Initial occurrence, ontogenic distribution-shifts and advection of Nemopilema nomurai (Scyphozoa: Rhizostomeae) in Liaodong Bay, China, from 2005-2015

Jellyfish venom is well known for its local skin toxicities and various lethal accidents. The main symptoms of local jellyfish envenomation include skin lesions, burning, prickling, stinging pain, red, brown, or purplish tracks on the skin, itching, and swelling, leading to dermonecrosis and scar formation. However, the molecular mechanism behind the action of jellyfish venom on human skin cells is rarely understood. In the present study, we have treated the human HaCaT keratinocyte with Nemopilema nomurai jellyfish venom (NnV) to study detailed mechanisms of actions behind the skin symptoms after jellyfish envenomation. Using two-dimensional gel electrophoresis (2-DE) and matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF/MS), cellular changes at proteome level were examined. The treatment of NnV resulted in the decrease of HaCaT cell viability in a concentration-dependent manner. Using NnV (at IC50), the proteome level alterations were determined at 12 h and 24 h after the venom treatment. Briefly, 70 protein spots with significant quantitative changes were picked from the gels for MALDI-TOF/MS. In total, 44 differentially abundant proteins were successfully identified, among which 19 proteins were increased, whereas 25 proteins were decreased in the abundance levels comparing with their respective control spots. DAPs involved in cell survival and development (e.g., Plasminogen, Vinculin, EMILIN-1, Basonuclin2, Focal adhesion kinase 1, FAM83B, Peroxisome proliferator-activated receptor-gamma co-activator 1-alpha) decreased their expression, whereas stress or immune response-related proteins (e.g., Toll-like receptor 4, Aminopeptidase N, MKL/Myocardin-like protein 1, hypoxia up-regulated protein 1, Heat shock protein 105 kDa, Ephrin type-A receptor 1, with some protease (or peptidase) enzymes) were up-regulated. In conclusion, the present findings may exhibit some possible key players during skin damage and suggest therapeutic strategies for preventing jellyfish envenomation.

Download Full-text

Predicted shifts of groundfish distribution in the Eastern Bering Sea under climate change, with implications for fish populations and fisheries management

ICES Journal of Marine Science ◽

10.1093/icesjms/fsaa215 ◽

2020 ◽

Author(s):

Christopher N Rooper ◽

Ivonne Ortiz ◽

Albert J Hermann ◽

Ned Laman ◽

Wei Cheng ◽

...

Keyword(s):

Bering Sea ◽

Marine Species ◽

Species Distribution Modelling ◽

Fish Populations ◽

Trawl Survey ◽

Climate Scenarios ◽

Important Species ◽

Eastern Bering Sea ◽

Northern Latitudes ◽

Distribution Shifts

Abstract Climate-related distribution shifts for marine species are, in general, amplified in northern latitudes. The objective of this study was to predict future distributions of commercially important species in the eastern Bering Sea under six climate scenarios, by incorporating predictions of future oceanographic conditions. We used species distribution modelling to determine potential distribution changes in four time periods (2013–2017, 2030–2039, 2060–2069, and 2090-2099) relative to 1982–2012 for 16 marine fish and invertebrates. Most species were predicted to have significant shifts in the centre of gravity of the predicted abundance, the area occupied, and the proportion of the predicted abundance found in the standard bottom trawl survey area. On average the shifts were modest, averaging 35.2 km (ranging from 1 to 202 km). There were significant differences in the predicted trend for distribution metrics among climate scenarios, with the most extensive changes in distribution resulting from Representative Concentration Pathway 8.5 climate scenarios. The variability in distributional shifts among years and climate scenarios was high, although the magnitudes were low. This study provides a basis for understanding where fish populations might expand or contract in future years. This will provide managers’ information that can help guide appropriate actions under warming conditions.

Download Full-text