scholarly journals Missed Diagnosis of Phyllodes Tumour And Its Implications - A Case Report

2021 ◽  
Vol 29 (2) ◽  
pp. 182-184
Author(s):  
Prosunto Kumar Das ◽  
AZM Mahfuzur Rahman ◽  
Md Nayeem Dewan Sina ◽  
Abu Masud Al Mamun

Phyllodes tumours are rare fibroepithelial tumours that accounts for less than 1% of all breast tumours. Phyllodes tumours tend to grow quickly but they rarely spread outside the breast. Although most phyllodes tumours are benign, some are malignant and some are borderline. It is often underdiagnosed by pathologists and under treated by surgeon. Its heterogenicity makes phyllodes tumour a challenge for the clinicians and the pathologists. Accurate preoperative diagnosis by Fine Needle Aspiration Cytology or by Core biopsy or peroprative diagnosis by Frozen section biopsy is essential for adequate surgical treatment. This case describes a missed diagnosis of phyllodes tumour both by cytopathologically and histopathologically. J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 182-184

2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118


2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.


2019 ◽  
Vol 133 (03) ◽  
pp. 227-229 ◽  
Author(s):  
M Suzuki ◽  
Y Nakaegawa ◽  
T Kobayashi ◽  
T Kawase ◽  
T Matsuzuka ◽  
...  

AbstractObjectivesThis study focused on parotid gland tumours diagnosed as benign by fine-needle aspiration cytology and investigated the necessity of frozen section biopsy.MethodsThere were 104 cases of parotid gland tumour where fine-needle aspiration cytology was benign and frozen section biopsy was subsequently performed, between April 2006 and June 2016. In this retrospective study, the results of frozen section biopsy were analysed and compared with the final histological diagnosis.ResultsAmong the 104 cases diagnosed as benign by fine-needle aspiration cytology, 102 cases and 2 cases were diagnosed as benign and malignant, respectively, by frozen section biopsy. The final histological diagnoses showed that 98 cases were benign and 6 cases were malignant. The sensitivity and specificity values of frozen section biopsy in detecting malignant tumours were 33 per cent and 100 per cent, respectively.ConclusionThe necessity of frozen section biopsy in cases with benign fine-needle aspiration cytology may be low in parotid gland surgery.


2015 ◽  
Vol 5 (2) ◽  
pp. 342-344
Author(s):  
Ayesha Siddiqua ◽  
Nargis Akhtar ◽  
Lubna Khondaker ◽  
Md Aminul Islam ◽  
Md Mahabubur Rahaman ◽  
...  

Objective : The objective of this study was to evaluate the accuracy of Fine Needle Aspiration Cytology (FNAC) in diagnosis of Papulonodular skin disease.Methodology : This prospective study was carried out in Bangabandhu Sheik Mujib Medical University (BSMMU) in the department of Dermatology and Veneral disease and department of Pathology. Study period was March 2012 to August 2012 (six months). Thirty (30) patients with papulonodular skin lesion for more than 6 weeks were enrolled. Data were collected and analysis was done by using SPSS.Results : Among 30 patients, 14 cases which were histopathologically diagnosed as epidermal inclusion cyst, pilar cyst, lipoma were also diagnosed positive by FNAC and accuracy were 100%. Rest 16 cases which were histopathologically positive as lupus vulgaris, prurigo nodularies,post –kala-a –zar dermal leishmaniasis, erythema nodosum, mycosis fungoides were diagnosed negative by FNAC . Overall accuracy of FNAC was only 46.7%.Conclusions : FNAC has significant limitation for diagnosis of papulonodular skin disease and not a good alternative to histopathology in diagnosis of papulonodular skin disease.Northern International Medical College Journal Vol.5(2) 2014: 342-344


1993 ◽  
Vol 47 (6-7) ◽  
pp. 254
Author(s):  
C. De Gaudio ◽  
A. Carpi ◽  
A. Mita ◽  
A. De Biase Lluciani ◽  
M.G. Toni

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