scholarly journals Sebaceoma of the External Auditory Canal

2020 ◽  
Vol 63 (12) ◽  
pp. 603-605
Author(s):  
Young Nam Kim ◽  
Jeong Hwan Choi ◽  
Chan Young Lee ◽  
Kyeong Mee Park
Keyword(s):  
Colon Cancer ◽  
External Auditory Canal ◽  
Rare Case ◽  
Benign Tumor ◽  
Mismatch Repair Genes ◽  
Internal Malignancy ◽  
Potential Association ◽  
History Of ◽  
Repair Genes ◽  
Visceral Malignancy

Sebaceomas of the external auditory canal (EAC) are extremely rare. The recognition of sebaceoma is important as this benign tumor can be be part of the spectrum of the Muir-Torre syndrome (MTS), which is associated with visceral malignancy and multiple adenomatous polyps. Proper histological identification is thus important for further investigation. We describe a rare case of a sebaceoma that was confined to the EAC. Subsequent immunohistochemical (IHC) staining analysis of the mismatch repair genes (MLH1, MSH2, MSH6, and PMS2) was needed to investigate MTS. Even though the patient has had the history of colon cancer, the result was negative. Otorhinolaryngologists should be aware of rare sebaceoma and its potential association with the internal malignancy, besides the limitation of IHC screening test.

scholarly journals Colorectal Metastasis from Ovarian Neoplasm Mimicking Primary Colon Cancer

2021 ◽  
pp. 41-46
Author(s):  
Anum Aqsa ◽  
Sami Droubi ◽  
Shivantha Amarnath ◽  
Fady Haddad ◽  
Liliane Deeb
Keyword(s):  
Colon Cancer ◽  
Previous History ◽  
Ovarian Neoplasm ◽  
Direct Visualization ◽  
Female Status ◽  
Internal Malignancy ◽  
Primary Colon Cancer ◽  
Primary Colon ◽  
History Of ◽  
Secondary Metastasis

Metastasis to the colon from another primary internal malignancy is an untypical and a seldom reported entity. Direct visualization during colonoscopy is considered the gold standard of diagnosis. Pathologic diagnosis with immunohistochemical staining is essential to differentiate primary colorectal malignancy from secondary metastasis to the colon. We, hereby, present a case of a 53-year-old female status-post resection of left-sided papillary serous ovarian neoplasm who presented 2 years later with a single rectosigmoid intraluminal ulcerative mass imitating a primary colon cancer. Biopsies of the mass were consistent with metastasis from her primary ovarian carcinoma. We believe this case is unique because of the rarity of ovarian cancer metastasizing to the colon intraluminally rather than through direct locoregional invasion. Furthermore, it highlights the importance of considering secondary metastasis in patients with previous history of another primary internal malignancy.

Human Mismatch Repair Genes and Their Association with Hereditary Non-Polyposis Colon Cancer

1994 ◽  
Vol 59 (0) ◽  
pp. 331-338 ◽  
Author(s):  
R.D. Kolodner ◽  
N.R. Hall ◽  
J. Lipford ◽  
M.F. Kane ◽  
M.R.S. Rao ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Mismatch Repair ◽  
Mismatch Repair Genes ◽  
Repair Genes

scholarly journals Intestinal obstruction after trauma laparotomy: a rare case due to colon cancer

2021 ◽  
Vol 6 (1) ◽  
pp. 25-27
Author(s):  
Byungjun Song ◽  
Pil Young Jung
Keyword(s):  
Colon Cancer ◽  
Intestinal Obstruction ◽  
Blunt Trauma ◽  
Large Bowel ◽  
Rare Case ◽  
Incarcerated Hernia ◽  
Tissue Adhesion ◽  
Common Causes ◽  
History Of ◽  
Bowel Neoplasm

The causes of intestinal obstruction are diverse with tissue adhesion, incarcerated hernia, and large bowel neoplasm being the most common causes. Cancer is not easy to diagnose in patients with a history of intestinal obstruction after the intraperitoneal operation following blunt trauma. Herein, we report the case of a patient who was diagnosed with colon cancer after undergoing adhesiolysis due to intestinal obstruction.

scholarly journals OSTEOMA OF EXTERNAL AUDITORY CANAL: CASE REPORT

2021 ◽  
Vol Volume 9 (upjohns/volume9/Issue2) ◽  
pp. 51-53
Author(s):  
Anshu Sood
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Temporal Bone ◽  
External Auditory Canal ◽  
Benign Tumor ◽  
Histopathological Examination ◽  
Otologic Surgery ◽  
Superior Part ◽  
History Of ◽  
Trauma Ct

ABSTRACT An osteoma of the external auditory canal is an uncommon benign tumor with an incidence estimated to be 0.05% of total otologic surgery. In head and neck, they most often arise in the frontoethmoidal region and rarely temporal bone. Osteomas usually asymptomatic and discovered incidentally. A 35 male presented with swelling in right posterior superior part of EAC, without any history of ear picking , swimming or trauma. CT temporal bone revealed a solitary osteoma, with was excised surgically. Histopathological examination confirmed Osteoma.

scholarly journals Muir-Torre Syndrome Presenting as Sebaceous Adenocarcinoma and Invasive MSH6-Positive Colorectal Adenocarcinoma

2016 ◽  
Vol 9 (1) ◽  
pp. 95-99 ◽  
Author(s):  
Sunil Tulpule ◽  
Hiyam Ibrahim ◽  
Mohamed Osman ◽  
Shoaib Zafar ◽  
Romana Kanta ◽  
...  
Keyword(s):  
Colorectal Adenocarcinoma ◽  
Surgical Intervention ◽  
Mismatch Repair Genes ◽  
Colorectal Carcinomas ◽  
Ascending Colon ◽  
Chemotherapy Treatment ◽  
Abdominal Ct ◽  
Internal Malignancy ◽  
Outpatient Chemotherapy ◽  
Repair Genes

Muir-Torre syndrome (MTS) is a rare genodermatosis, diagnosed by the presence of sebaceous neoplasms along with an internal malignancy, most commonly colorectal carcinomas. MTS is most commonly caused by microsatellite instabilities of the hMLH1 and hMSH2 mismatch repair genes, and is rarely caused by mutations of the hMSH6 gene. We describe the case of a 56-year-old male who presented with an enlarging mass on his back as well as hematochezia. The back mass was excised, and pathology confirmed microsatellite instability in MSH2 and MSH6. Abdominal CT and colonoscopy confirmed the presence of synchronous masses in the cecum, ascending colon, and the transverse colon. He refused any further workup or treatment, only to return 8 months later complaining of hematochezia and discomfort due to an enlarging mass protruding from the rectum. After consenting to surgical intervention, he agreed to outpatient chemotherapy treatment. The presence of sebaceous neoplasms should raise suspicion for the possibility of an associated internal malignancy.

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