 hours after induction of pancreatitis. The samples were obtained after the treatment of nutrition 72 hours. Results The mortality was not significant difference between the experimental groups. The pathology of ileum and the content of serum diamine oxidase were significantly lower in early enteral nutrition group than total parenteral nutrition group. The expression of tight junction ZO-1, Occludin and Claudin-1 proteins and the intraepithelial CD8+ and TCRγδ+ lymphocytes were significantly higher in early enteral nutrition group than total parenteral nutrition group. The content of the serum amylase and endotoxin were significantly lower in early enteral nutrition group than total parenteral nutrition group. There was a tendency of decreased pancreas and lung pathology scores in early enteral nutrition group, but the difference between total parenteral nutrition and early enteral nutrition groups was not significant. Conclusion The early enteral nutrition could significantly improve the expression of the tight junctions and intraepithelial lymphocytes, accompanied by improved intestinal mucosal barrier and endotoxin, but failed to the pancreas and lung injury compared to total parenteral nutrition in the rat model of severe acute pancreatitis.


2017 ◽  
Vol 145 (7-8) ◽  
pp. 411-414
Author(s):  
Marina Panisic-Sekeljic ◽  
Mihailo Bezmarevic ◽  
Alastair Forbes

Introduction. Self-poisoning is not frequent during pregnancy. We present a successful treatment of a woman 20 weeks pregnant with twins with self-inflicted poisoning by a caustic substance. Case outline. A 34-year-old pregnant woman was admitted to our institution after self-inflicted poisoning with concentrated acetic acid. Initial clinical evaluation showed severe diffuse erythema of the mouth and oropharynx, a systemic inflammatory response syndrome, and dichorionic diamniotic twin pregnancy in the 20th week of gestation confirmed on abdominal ultrasound. An indirect laryngoscopic examination revealed severe generalized hyperemia of the laryngeal mucosa with corrosive changes in the pharyngeal mucosa, especially of the posterior pharyngeal wall. Due to pain, urgent esophagogastroduodenoscopy could not be performed, and because of the patient?s refusal a feeding gastrostomy or jejunostomy could not be created. The patient was given ?all-in-one? total parenteral nutrition in addition to other supportive therapy. Gradual introduction of enteral nutrition via a nasoenteric tube placed in the second month of hospitalization failed due to severe vomiting. After almost three months of total parenteral nutrition, enteral nutrition was nevertheless introduced; we then started with oral fluids, increasing gradually to a regular diet, and needed almost half a month to reach the adequate nutritional goal. The delivery was spontaneous at the 36th week of pregnancy and the patient gave birth to two normal healthy girls (46 cm / 2,580 g and 48 cm / 2,960 g, respectively). Conclusion. Total parenteral nutrition can be a safe choice for providing prolonged and adequate nutritional intake even in a twin pregnancy without adverse effects on fetal growth.


1990 ◽  
Vol 14 (5) ◽  
pp. 501-507 ◽  
Author(s):  
Elie Hamaoui ◽  
Rose Lefkowitz ◽  
Lynda Olender ◽  
Elissa Krasnopolsky-Levine ◽  
Maria Favale ◽  
...  

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