scholarly journals The Prognostic Significance of Neutrophil to Lymphocyte Ratio (NLR), Monocyte to Lymphocyte Ratio (MLR) and Platelet to Lymphocyte Ratio (PLR) on Long-Term Survival in Off-Pump Coronary Artery Bypass Grafting (OPCAB) Procedures

Biology ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 34
Author(s):  
Tomasz Urbanowicz ◽  
Anna Olasińska-Wiśniewska ◽  
Michał Michalak ◽  
Michał Rodzki ◽  
Anna Witkowska ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Artery Bypass ◽  
Multivariable Analysis ◽  
Bypass Grafting ◽  
Off Pump ◽  
Lymphocyte Ratio ◽  
Pump Coronary Artery Bypass ◽  
Long Term Mortality

Background: Cardiovascular diseases, apart from commonly known risk factors, are related to inflammation. There are several simple novel markers proposed to present the relation between inflammatory reactions activation and atherosclerotic changes. They are easily available from whole blood count and include neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), and platelets to lymphocyte ratio (PLR). The RDW results were excluded from the analysis. Method and results: The study based on retrospective single-centre analysis of 682 consecutive patients (131 (19%) females and 551 (81%) males) with median age of 66 years (60–71) who underwent off-pump coronary artery bypass grafting (OPCAB) procedure. During the median 5.3 +/− 1.9 years follow-up, there was a 87% cumulative survival rate. The laboratory parameters including preoperative MLR > 0.2 (HR 2.46, 95% CI 1.33–4.55, p = 0.004) and postoperative NLR > 3.5 (HR 1.75, 95% CI 1.09–2.79, p = 0.019) were found significant for long-term mortality prediction in multivariable analysis. Conclusion: Hematological indices NLR and MLR can be regarded as significant predictors of all-cause long-term mortality after OPCAB revascularization. Multivariable analysis revealed preoperative values of MLR > 0.2 and postoperative values of NLR > 3.5 as simple, reliable factors which may be applied into clinical practice for meticulous postoperative monitoring of patients in higher risk of worse prognosis.

scholarly journals Does Age at Operation Influence the Short- and Long-Term Outcomes of Off-Pump Coronary Artery Bypass Grafting?

2015 ◽  
Vol 79 (10) ◽  
pp. 2177-2185 ◽  
Author(s):  
Suguru Ohira ◽  
Kiyoshi Doi ◽  
Satoshi Numata ◽  
Sachiko Yamazaki ◽  
Tsunehisa Yamamoto ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Long Term Outcomes ◽  
Off Pump ◽  
Short And Long Term ◽  
Pump Coronary Artery Bypass

scholarly journals Mid-term and long-term results of off-pump coronary artery bypass grafting for patients with left main disease

2015 ◽  
Vol 21 (3) ◽  
pp. 179-184
Author(s):  
Tomohiro Mizuno ◽  
Keishi Oi ◽  
Masafumi Yashima ◽  
Tsuyoshi Hachimaru ◽  
Daiju Watanabe ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Artery Bypass ◽  
Long Term Results ◽  
Bypass Grafting ◽  
Left Main ◽  
Left Main Disease ◽  
Off Pump ◽  
Pump Coronary Artery Bypass

scholarly journals Long Term Outcomes of The Off-Pump and On-Pump Coronary Artery Bypass Grafting In A High-Volume Center

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Milos Matkovic ◽  
Vladimir Tutus ◽  
Ilija Bilbija ◽  
Jelena Milin Lazovic ◽  
Marko Savic ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Artery Bypass ◽  
High Volume ◽  
Bypass Grafting ◽  
Long Term Outcomes ◽  
Off Pump ◽  
High Volume Center ◽  
Pump Coronary Artery Bypass

Long-Term Clinical Outcome of the Symmetry Aortic Connector System in Off-Pump Coronary Artery Bypass Grafting

2012 ◽  
Vol 61 (08) ◽  
pp. 669-675
Author(s):  
M. Mostafa Mokhles ◽  
Sander Bramer ◽  
Albert van Straten ◽  
Joost ter Woorst ◽  
Jos Maessen ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Clinical Outcome ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Off Pump ◽  
Pump Coronary Artery Bypass ◽  
Aortic Connector

scholarly journals Results of off-pump coronary artery bypass grafting with off-pump first strategy in octogenarian

2021 ◽  
Author(s):  
Hideki Kitamura ◽  
Mototsugu Tamaki ◽  
Yasuhiko Kawaguchi ◽  
Yasuhide Okawa
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Long Term Results ◽  
Bypass Grafting ◽  
Artery Bypass Grafting ◽  
Off Pump ◽  
Pump Coronary Artery Bypass

Background and aim: Ischemic heart disease is the leading cause of death around the world. Coronary artery bypass grafting offers efficient surgical revascularization for ischemic disease. Both on- or off-pump coronary artery bypass methods provide promising results to octogenarians, once complete vascularization is achieved. However, off-pump bypass requires a certain level of experience to achieve sufficient results. We have applied an off-pump coronary artery bypass-first strategy to all generations since 2008. This study investigated early and long-term results of surgical revascularization for octogenarians by a team with an off-pump-first strategy. Methods: All cases of isolated coronary artery bypass grafting performed since 2008 were identified and divided into a young group (age <80 years) and an old group (age >=80 years). Peri-operative results were investigated retrospectively in both groups and long-term results for the old group were assessed. Results: Among the 707 patients, 97% underwent off-pump bypass, and 94 cases were classified to the old group. Distal anastomoses and ventilator time were identical between groups (young vs. old: 3.3 vs. 3.2; 3.7 h vs. 3.7 h). In-hospital death rates were 0.5% and 0% in the young and old groups, respectively. With a mean follow-up of 1318 days, actual 1-, 3-, and 5-year survival rates for octogenarians were 92.1%, 81.2% and 68.3%, respectively. Nearly half of the patients reached their nineties, which was close to the life expectancy of the national general octogenarian. Conclusions: An experienced team with an off-pump-first strategy could provide valid therapeutic options for octogenarians.

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