Spherical Aberration, Contrast Sensitivity and Depth of Focus With Three Aspherical Intraocular Lenses

Purpose. To compare the effect of spherical aberration on optical quality in eyes with two different aspherical intraocular lenses. Methods. 120 eyes of 60 patients underwent phacoemulsification. In patients’ eyes, an aberration-free IOL (Aspira-aA; Human Optics) or an aberration-correcting aspherical IOL (Tecnis ZCB00; Abott Medical Optics) was randomly implanted. After surgery, contrast sensitivity and wavefront measurements as well as tilt and decentration measurements were performed. Results. Contrast sensitivity was significantly higher in eyes with Aspira lens under mesopic conditions with 12 cycles per degree (CPD) and under photopic conditions with 18 CPD (p=0.02). Wavefront measurements showed a higher total spherical aberration with a minimal pupil size of 4 mm in the Aspira group (0.05 ± 0.03) than in the Tecnis group (0.03 ± 0.02) (p=0.001). Strehl ratio was higher in eyes with Tecnis (0.28 ± 0.17) with a minimal pupil size larger than 5 mm than that with Aspira (0.16 ± 0.14) (p=0.04). In pupils with a minimum diameter of 4 mm spherical aberration had a significant effect on Strehl ratio, but not in pupils with a diameter less than 4 mm. Conclusions. Optical quality was better in eyes with the aberration-correcting Tecnis IOL when pupils were large. In contrast, this could not be shown in eyes with pupils under 4 mm or larger. This trial is registered with Clinicaltrials.gov NCT03224728.

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Extended Depth of Focus With Induced Spherical Aberration in Light-Adjustable Intraocular Lenses

American Journal of Ophthalmology ◽

10.1016/j.ajo.2013.08.009 ◽

2014 ◽

Vol 157 (1) ◽

pp. 142-149 ◽

Cited By ~ 21

Author(s):

Eloy A. Villegas ◽

Encarna Alcón ◽

Sandra Mirabet ◽

Inés Yago ◽

José María Marín ◽

...

Keyword(s):

Spherical Aberration ◽

Intraocular Lenses ◽

Depth Of Focus ◽

Extended Depth Of Focus

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Influence of Angle Alpha on Visual Quality after Implantation of Extended Depth of Focus Intraocular Lenses

10.21203/rs.3.rs-257390/v1 ◽

2021 ◽

Author(s):

Miaomiao Qin ◽

Min Ji ◽

Tianqiu Zhou ◽

Yurong Yuan ◽

Jiawei Luo ◽

...

Keyword(s):

Visual Acuity ◽

Spherical Aberration ◽

Visual Quality ◽

Intraocular Lenses ◽

Patient Questionnaire ◽

Modulation Transfer ◽

Depth Of Focus ◽

Extended Depth Of Focus ◽

Postoperative Changes ◽

Angle Alpha

Abstract Background: To assess postoperative changes in angle alpha, and to evaluate the postoperative visual quality of patients with different angle alpha values after implantation of extended depth of focus (EDOF) intraocular lenses (IOLs).Methods: Seventy-nine eyes of 79 patients who had phacoemulsification with EDOF IOLs implantation were enrolled. A cut-off value of 0.3 mm, 0.4 mm, and 0.5 mm in preoperative angle alpha was chosen to divide eyes into groups. Distance, intermediate, and near visual acuities, modulation transfer function (MTF), and aberrations were recorded during a 6-month follow-up. A patient questionnaire was completed. Results: There were no significant differences in angle alpha postoperatively compared to preoperatively. No significant differences were found in visual acuity and MTF between all groups. With 5mm pupil diameter, there were significant differences of higher-order aberrations and spherical aberration in ocular aberration and internal aberration between angle alpha＜0.4 mm and angle alpha≥ 0.4 mm. Additionally, significant differences of coma were also added in cut-off value of 0.5 mm. When the value of angle alpha is 0.4 mm or higher, there were significant differences in the score of halos and glare.Conclusions: Angle alpha did not affect visual acuity, but the value of 0.4 mm or higher in angle alpha affected the visual quality under scotopic conditions and occurrence of halos and glare. For patients with 0.4 mm or higher in angle alpha, the decision to implant a EDOF IOL should be carefully considered.

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Visual Function and Subjective Quality of Life in Chinese Cataract Patients after Implantation with Aspheric Intraocular Lenses

European Journal of Ophthalmology ◽

10.5301/ejo.2011.6441 ◽

2011 ◽

Vol 21 (6) ◽

pp. 732-740

Author(s):

Yanwen Fang ◽

Yi Lu ◽

Xinhua Wu ◽

Aizhu Miao ◽

Yi Luo

Keyword(s):

Visual Acuity ◽

Contrast Sensitivity ◽

Visual Function ◽

Spherical Aberration ◽

Visual Quality ◽

Intraocular Lenses ◽

Subjective Quality Of Life ◽

Significant Difference ◽

The Mean ◽

Cataract Patients

Purpose. To evaluate and compare the objective and subjective visual function after implantation of 2 aspheric intraocular lenses (IOLs) in Chinese cataract patients. Methods. Forty-one eyes of 28 patients with cataract were randomly assigned to receive either the MC X11 ASP IOL or the AcrySof IQ IOL. Three months postoperatively, best-corrected visual acuity (BCVA), contrast sensitivity, wavefront aberrations, and subjective visual quality were measured. The degree of posterior capsule opacification (PCO) was recorded at last follow-up. Results. Postoperative mean monocular BCVA was 0.05±0.13 logMAR in the MC X11 group and 0.05±0.08 logMAR in the IQ group. There was no significant difference in visual acuity, contrast sensitivity, subjective visual quality, and degree of PCO between the 2 groups. For a 6-mm pupil diameter, the mean spherical aberration (Z40) was 0.075±0.076 μm in the MC X11 group and 0.056±0.111 μm in the IQ group. However, 45.5% and 57.9% of the eyes in the MC X11 and IQ groups had values >0.10 μm, respectively. The mean RMS values of the high-order aberrations were similar between the 2 groups except the higher fifth- and sixth-order aberrations, which were significantly higher in the MC X11 group. Conclusions. Both IOLs provided similar and good visual outcomes. However, the data suggest that the amount of negative spherical aberration generated by current available aspheric IOLs might not be optimal for Chinese eyes.

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Spherical Aberration and Depth of Focus in Eyes Implanted with Aspheric and Spherical Intraocular Lenses

Ophthalmology ◽

10.1016/j.ophtha.2007.01.024 ◽

2007 ◽

Vol 114 (11) ◽

pp. 2050-2054 ◽

Cited By ~ 84

Author(s):

Karolinne Maia Rocha ◽

Eduardo S. Soriano ◽

Wallace Chamon ◽

Maria Regina Chalita ◽

Walton Nosé

Keyword(s):

Spherical Aberration ◽

Intraocular Lenses ◽

Depth Of Focus

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Functional visual acuity after implantation of diffractive extended depth-of-focus intraocular lenses using an echelett optics

BMC Ophthalmology ◽

10.1186/s12886-021-02189-7 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Toshihiro Sakisaka ◽

Keiichiro Minami ◽

Keita Takada ◽

Yosai Mori ◽

Kazunori Miyata

Keyword(s):

Visual Acuity ◽

Contrast Sensitivity ◽

Visual Function ◽

Case Series ◽

Intraocular Lenses ◽

Depth Of Focus ◽

Mean Response Time ◽

Extended Depth Of Focus ◽

Functional Visual Acuity ◽

The Mean

Abstract Background The prospective comparative case series aimed to evaluate all-distance visual acuity, contrast sensitivity, and functional visual acuity (FVA) of eyes with diffractive extended depth-of-focus (EDOF) intraocular lenses (IOLs) using an echelett optics and monofocal IOLs with the same platform. Methods Diffractive EDOF and monofocal IOLs were implanted in 27 eyes of 27 patients each. At 3 months after implantation, all-distance visual acuities at distances of 0.3, 0.5, 0.7, 1, 2, 3, and 5 m were measured under distance-corrected. Static visual function was also examined using photopic contrast sensitivity and area under the logarithmic contrast sensitivity function (AULCSF). Dynamic visual function was examined with FVA, and mean FVA value, visual maintenance ratio (VMR), mean response time, and number of blinks were evaluated. These outcomes were compared between the two IOLs. Results The mean distance-corrected visual acuities were better at distances of 0.7 m or nearer in eyes with EDOF IOLs. There was no difference in the contrast sensitivities (P > 0.22). In the FVA results, no difference was found in mean FVA and VMR (P > 0.68). Conclusion The static and dynamic evaluations of postoperative visual functions demonstrated that the visual function of eyes with EDOF IOLs under photopic and distance-corrected conditions was comparable to eyes with monofocal IOLs.

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Efficacy and safety of extended depth of focus intraocular lenses in cataract surgery: a systematic review and meta-analysis

10.21203/rs.2.11472/v2 ◽

2019 ◽

Author(s):

Jing Liu ◽

Yi Dong ◽

Yan Wang

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Intraocular Lenses ◽

Control Group ◽

Efficacy And Safety ◽

Depth Of Focus ◽

Extended Depth Of Focus ◽

Significant Difference ◽

Near Visual Acuity

Abstract Background : This study aims to evaluate the efficacy and safety of extended depth of focus (EDOF) intraocular lenes (IOLs) in cataract surgery. Methods: All comparative clinical trials that involved bilaterally implanting EDOF IOLs in patients with cataract were retrieved from the literature database. We used random effects models to pool weighted mean differences (WMD) and risk ratio (RR) for continuous and dichotomous variables, respectively. Results: Nine studies with a total of 1336 eyes were identified. The subgroup analysis was conducted according to the type of IOLs used in the control group. Compared with monofocal IOLs, EDOF IOLs produced better uncorrected intermediate visual acuity (WMD: -0.17, 95% CI: -0.26 to -0.08, P = 0.0001) and uncorrected near visual acuity (WMD: -0.17, 95% CI: -0.21 to -0.12, P < 0.00001). EDOF IOLs resulted in reduced contrast sensitivity, more frequent halos, however, higher spectacle independence (RR: 2.81, 95% CI: 1.06 to 7.46, P = 0.04) than monofocal IOLs. Compared with trifocal IOLs, EDOF IOLs produced worse near visual acuity (MD: 0.10, 95% CI: 0.07 to 0.13, P<0.0001). EDOF IOLs performed better than trifocal IOls in contrast sensitivity, and there were no significant difference in halos and spectacle independence. Serious postoperative complications were rare, with no adverse events were reported in most studies. Conclusions: Increasing the risk of contrast reduction and more frequent halos, EDOF IOLs provided better intermediate and near VAs than monofocal IOLs. At the expense of near vision, patients receiving EDOF IOLs have better contrast sensitivity than those receiving trifocal IOLs. Halo incidence and spectacle independence of EDOF IOLs were similar to those of trifocal IOLs.

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In Vitro Optical Performance of Multifocal and Extended Depth-of-Focus Intraocular Lenses in Spherical Aberration Conditions

Journal of Cataract & Refractive Surgery ◽

10.1097/j.jcrs.0000000000000869 ◽

2021 ◽

Vol Publish Ahead of Print ◽

Author(s):

Soohyun Park ◽

Myoung Joon Kim ◽

Ki Hean Kim

Keyword(s):

Spherical Aberration ◽

Intraocular Lenses ◽

Optical Performance ◽

Depth Of Focus ◽

Extended Depth Of Focus

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Comparative Analysis of Visual Performance and Astigmatism Tolerance with Monofocal, Bifocal, and Extended Depth-of-Focus Intraocular Lenses Targeting Slight Myopia

Journal of Ophthalmology ◽

10.1155/2020/9283021 ◽

2020 ◽

Vol 2020 ◽

pp. 1-11

Author(s):

Jie Xu ◽

Tianyu Zheng ◽

Yi Lu

Keyword(s):

Contrast Sensitivity ◽

Significant Negative Correlation ◽

Optical Quality ◽

Corneal Astigmatism ◽

Intraocular Lenses ◽

Visual Performance ◽

Depth Of Focus ◽

Visual Outcomes ◽

Extended Depth Of Focus ◽

Visual Function Questionnaire

Purpose. To compare the visual performance and astigmatism tolerance of 3 intraocular lens (IOL) groups: monofocal, bifocal, and extended depth-of-focus (EDOF) IOLs targeting slight myopia. Methods. Overall, there were 60 cataract surgery eyes from 60 patients with implantation of a monofocal, bifocal, or EDOF IOL (20 eyes in each IOL group). The EDOF IOLs targeted slight myopia (−0.25 D to −0.75 D). Intragroup comparison of visual acuity, defocus curve, objective optical quality, contrast sensitivity, visual function questionnaire scores, patients’ overall satisfaction, and the astigmatism tolerance was performed 3 months after surgery. Results. The EDOF group provided equivalently excellent distance visual outcomes (0.06 ± 0.12) as the monofocal (0.06 ± 0.09) and bifocal (0.03 ± 0.09) groups P = 0.554 , better intermediate vision than the other 2 groups P < 0.05 , and similarly satisfactory near visual outcomes (0.23 ± 0.16 at 20 cm, and 0.17 ± 0.14 at 33 cm) as the bifocal group (0.28 ± 0.14 at 20 cm and 0.08 ± 0.10 at 33 cm) P > 0.05 . The contrast sensitivity of EDOF IOL was slightly decreased compared to that of monofocal IOL, but it was better than that of bifocal IOL. The EDOF group showed significantly higher satisfaction than the bifocal group did when preoperative corneal astigmatism was 0.75 D or greater P = 0.009 . A significant negative correlation between the corneal astigmatism and patient satisfaction was observed in only the bifocal group. Conclusions. The EDOF IOLs targeting slight myopia offered satisfactory visual outcomes at an extended range from far to near distances. The EDOF and monofocal IOLs showed a better tolerance to astigmatism than did the bifocal IOL.

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