scholarly journals Kinetics of Manganese Absorption in Ligated Small Intestinal Segments of Broilers

2008 ◽  
Vol 87 (12) ◽  
pp. 2596-2604 ◽  
Author(s):  
S.P. Bai ◽  
L. Lu ◽  
X.G. Luo ◽  
B. Liu
2016 ◽  
Vol 94 (8) ◽  
pp. 3312-3320 ◽  
Author(s):  
S. B. Liu ◽  
Y. X. Hu ◽  
X. D. Liao ◽  
L. Lu ◽  
S. F. Li ◽  
...  

2016 ◽  
Vol 94 (12) ◽  
pp. 5219-5229 ◽  
Author(s):  
L. Y. Zhang ◽  
X. D. Liao ◽  
L. Y. Zhang ◽  
L. Lu ◽  
X. G. Luo

1975 ◽  
Vol 229 (5) ◽  
pp. 1365-1370 ◽  
Author(s):  
JW Fara ◽  
KS Madden

The relative blood flow distribution within the small intestine of anesthetized cats was investigated during resting conditions and when superior mesenteric blood flow was increased 15--85% by the intravenous infusion of secretin, cholecystokinin (CCK), or isoproterenol. Radioactive microspheres of 15 mum diameter were injected into the superior mesenteric artery and shortly thereafter intestinal segments were removed and dissected into mucosal, submucosal, and muscularis fractions. Tissue weights and the radioactivity of each were determined. During secretin-induced mesenteric vasodilatation there was a significant redistribution of blood away from the jejunal mucosa to the submucosa. During CCK and isoproterenol infusions there were significant increases in mucosal and decreases in submucosal blood flow. No significant changes were observed in muscularis flow. There was no apparent relationship between the percent increase in SMBF and the relative blood flow distribution changes observed. The results indicate that while secretin, CCK, and isoproterenol increase superior mesenteric blood flow, they also affect blood flow distribution within the mucosa and submucosa.


2004 ◽  
Vol 10 (7) ◽  
pp. 749-753 ◽  
Author(s):  
Brigid Joseph ◽  
Ekaterine Berishvili ◽  
Daniel Benten ◽  
Vinay Kumaran ◽  
Ekaterine Liponava ◽  
...  

1989 ◽  
Vol 26 (5) ◽  
pp. 376-385 ◽  
Author(s):  
A. C. Huber ◽  
R. H. Yolken ◽  
L. C. Mader ◽  
J. D. Strandberg ◽  
S. L. Vonderfecht

Suckling rats were inoculated with a group B rotavirus to determine the progression of the morphologic changes induced in the intestine by this virus. Several changes were observed by light microscopy 1 day after viral inoculation: shortening of small intestinal villi, villous epithelial necrosis, and villous epithelial syncytia. The lesions were most often present in the distal small intestine, although other small intestinal segments were affected to a lesser degree. By day 3 post-inoculation, epithelial necrosis, and syncytia were no longer present; however, the villous epithelium was disorganized and irregularly vacuolated, and intestinal crypt epithelium was hyperplastic. Alterations in villous height to crypt depth ratios were present in portions of the small intestine for the remainder of the 12-day study period. Epithelial syncytia appeared to form by the breakdown of the lateral interdigitating membranes of the absorptive villous epithelium. Viral particles, abundant in the syncytia, appeared to form from amorphous or reticular arrays of viral precursor material. Group B rotaviral antigens, as detected by indirect immunofluorescence, were present in large amounts in the small intestinal villous epithelium only on the first day after viral inoculation. These studies show that two important diagnostic features of group B rotaviral infections of rats, epithelial syncytia and viral antigen as determined by immunofluorescence, are present only on the first day of disease. These findings should be taken into consideration when attempting to diagnose disease induced by this agent.


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 178-179
Author(s):  
Jiali Chen ◽  
Min Wang ◽  
Tania L Archbold ◽  
Weijun Wang ◽  
Wenyi Fan ◽  
...  

Abstract Understanding roles of prescribed in-feed therapeutic multi-antimicrobials in affecting the small intestinal terminal starch digestive enzyme activity in improving weaning pig growth and feed utilization may shed light on developing novel alternative strategies to reduce uses of antimicrobials. A total of 125 crossbred barrows, weaned on d 19–21 with an average initial BW of 6.9 ± 0.1 kg, were randomly assigned to two corn, SBM and dried whey powder based diets for 21 d according to a randomized complete block design. The multi-antimicrobial diet was supplemented with aureomycin 220, tiamulin 31.2 and ZnO 2,358 at mg/kg diet. The growth performances including final BW (control, 13.9 ± 0.2 vs. antimicrobials, 15.0 ± 0.2 kg), ADG (control, 0.307 ± 0.009 vs. antimicrobials, 0.355 ± 0.009 kg/d), ADFI (control, 0.425 ± 0.012 vs. antimicrobials, 0.455 ± 0.013 kg/d) and F:G (control, 1.39 ± 0.03 vs. antimicrobials, 1.28 ± 0.03 kg/kg) were improved (P < 0.05; n = 25 pens; 5 barrows/pen) compared to the non-antimicrobial control diet. The combined enzyme kinetics of the jejunal and the ileal maltase-glucoamylase (MGA) and sucrase-isomaltase (SI) activity were determined with the jejunal and the ileal homogenates by using maltose (0–60 mM in incubation mixture). The combined jejunal and the ileal MGA-SI affinity Km values and the combined jejunal MGA-SI maximal activity Vmax values were not different (P > 0.05) between the two diet groups. However, the combined ileal MGA-SI Vmax (nmol·mg protein-1·min-1) was increased in the antimicrobial diet (P < 0.05; control, 125.6 ± 10.84, n = 13 pigs vs. antimicrobials, 170.8 ± 12.15, n = 11 pigs) in comparison with the control diet. The Pearson’s correlation analyses revealed that the combined ileal MGA-IS Vmax of hydrolyzing maltose was associated with ADG (P = 0.0669; r = 0.38; n = 24 pigs) and feed efficiency (F:G; P < 0.05; r = -0.53; n = 24 pigs). Our results suggest that in-feed therapeutic multi-antimicrobials could improve the distal small intestinal terminal starch digestive enzyme MGA-SI activity, thus improving growth and feed efficiency in weaning pigs.


2021 ◽  
Vol 196 (2) ◽  
Author(s):  
Junru Wang ◽  
Sarita Garg ◽  
Reid D. Landes ◽  
Liya Liu ◽  
Qiang Fu ◽  
...  

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