scholarly journals Mixed Connective Tissue Disease- A Rare and Distinct Rheumatological Case Study

KYAMC Journal ◽  
2017 ◽  
Vol 8 (1) ◽  
pp. 61-63
Author(s):  
Kazi Shihab Uddin ◽  
Muhammad Alamgir Mandal ◽  
Md Zulfikar Ali
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Detailed History ◽  
History Of ◽  
Skin Conditions ◽  
Bluish Discoloration

In this article we present this 35 year old lady with history of fever, multiple joints pain with swelling and skin conditions such as tightening, glistening and bluish discoloration while exposure to cold. After taking detailed history and clinical examinations, she was found to have features consistent with multiple rheumatological conditions such as systemic lupus erythematosus and systemic sclerosis. With directed and specific investigation she was diagnosed to have Mixed Connective Tissue disorder.KYAMC Journal Vol. 8, No.-1, Jul 2017, Page 61-63

Bone, joint and connective tissue disorders

2021 ◽  
pp. 245-252
Author(s):  
David Howell
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Ankylosing Spondylitis ◽  
Connective Tissue ◽  
Musculoskeletal Disorders ◽  
Lupus Erythematosus ◽  
Anaesthetic Management ◽  
Systemic Lupus ◽  
Anaesthetic Practice

This chapter describes the anaesthetic management of the patient with those musculoskeletal disorders which are relevant to anaesthetic practice. Topics covered include rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus (SLE); systemic sclerosis; scoliosis and achondroplasia. For each topic, pre-operative investigation and optimisation, treatment, and anaesthetic management are described.

Bone, joint, and connective tissue disorders

2018 ◽  
Author(s):  
Colin Berry
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Ankylosing Spondylitis ◽  
Connective Tissue ◽  
Musculoskeletal Disorders ◽  
Lupus Erythematosus ◽  
Anaesthetic Management ◽  
Connective Tissue Disorders ◽  
Systemic Lupus

This chapter describes the anaesthetic management of the patient with those musculoskeletal disorders which are relevant to anaesthetic practice. Topics covered include rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, systemic sclerosis, scoliosis, and achondroplasia. For each topic, preoperative investigation and optimization, treatment, and anaesthetic management are described.

scholarly journals The Microbiome in Connective Tissue Diseases and Vasculitides: An Updated Narrative Review

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Rossella Talotta ◽  
Fabiola Atzeni ◽  
Maria Chiara Ditto ◽  
Maria Chiara Gerardi ◽  
Piercarlo Sarzi-Puttini
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Lupus Erythematosus ◽  
Connective Tissue Diseases ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Narrative Review ◽  
Systemic Lupus ◽  
Sjögren‘S Syndrome

Objective. To provide a narrative review of the most recent data concerning the involvement of the microbiome in the pathogenesis of connective tissue diseases (CTDs) and vasculitides.Methods. The PubMed database was searched for articles using combinations of words or terms that included systemic lupus erythematosus, systemic sclerosis, autoimmune myositis, Sjögren’s syndrome, undifferentiated and mixed CTD, vasculitis, microbiota, microbiome, and dysbiosis. Papers from the reference lists of the articles and book chapters were reviewed, and relevant publications were identified. Abstracts and articles written in languages other than English were excluded.Results.We found some evidence that dysbiosis participates in the pathogenesis of systemic lupus erythematosus, systemic sclerosis, Sjögren’s syndrome, and Behçet’s disease, but there are still few data concerning the role of dysbiosis in other CTDs or vasculitides.Conclusions.Numerous studies suggest that alterations in human microbiota may be involved in the pathogenesis of inflammatory arthritides as a result of the aberrant activation of the innate and adaptive immune responses. Only a few studies have explored the involvement of dysbiosis in other CTDs or vasculitides, and further research is needed.

scholarly journals Digital dry gangrene as a primary manifestation of systemic lupus erythematosus

2019 ◽  
Vol 12 (12) ◽  
pp. e230869
Author(s):  
Satyendra Kumar Sonkar ◽  
Satish Kumar ◽  
Virendra Atam ◽  
Shyam Chand Chaudhary
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Lupus Erythematosus ◽  
Signs And Symptoms ◽  
Systemic Lupus ◽  
Initial Manifestation ◽  
Course Of Disease ◽  
Rare Phenomenon

Digital dry gangrene is commonly seen in cases of connective tissue disease such as systemic sclerosis. In systemic lupus erythematosus (SLE) digital gangrene is rare. As initial manifestation, it is again a rare phenomenon because it occurs late in the course of disease. Here we are reporting the case of a woman who was having extensive cutaneous gangrene of her fingers and toes, as a first and foremost presentation without any other typical signs and symptoms of SLE. Her serology was positive for SLE. The patient was treated conservatively and responded well.

scholarly journals Dystrophic calcifications in case of a patient with systemic lupus erythematosus – case report and literature review

2021 ◽  
Author(s):  
Anna Kruszewska ◽  
Agnieszka Owczarczyk-Saczonek ◽  
Waldemar Placek ◽  
Magdalena Krajewska-Włodarczyk
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Treatment Algorithm ◽  
Systemic Lupus ◽  
Normal Range ◽  
Different Types ◽  
History Of ◽  
Subcutaneous Tissues ◽  
Nodular Lesions

Introduction: Cutis calcification is the deposition of calcium in the skin and subcutaneous tissues and is classified into four subsets. Dystrophic calcifications are the most common type of skin calcification, occurring mainly in damaged tissues or in course of autoimmune disease. However, the coexistance of systemic lupus erythematosus (SLE) and soft tissue calcification is described rarely. Aim: This article presents a case of dystrophic calcifications in the buttocks area in a 49-year-old woman with a 17-year history of SLE. Case study: We report a case of 49-year-old women with SLE who developed nodular lesions in the buttock area. The radiological and histopatological examinations of the nodules showed presence of calcifications. The calcium metabolism parameters were in a normal range. The diagnosis of dystrophic calcinosis in the course of SLE was established. Results and discussion: Dystrophic calcifications associated with autoimmune diseases are common, but occur rarely in SLE. It should be noted that patients with SLE can also develop calcifications of different types like metastatic or iatrogenic. Dystrophic calcifications in SLE usually present as small nodules on buttocks or limbs. The pathophysiology remains unclear, however, there are some theories that inflammation and vascular ischemia play a role in its process. Conclusions: Calcifications in case of patients with SLE rarely require treatment. Several pharmacologic and surgical therapies have been tested with variable results. Additional research to establish an accepted treatment algorithm should be conducted.

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