scholarly journals STRUCTURAL CLASSIFICATION OF PROTEINS USING IMAGE BASED MACHINE LEARNING

2021 ◽  
Author(s):  
Daniel Franklin

Classification of proteins is an important area of research that enables better grouping of proteins either by their function, evolutionary similarities or in their structural makeup. Structural classification is the area of research that this thesis focuses on. We use visualizations of proteins to build a machine learning class prediction model, that successfully classifies proteins using the Structural Classification of Proteins (SCOP) framework. SCOP is a well-researched classification with many approaches using a representation of a proteins secondary structure in a linear chain of structures. This thesis uses a novel approach of rendering a three dimensional visualization of the protein itself and then applying image based machine learning to determine a protein’s SCOP classification. The resulting convolutional neural network (CNN) method has achieved average accuracies in the range 78-87% on the 25PDB dataset, which is better than or equal to the existing methods.

2021 ◽  
Author(s):  
Daniel Franklin

Classification of proteins is an important area of research that enables better grouping of proteins either by their function, evolutionary similarities or in their structural makeup. Structural classification is the area of research that this thesis focuses on. We use visualizations of proteins to build a machine learning class prediction model, that successfully classifies proteins using the Structural Classification of Proteins (SCOP) framework. SCOP is a well-researched classification with many approaches using a representation of a proteins secondary structure in a linear chain of structures. This thesis uses a novel approach of rendering a three dimensional visualization of the protein itself and then applying image based machine learning to determine a protein’s SCOP classification. The resulting convolutional neural network (CNN) method has achieved average accuracies in the range 78-87% on the 25PDB dataset, which is better than or equal to the existing methods.


Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2503
Author(s):  
Taro Suzuki ◽  
Yoshiharu Amano

This paper proposes a method for detecting non-line-of-sight (NLOS) multipath, which causes large positioning errors in a global navigation satellite system (GNSS). We use GNSS signal correlation output, which is the most primitive GNSS signal processing output, to detect NLOS multipath based on machine learning. The shape of the multi-correlator outputs is distorted due to the NLOS multipath. The features of the shape of the multi-correlator are used to discriminate the NLOS multipath. We implement two supervised learning methods, a support vector machine (SVM) and a neural network (NN), and compare their performance. In addition, we also propose an automated method of collecting training data for LOS and NLOS signals of machine learning. The evaluation of the proposed NLOS detection method in an urban environment confirmed that NN was better than SVM, and 97.7% of NLOS signals were correctly discriminated.


1999 ◽  
Vol 27 (1) ◽  
pp. 254-256 ◽  
Author(s):  
T. J. P. Hubbard ◽  
B. Ailey ◽  
S. E. Brenner ◽  
A. G. Murzin ◽  
C. Chothia

Author(s):  
YUESHENG HE ◽  
YUAN YAN TANG

Graphical avatars have gained popularity in many application domains such as three-dimensional (3D) animation movies and animated simulations for product design. However, the methods to edit avatars' behaviors in the 3D graphical environment remained to be a challenging research topic. Since the hand-crafted methods are time-consuming and inefficient, the automatic actions of the avatars are required. To achieve the autonomous behaviors of the avatars, artificial intelligence should be used in this research area. In this paper, we present a novel approach to construct a system of automatic avatars in the 3D graphical environments based on the machine learning techniques. Specific framework is created for controlling the behaviors of avatars, such as classifying the difference among the environments and using hierarchical structure to describe these actions. Because of the requirement of simulating the interactions between avatars and environments after the classification of the environment, Reinforcement Learning is used to compute the policy to control the avatar intelligently in the 3D environment for the solution of the problem of different situations. Thus, our approach has solved problems such as where the levels of the missions will be defined and how the learning algorithm will be used to control the avatars. In this paper, our method to achieve these goals will be presented. The main contributions of this paper are presenting a hierarchical structure to control avatars automatically, developing a method for avatars to recognize environment and presenting an approach for making the policy of avatars' actions intelligently.


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