Cochlear Implantation in Advanced Otosclerosis: Pitfalls and Successes

Purpose of Review This review will highlight recent outcome-based evidence guiding decision making for cochlear implantation in advanced otosclerosis, related complications, and technical surgical considerations in otosclerosis and the obstructed cochlea. Recent Findings Cochlear implantation in advanced otosclerosis results in consistent, excellent auditory outcomes with improvement in both objective speech recognition scores and subjective quality of life measures. Facial nerve stimulation may occur at higher rates in otosclerosis cochlear implant recipients. Cochlear implantation in the setting of luminal obstruction in osteosclerotic patients may be managed with altered surgical technique to achieve successful auditory improvements. Pre-operative imaging with high resolution CT or MRI may help anticipate intraoperative challenges and post-operative complications in cochlear implantation. Summary Cochlear implantation is an established, successful treatment for profound hearing loss in advanced otosclerosis. Surgeon knowledge of outcomes, complications, and potential surgical challenges is important to appropriately counsel patients regarding auditory rehabilitation options in advanced otosclerosis.

Impact of the COVID-19 Pandemic on Mental Well-Being. A Nationwide Online Survey Covering Three Pandemic Waves in Poland

The COVID-19 pandemic has a significant impact on human life. This study aims to assess the prevalence of depressive and anxiety symptoms, and the assessment of the quality of life in different stages of the COVID-19 pandemic based on an online nationwide survey. The study was based on a voluntary, anonymous, and authors' own questionnaire. The first section assesses sociodemographic status. Then, standardized psychometric tools were used such as the Beck Depression Inventory (BDI), the Generalized Anxiety Disorder Assessment (GAD-7), and the Manchester Short Assessment of Quality of Life (MANSA). The study was conducted in three stages corresponding to the waves of the COVID-19 pandemic in Poland. The survey involved 5,790 respondents; 2,457, 1,626, and 1,707 for the first, second, and third pandemic wave, respectively. It was found that anxiety and depressive symptoms increased as the pandemic progressed. There was no significant effect on the subjective quality-of-life assessment. Moreover, there was a gradual decrease in anxiety about being infected with COVID-19 as well as reduced adherence to the Minister of Health's recommendations. As the COVID-19 pandemic progressed, depressive and anxiety symptoms increased among Poles. Women, singles, and people with prior psychiatric treatment are more likely to develop the aforementioned symptoms.

Comparison of mental health and subjective quality of life in sexual minority versus heterosexual autistic adults

Background: Although disparities in mental health and subjective quality of life have been reported for autistic adults, reasons for these disparities are poorly understood. A potential factor in these disparities is exposure to social stressors related to minority status (i.e., minority stress), including stigma and discrimination. Autistic individuals are more likely than non-autistic individuals to possess other minority identities, including sexual minority identities. However, to date, few studies have examined whether sexual minority autistic adults experience diminished mental health relative to heterosexual autistic adults, and no research has examined subjective quality of life for sexual minority compared to heterosexual autistic adults.Methods: Participants were 679 autistic adults aged 18.5 to 83.3 years recruited through Simons Powering Autism Research Knowledge Research Match. Participants completed surveys online, including measures of anxious and depressive symptomatology, perceived stress, and subjective quality of life. Participants reported their sexual orientation and other socio-demographic variables. Results: A large proportion of autistic adults reported a sexual minority identity (43.4%). Sexual minority autistic adults showed poorer mental health and lower subjective quality of life relative to heterosexual autistic adults. Diminished quality of life in the sexual minority group appears to be driven by the strength of the effects for gay and pansexual compared to heterosexual autistic adults. Conclusion: Understanding factors that may be related to poorer mental health and decreased subjective quality of life in autistic adults is critical and has been identified as a research priority among autistic stakeholders. The findings reported here underscore the need to examine mental health and subjective quality of life disparities among autistic individuals within a societal context, taking into consideration the potential of intersecting minority identities and increased social stressors, as these hold the potential to increase risks for poorer outcome.

A mixed methods exploration of the role of multi-family groups in community treatment of patients with depression and anxiety in Pakistan

Background An open, non-controlled trial was conducted to explore the feasibility, experiences and outcomes of multi-family groups in community mental health care of patients with depression and anxiety. Methods The study was conducted in community settings within the catchment area of a free of cost primary care center in Karachi, Pakistan. 30 patients with symptoms of depression and anxiety, their caregivers and 3 lay counsellors were recruited enrolled in the study between May–September 2019. Patients were enrolled for monthly multi-family group meetings conducted over 6 months in groups of 5–6 patients and 1–2 nominated caregivers each. Meetings were facilitated by the non-specialist trained counsellors. The primary outcome was quality of life (assessed using Manchester Short Assessment of Quality of Life) and secondary outcomes were symptoms of depression and anxiety (assessed on Aga Khan University Depression and Anxiety Scale), social outcomes (Social Outcome Index), and caregiver burden (Burden Assessment Scale). Change in all measures was assessed pre and 6-month post intervention using t-test. In-depth interviews were conducted with 7 patients, 7 caregivers and the 3 lay counsellors. Results A total of 36 family intervention meetings were conducted with six groups with a total of 30 patients, 34 caregivers and 3 counsellors. Between baseline and the end of the intervention, subjective quality of life increased significantly from 3.34 to 4.58 (p < 0.001, 95% CI 0.93–1.54). Self-reported depression and anxiety scores reduced from 34.7 to 19.5 (p < 0.001, 95% CI 10.8–19.8) and the Social Outcome Index improved from 3.63 to 4.52 (p < 0.001, 95% CI 0.39–1.39). There was no change in family burden. Participants reported that the group meetings were seen as a safe space for shared learning, and that the experience helped improve self-regulation of emotions and behaviors and instilled a sense of belonging. Conclusion Multi-family groups in community treatment of common mental health disorders facilitated by non-specialist mental health service providers is feasible, experienced positively and has the potential for large and positive effects on subjective quality of life, self-reported depression and anxiety, and objective social outcomes. Trial Registration: ISRCTN, ISRCTN12299326. Registered 05 June 2019. Retrospectively registered, https://doi.org/10.1186/ISRCTN12299326.

The Impact of Retirement on Happiness and Loneliness in Poland—Evidence from Panel Data

This paper examines the impact of retirement on people’s subjective quality of life, as expressed by their levels of happiness and loneliness, in Poland. We analysed five waves of the Social Diagnosis panel survey conducted between 2007 and 2015. To account for unobserved individual heterogeneity, we employed fixed effects ordered logit models and fixed effect logistic models for the panel data. We found that the respondents’ happiness levels did not change after they retired, and that the introduction of interactions between retirement and employment did not alter these findings. However, the results of the loneliness model showed that the probability of being lonely increased among males after retirement. Second, the outcomes of interactions between retirement and employment suggested that not working after retirement increased the likelihood of being lonely among men, whereas engaging in bridge employment decreased the chances of being lonely among men. These findings may indicate that combining retirement with employment may be a source of social interaction, which can provide protection against loneliness, and which may, in turn, be positively related to other factors (i.e., subjective quality of life, health status, and mortality).

Explore Associations between Subjective Well-Being and Eco-Logical Footprints with Fixed Effects Panel Regressions

As environmental degradations constantly and directly threaten human well-being, it is imperative to explore the environmental impacts on people’s happy life. This research investigates the association between subjective well-being (SWB) and ecological footprints (EF) through space-time fixed effects panel regressions. EF, as a vital indicator of environmentally sustainable development, plays a vital role in ecological balance. SWB determines the subjective quality of life for humanity. EF-related factors and socio-economic indexes referring to GDP, urbanization rate, income, education, health, political stability, and political voice accountability in 101 countries were captured. Compared with ordinary least square (OLS), stepwise regression (SR) and fixed effects panel regression models (FEPR) exhibited good fitness regardless of the cross-section or longitudinal models due to R2 beyond 0.9. The finding also discloses that EF and health were positively significant to SWB, while income was negatively significant to SWB. EF was an invert u-shaped link to SWB, which met the assumption of EKC. This research provided a model-driven quantitative method to address environmental impacts on people’s quality life of happiness, and opened shared doors for further research of carbon balance and circular economy.

Subjective quality of life of Slovak men with physical disabilities: An age categories differences

The objective of the study was to analyze and compare the subjective quality of life (S-QOL) of Slovak men with physical disabilities through satisfaction with the quality of life domains (QOLDs) and the overall quality of life (QOL) assessment. The sample comprised of men with physical disabilities (n = 132), divided into 4 age categories: 19–29 yrs. (n = 59); 30–44 yrs. (n = 26); 45–59 yrs. (n = 24) and over 60 yrs. (n = 23). The Subjective Quality of Life Analysis (S-QUA-L-A) and The World Health Organisation Quality of Life User Manual (WHOQOL User Manual) were used as primary research methods. The findings of this study confirm differences in S-QOL in one QOLD as well as in the overall QOL between two from four age categories of men with physical disabilities. The 19–29 yrs. old men were significantly more satisfied in their lives with the Physical health domains and declared significantly higher overall QOL compare to 45–59 yrs. men. There were no significant differences found in S-QOL between other pair comparisons of the age categories of men with physical disabilities. The highest satisfaction in all age categories of men was declared by the domains of Social relation and Physical health and the highest dissatisfaction by the Psychological health and Environment domains. It is necessary to continue this line of this research field with stress on exploring the ways of psychological health increase as an integral part of S-QOL in men with physical disabilities. Future research should focus on life indicators that saturate the Environment domain, which should be positively affected in mens’ life.