scholarly journals Hollow-Shell-Structured Mesoporous Silica-Supported Palladium Catalyst for an Efficient Suzuki-Miyaura Cross-Coupling Reaction

Catalysts ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 582
Author(s):  
Abdulelah Taher Ali Mohammed ◽  
Lijian Wang ◽  
Ronghua Jin ◽  
Guohua Liu ◽  
Chunxia Tan
Keyword(s):  
Chemical Engineering ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cost Effective ◽  
Active Species ◽  
Palladium Acetate ◽  
Hollow Shell ◽  
Electron Microscopies ◽  
Cross Coupling Reaction ◽  
The Cost

The construction of a high stability heterogeneous catalyst for privileged common catalysis is a benefit in regard to reuse and separation. Herein, a palladium diphenylphosphine-based hollow-shell-structured mesoporous catalyst (HS@PdPPh2@MSN) was prepared by immobilizing bis((diphenylphosphino)ethyltriethoxysilane)palladium acetate onto the inner wall of a mesoporous organicsilicane hollow shell, whose surface was protected by a –Si(Me)3 group. Electron microscopies confirmed its hollow-shell-structure, and structural analyses and characterizations revealed its well-defined single-site active species within the silicate network. As presented in this study, the newly constructed HS@PdPPh2@MSN enabled an efficient Suzuki-Miyaura cross-coupling reaction for varieties of substrates with up to 95% yield in mild conditions. Meanwhile, it could be reused at least five times with good activity, indicating its excellent stability and recyclability. Furthermore, the cost-effective and easily synthesized HS@PdPPh2@MSN made it a good candidate for employment in fine chemical engineering.

Nature of the Copper-Oxide-Mediated C–S Cross-Coupling Reaction: Leaching of Catalytically Active Species from the Metal Oxide Surface

ACS Catalysis ◽  
2016 ◽  
Vol 6 (6) ◽  
pp. 3637-3643 ◽  
Author(s):  
Yulia S. Panova ◽  
Alexey S. Kashin ◽  
Maxim G. Vorobev ◽  
Evgeniya S. Degtyareva ◽  
Valentine P. Ananikov
Keyword(s):  
Metal Oxide ◽  
Copper Oxide ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Active Species ◽  
Oxide Surface ◽  
Metal Oxide Surface ◽  
Cross Coupling Reaction ◽  
Catalytically Active

Anchored Pd(0) Nanoparticles on Synthetic Talc for the Synthesis of Biaryls and a Precursor of Angiotensin II Inhibitors

Synthesis ◽  
2020 ◽  
Author(s):  
Nelson Luís C. Domingues ◽  
Beatriz F. dos Santos ◽  
Beatriz A. L. da Silva ◽  
Aline R. de Oliveira ◽  
Maria H. Sarragiotto
Keyword(s):  
Angiotensin Ii ◽  
Palladium Catalysts ◽  
Rational Design ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cost Effective ◽  
Significant Loss ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed ◽  
Short Time

AbstractThe palladium-catalyzed Suzuki–Miyaura cross-coupling reaction is one of the most important and efficient reactions to prepare a variety of organic compounds, including biaryls. Despite the overwhelming number of reports related to this topic, some methodological difficulties persist in terms of catalyst handling, recovery, and reuse, as well as the reaction media. This work reports the rational design of new, efficient, cost-effective, and reusable palladium catalysts supported on synthetic talc for the Suzuki–Miyaura reaction. From the results, key points were identified: both designed catalysts accelerated the reaction in EtOH and an open-flask setup, affording moderate to excellent yields within a short time (e.g., 30 min) even for deactivated aryl halides; the protocol can be applied to a great number of both cross-coupling partners, showing an excellent functional group tolerance; the catalysts can be recovered and reused without significant loss of activity. This protocol was used for the synthesis of a precursor of angiotensin II inhibitors such as valsartan, losartan, irbesartan, and telmisartan.

KCC-1 supported palladium nanoparticles as an efficient and sustainable nanocatalyst for carbonylative Suzuki–Miyaura cross-coupling

2016 ◽  
Vol 18 (21) ◽  
pp. 5890-5899 ◽  
Author(s):  
Prashant Gautam ◽  
Mahak Dhiman ◽  
Vivek Polshettiwar ◽  
Bhalchandra M. Bhanage
Keyword(s):  
Palladium Nanoparticles ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Cost Effective ◽  
Turnover Number ◽  
High Turnover ◽  
Cross Coupling Reaction ◽  
Supported Palladium ◽  
Very High

This work reports a cost-effective and sustainable protocol for the carbonylative Suzuki–Miyaura cross-coupling reaction catalyzed by palladium nanoparticles (Pd NPs) supported on fibrous nanosilica (KCC-1) with very high turnover number.

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