Oral neoplasms in pickhandle barracuda Sphyraena jello from India

One hundred and forty-four Brazilian AIDS patients presenting with Kaposi’s sarcoma (KS) were evaluated with respect to the frequency of oral neoplasms and their clinical features. The majority of the patients were young male adults (age range: 21-40 years old), from which 11.1 % presented with oral KS (OKS) exclusively. Oral and skin lesions were associated in 25% of the cases, while only four patients showed association between oral and visceral KS; 49.3% of the cases were exclusively dermatological. The hard palate was the main site affected, followed by the oropharynx. The localization of KS was found to be similarly frequent in the tongue, gingiva and other sites of the oral mucosa. Candidosis was the prevailing fungal disease; in 20% of the cases it was restricted to the oral mucosa and in 80% it was systemic. No high frequency of paracoccidioidomicosis and cryptococcosis was detected. The prevailing bacterial disease was Tuberculosis and there was only one case of syphilis. Among the viral diseases, the most frequently detected was herpes simplex, followed by molusco contagiosum, condiloma acuminatum and cytomegaloviroses at lower frequencies. Pneumonia caused by Pneumocystes carinii and toxoplasmosis were also identified. The authors emphasise the importance of oral examination in HIV-infected patients bearing in mind several aspects related especially to KS, and stress the need for an interdisciplinary team in the management of these patients, in order to provide better quality of life as well as rapid diagnosis and treatment.

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Topical application of Photofrin for photodynamic diagnosis of oral neoplasms

CLEO/Pacific Rim 2003. The 5th Pacific Rim Conference on Lasers and Electro-Optics (IEEE Cat. No.03TH8671) ◽

10.1109/cleopr.2003.1277136 ◽

2004 ◽

Author(s):

Chun-Yuan Huang ◽

Cheng-Jen Chang ◽

Pei-Shu Hwang ◽

Muh-Shi Lin ◽

P. Wilder-Smith

Keyword(s):

Topical Application ◽

Photodynamic Diagnosis ◽

Oral Neoplasms

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Comparative pathology of oral neoplasms

Oral Surgery Oral Medicine Oral Pathology ◽

10.1016/0030-4220(53)90221-7 ◽

1953 ◽

Vol 6 (9) ◽

pp. 1078-1094 ◽

Cited By ~ 24

Author(s):

Hans G. Schlumberger

Keyword(s):

Comparative Pathology ◽

Oral Neoplasms

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Oral Neoplasms in HIV Positive Patient

Advances in HIV and AIDS Control ◽

10.5772/intechopen.78764 ◽

2018 ◽

Author(s):

Kelly Cristine Tarquinio Marinho ◽

Elcio Magdalena Giovani ◽

Camila Correia dos Santos ◽

Rodolfo Georgevich Neto

Keyword(s):

Positive Patient ◽

Hiv Positive ◽

Oral Neoplasms

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Cyclooxygenase-2 Expression Is Related With Localization, Proliferation, and Overall Survival in Canine Melanocytic Neoplasms

Veterinary Pathology ◽

10.1177/0300985810396517 ◽

2011 ◽

Vol 48 (6) ◽

pp. 1204-1211 ◽

Cited By ~ 12

Author(s):

C. M. Martínez ◽

C. Peñafiel-Verdú ◽

M. Vilafranca ◽

G. Ramírez ◽

M. Méndez-Gallego ◽

...

Keyword(s):

Overall Survival ◽

Mitotic Index ◽

Tumor Location ◽

Cyclooxygenase 2 ◽

Ki 67 ◽

Melanocytic Tumors ◽

Oral Neoplasms ◽

Survival Frequency ◽

Cox 2 ◽

Proliferative Indices

A direct relationship has been firmly established between cyclooxygenase-2 (COX-2) expression and malignant behavior in human melanoma. This report examines the relationship between COX-2 expression and tumor location, mitotic and proliferative indices, degree of T CD3+ lymphocyte infiltration, overall survival, and frequency of recurrence and metastasis of 57 melanocytic tumors (25 oral and 32 cutaneous). COX-2 was highly or moderately expressed in 88% of oral neoplasms (22 of 25), whereas for their cutaneous counterparts, COX-2 expression was low or insignificant in 75% of cases (24 of 32). High and moderate COX-2 expression levels were observed in 73% of melanocytic tumors with a mitotic index ≥ 3 per 10 high-power fields (26 of 36), whereas in 81% of tumors with a mitotic index < 3 (17 of 21), expression was mild or absent. There were 41 cases with known clinical outcomes; of those showing high, moderate, and mild COX-2 expression, 83.3% (10 of 12), 37.5% (3 of 8), and 25% (2 of 8) died, respectively, whereas 100% of animals showing no COX-2 expression (13 of 13) were still alive at the last follow-up. COX-2 expression was statistically correlated with tumor location, mitotic and percentage Ki-67 proliferative indices, and overall survival, frequency of neoplastic recurrence and metastasis. Regression analysis also showed disease-specific predictive value for COX-2 expression for subjects with melanocytic neoplasms. Additionally, only high COX-2 expression showed significant differences in overall survival, in comparison with moderate, mild, or absent expression. These results suggest that high COX-2 expression may be considered a prognostic biomarker and potentially as a target for therapeutic and preventive strategies in canine melanocytic neoplasms.

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Topical Application of Photofrin® for Oral Neoplasms in Animal

Optical and Quantum Electronics ◽

10.1007/s11082-005-4215-4 ◽

2005 ◽

Vol 37 (13-15) ◽

pp. 1353-1365 ◽

Cited By ~ 4

Author(s):

Cheng-Jen Chang ◽

Muh-Shi Lin ◽

Pei-Shu Hwang ◽

Sally M. H. Cheng

Keyword(s):

Topical Application ◽

Oral Neoplasms

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Naturally Occurring Orocutaneous Papillomas and Carcinomas of Brown Bullheads (Ictalurus nebulosus) in New York State

Veterinary Pathology ◽

10.1177/030098589403100102 ◽

1994 ◽

Vol 31 (1) ◽

pp. 8-18 ◽

Cited By ~ 25

Author(s):

F. M. Poulet ◽

M. J. Wolfe ◽

J. M. Spitsbergen

Keyword(s):

New York ◽

New York State ◽

Enamel Organ ◽

Diagnostic Study ◽

Apparent Difference ◽

York State ◽

Dental Plate ◽

Ictalurus Nebulosus ◽

Significant Difference ◽

Oral Neoplasms

Ninety-four brown bullheads ( Ictalurus nebulosus) with spontaneous orocutaneous neoplasms (papillomas and carcinomas) were studied grossly and by light microscopy. Of these 94 fish, 71 were selected from 505 fish examined macroscopically during field surveys and 23 were selected from those submitted for diagnostic study. Fish with neoplasms came from 17 locations throughout New York State: Buffalo River, Canaan Lake, Cazenovia Lake, Delta Lake, Fort Pond, Greenwood Lake, Hudson River, Lake George, Lake Tiorati, Lincoln Hall Pond, Lincoln Pond, Oneida Lake, Onondaga Lake, Rutland Pond, Salmon River, Silver Stream Reservoir, and Swan Lake. The prevalence varied from 0 to 100%. Multiple neoplasms were more common (84/94, 89%) than solitary ones (10/94, 11%). In order of decreasing frequency, neoplasms arose on the head, especially the ventral aspect, the lower dental plate, the upper dental plate, the trunk, the barbels, the fins, the tongue, and the tail. Of the 38/94 brown bullheads (40%) with tumors in both upper and lower lips and dental plates, 24/38 (63%) had the tumors in opposition. Macroscopically, soft, pink or yellowish papillary masses protruded above the normal epithelial surfaces. Histologically, cutaneous and oral neoplasms originated from the morphologically similar Malpighian epithelial cells of the surface epithelia and from the outer cells of the enamel organ. Based on histopathologic criteria, cutaneous and oral neoplasms were considered the same disease in different anatomic locations. No apparent difference in biologic behavior was noted between cutaneous and oral neoplasms. The lesions apparently progressed from benign papilloma to locally invasive carcinoma (28/94, 30%). Neoplastic emboli were seen in one case, and no metastases were detected. There was no statistically significant difference between the susceptibility of males (20/57, 35%) and females (6/26, 23%) to carcinomas. An apparent correlation was noted between a higher frequency of malignant tumors and longer body size (3/ 13 fish [23%] <30 cm, 17/54 fish [31%] 30–34 cm, and 7/18 fish [39%] >34 cm).

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