scholarly journals The Role of Positron Emission Tomography/Computed Tomography (PET/CT) for Staging and Disease Response Assessment in Localized and Locally Advanced Pancreatic Cancer

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4155
Author(s):  
Michele Ghidini ◽  
Marta Vuozzo ◽  
Barbara Galassi ◽  
Paola Mapelli ◽  
Virginia Ceccarossi ◽  
...  

Pancreatic Cancer (PC) has a poor prognosis, with a 5-year survival rate of only 9%. Even after radical surgical procedures, PC patients have poor survival rates, with a high chance of relapse (70–80%). Imaging is involved in all aspects of the clinical management of PC, including detection and characterization of primary tumors and their resectability, assessment of vascular, perineural and lymphatic invasion and detection of distant metastases. The role of Positron Emission Tomography/Computed Tomography (PET/CT) in detecting PC is still controversial, with the international guidelines not recommending its routine use. However, in resectable PC, PET/CT may play a role in assessing PC stage and grade and potential resectability after neoadjuvant treatment. Quantitative image analysis (radiomics) and new PET/CT radiotracers account for future developments in metabolic imaging and may further improve the relevance of this technique in several aspects of PC. In the present review, the current state of the art and future directions of PET/CT in resectable PC are presented.

2022 ◽  
Vol 12 (01) ◽  
pp. 11-20
Author(s):  
Balireddy Vasundhara ◽  
Pottumuthu Hemalatha ◽  
Pakalapati Satya Sarath Kumar Raju

2020 ◽  
Vol 35 (1_suppl) ◽  
pp. 37-41
Author(s):  
Laura Evangelista

The utility of positron emission tomography (PET) for the evaluation of response to immunotherapy has been considered a hot topic, particularly in the last 2 to 3 years. Different experiences have been collected in clinical practice, with 18F-Fluorodeoxyglucose (FDG) PET/computed tomography (CT), particularly in patients affected by lymphoma, malignant melanoma, and lung cancer. It has been tested in different settings of disease, from the prediction to the prognosis relative to the response to immunotherapy. In the present mini-review, some evidence is reported about the role of FDG PET/CT in patient candidates to or treated with immunotherapy.


2015 ◽  
Vol 25 (4) ◽  
pp. 645-649 ◽  
Author(s):  
Bryony Simcock ◽  
Kailash Narayan ◽  
Elizabeth Drummond ◽  
David Bernshaw ◽  
Elizabeth Wells ◽  
...  

ObjectiveThe optimal method of assessing disease distribution in endometrial cancer is widely debated. Knowledge of disease distribution assists in planning adjuvant radiotherapy; in this study we used positron emission tomography/computed tomography (PET/CT) to assess disease distribution before radiotherapy.MethodsSeventy-three consecutive patients referred to the Peter MacCallum Cancer Centre for adjuvant radiotherapy for endometrial cancer, with either high-risk disease after a hysterectomy or recurrent disease, had a PET/CT before treatment. The findings on PET/CT and clinical course were recorded.ResultsPET/CT found additional disease in 35% of postoperative patients, changing planned treatment in 31%. In the group with known recurrence, additional disease was found in 72%, changing management in 36%.ConclusionsPET/CT is a valuable tool for planning radiotherapy in endometrial cancer.


2014 ◽  
Vol 46 (8) ◽  
pp. 744-749 ◽  
Author(s):  
Stefano Crippa ◽  
Matteo Salgarello ◽  
Silvia Laiti ◽  
Stefano Partelli ◽  
Paola Castelli ◽  
...  

2014 ◽  
Vol 13 (1) ◽  
pp. e394-e394a
Author(s):  
O. Kaygisiz ◽  
G. Ozmerdiven ◽  
Y. Kordan ◽  
B. Coskun ◽  
H. Vuruskan ◽  
...  

2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
Onur KAYGISIZ ◽  
Gokhun Ozmerdiven ◽  
Yakup Kordan ◽  
Burhan Coskun ◽  
Hakan Vuruskan ◽  
...  

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