The Potassium Channel KCa3.1 Represents a Valid Pharmacological Target for Astrogliosis-Induced Neuronal Impairment in a Mouse Model of Alzheimer’s Disease

Frontiers in Pharmacology ◽

10.3389/fphar.2016.00528 ◽

2017 ◽

Vol 7 ◽

Author(s):

Tianjiao Wei ◽

Mengni Yi ◽

Wen Gu ◽

Lina Hou ◽

Qin Lu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Potassium Channel ◽

Model Of Alzheimer’S Disease ◽

Pharmacological Target

Download Full-text

Changes in phagocytosis and potassium channel activity in microglia of 5xFAD mice indicate alterations in purinergic signaling in a mouse model of Alzheimer's disease

Neurobiology of Aging ◽

10.1016/j.neurobiolaging.2017.05.027 ◽

2017 ◽

Vol 58 ◽

pp. 41-53 ◽

Author(s):

Stefan Wendt ◽

Meron Maricos ◽

Natascha Vana ◽

Niklas Meyer ◽

Dilansu Guneykaya ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Potassium Channel ◽

Purinergic Signaling ◽

Channel Activity ◽

Model Of Alzheimer’S Disease ◽

Potassium Channel Activity

Download Full-text

Cognitive recovery by chronic activation of the large-conductance calcium-activated potassium channel in a mouse model of Alzheimer's disease

Neuropharmacology ◽

10.1016/j.neuropharm.2014.12.033 ◽

2015 ◽

Vol 92 ◽

pp. 8-15 ◽

Author(s):

Li Wang ◽

Huicong Kang ◽

Yongzhi Li ◽

Yuan Shui ◽

Ryo Yamamoto ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Potassium Channel ◽

Cognitive Recovery ◽

Model Of Alzheimer’S Disease ◽

Chronic Activation ◽

Calcium Activated Potassium Channel

Download Full-text

The effects of a neuroligin-1-derived peptide on behaviour in the 5XFAD mouse model of Alzheimer's disease

10.26226/morressier.5785edc6d462b80296c991f6 ◽

2016 ◽

Author(s):

Katrin Sonn

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Model Of Alzheimer’S Disease ◽

Download Full-text

Effects of Interleukin-6 trans-signalling in a mouse model of Alzheimer’s disease and high fat diet-induced obesity

10.26226/morressier.5b681764b56e9b005965c045 ◽

2018 ◽

Author(s):

Anna Escrig Monfort

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Interleukin 6 ◽

High Fat Diet ◽

High Fat ◽

Diet Induced Obesity ◽

Model Of Alzheimer’S Disease

Download Full-text

Faculty Opinions recommendation of Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020559.235469 ◽

2004 ◽

Author(s):

Karl-Peter Giese

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Procedural Learning ◽

Model Of Alzheimer’S Disease

Download Full-text

Faculty Opinions recommendation of Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1099453.555719 ◽

2008 ◽

Author(s):

Massimo Pandolfo

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Model Of Alzheimer’S Disease ◽

Local Toxicity ◽

Rapid Appearance

Download Full-text

Faculty Opinions recommendation of Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1123163.580293 ◽

2008 ◽

Author(s):

Geneviève Dupont

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Plaques ◽

Model Of Alzheimer’S Disease

Download Full-text

Faculty Opinions recommendation of Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4693956.4576054 ◽

2010 ◽

Author(s):

Francine Benes ◽

Barbara Gisabella

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Histone Deacetylases ◽

Memory Deficits ◽

Contextual Memory ◽

Model Of Alzheimer’S Disease ◽

Download Full-text

Faculty Opinions recommendation of Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5594956.5560054 ◽

2010 ◽

Author(s):

Riqiang Yan

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Beta Amyloid ◽

Transgenic Mouse Model ◽

Amyloid Deposition ◽

Gamma Secretase ◽

Model Of Alzheimer’S Disease

Download Full-text

Faculty Opinions recommendation of Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717977209.793470743 ◽

2013 ◽

Author(s):

Matt Kaeberlein

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

Download Full-text