The Role of Positron Emission Tomography/Computed Tomography in Management and Prediction of Survival in Pancreatic Cancer

2016 ◽  
Vol 40 (1) ◽  
pp. 142-151 ◽  
Author(s):  
Pratyusha Nunna ◽  
Sara Sheikhbahaei ◽  
Sejin Ahn ◽  
Brenda Young ◽  
Rathan M. Subramaniam
2014 ◽  
Vol 46 (8) ◽  
pp. 744-749 ◽  
Author(s):  
Stefano Crippa ◽  
Matteo Salgarello ◽  
Silvia Laiti ◽  
Stefano Partelli ◽  
Paola Castelli ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 4155
Author(s):  
Michele Ghidini ◽  
Marta Vuozzo ◽  
Barbara Galassi ◽  
Paola Mapelli ◽  
Virginia Ceccarossi ◽  
...  

Pancreatic Cancer (PC) has a poor prognosis, with a 5-year survival rate of only 9%. Even after radical surgical procedures, PC patients have poor survival rates, with a high chance of relapse (70–80%). Imaging is involved in all aspects of the clinical management of PC, including detection and characterization of primary tumors and their resectability, assessment of vascular, perineural and lymphatic invasion and detection of distant metastases. The role of Positron Emission Tomography/Computed Tomography (PET/CT) in detecting PC is still controversial, with the international guidelines not recommending its routine use. However, in resectable PC, PET/CT may play a role in assessing PC stage and grade and potential resectability after neoadjuvant treatment. Quantitative image analysis (radiomics) and new PET/CT radiotracers account for future developments in metabolic imaging and may further improve the relevance of this technique in several aspects of PC. In the present review, the current state of the art and future directions of PET/CT in resectable PC are presented.


2021 ◽  
Vol 135 (11) ◽  
pp. 970-975
Author(s):  
A Rovira ◽  
J Tornero ◽  
M Taberna ◽  
M Oliva ◽  
R Montal ◽  
...  

AbstractObjectiveThis study aimed to evaluate the effectiveness of computed tomography and positron emission tomography-computed tomography prior to salvage surgery after head and neck carcinoma treated with bioradiotherapy and to look at the role of neck dissection in this setting.MethodThis study was a retrospective chart review of a series of consecutive patients with locally advanced head and neck squamous cell carcinoma treated with bioradiotherapy. Radiological and pathological stages were compared to evaluate the accuracy of computed tomography and positron emission tomography-computed tomography in detecting occult neck metastasis in the context of recurrence of primary tumour. In order to assess the impact of neck dissection on survival, Kaplan–Meier survival curves after salvage surgery with and without neck dissection were derived.ResultsA total of 268 patients were identified, of which 22 underwent salvage surgery. The negative predictive value of computed tomography and positron emission tomography-computed tomography was excellent. Neck dissection did not represent an improvement on overall, disease specific and regional recurrence free survival (p = 0.67, p = 0.91 and p = 0.62, respectively) amongst clinically and radiologically negative necks.ConclusionConservative treatment of the neck should be considered when dealing with patients with primary site recurrence or persistent disease after bioradiotherapy without evidence of neck disease.


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