scholarly journals Measurements of hemodynamics in coronary artery bypass using particle image velocimetry : an in-vitro study

2007 ◽  
Author(s):  
Wenfa Ji
Author(s):  
Ryan A. Peck ◽  
Edver Bahena ◽  
Reza Jahan ◽  
Guillermo Aguilar ◽  
Hideaki Tsutsui ◽  
...  

2021 ◽  
Vol 17 (10) ◽  
pp. 1951-1959
Author(s):  
Qiyong Wu ◽  
Xiaoqiang Tang ◽  
Haifeng Shi ◽  
Yong Zhang ◽  
Tao Wang ◽  
...  

Magnetic resonance imaging is widely used to identify and monitor thrombi in grafted vessels following coronary artery bypass grafting surgery (CABG). We produced a biosensor, P1Cm-SPIO-Cy5.5, composed of P1Cm peptide, superparamagnetic iron oxide nanoparticles (SPIO), and polyethylene glycol (PEG), for use in MRI thrombus imaging. Activated platelets induced by adenosine diphosphate were used for combination tests in vitro. A rat model of common carotid artery thrombosis was used for anti-thrombus experiments in vivo. P1Cm-SPIO-Cy5.5 remains stable in vitro and has good anticoagulation capacity. It can bind specifically to activated platelets and thrombi. In rats that underwent bypass surgery, P1Cm-SPIO-Cy5.5 could detect and label thrombi over a long period, and prevent thrombosis in grafted vessels. P1Cm-SPIO-Cy5.5 improved cardiac function in rats following CABG surgery. P1Cm-SPIO-Cy5.5 is a potential sensor for use in MRI for the early diagnosis and prevention of thrombosis after CABG surgery.


2013 ◽  
Vol 135 (3) ◽  
Author(s):  
Alinaghi Salari ◽  
M. B. Shafii ◽  
Shapour Shirani

Microbubbles are broadly used as ultrasound contrast agents. In this paper we use a low-cost flow focusing microchannel fabrication method for preparing microbubble contrast agents by using some surface active agents and a viscosity enhancing material to obtain appropriate microbubbles with desired lifetime and stability for any in vitro infusion for velocity measurement. All the five parameters that govern the bubble size extract and some efforts are done to achieve the smallest bubbles by adding suitable surfactant concentrations. By using these microbubbles for the echo-particle image velocimetry method, we experimentally determine the velocity field of steady state and pulsatile pipe flows.


2011 ◽  
Vol 37 (3) ◽  
pp. 450-464 ◽  
Author(s):  
Fuxing Zhang ◽  
Craig Lanning ◽  
Luciano Mazzaro ◽  
Alex J. Barker ◽  
Phillip E. Gates ◽  
...  

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