scholarly journals Research Progress and Challenges in the Treatment of Central Nervous System Metastasis of Non-Small Cell Lung Cancer

Cells ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2620
Author(s):  
Bin Wang ◽  
Hanfei Guo ◽  
Haiyang Xu ◽  
Hongquan Yu ◽  
Yong Chen ◽  
...  

Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors and has high morbidity and mortality rates. Central nervous system (CNS) metastasis is one of the most frequent complications in patients with NSCLC and seriously affects the quality of life (QOL) and overall survival (OS) of patients, with a median OS of untreated patients of only 1–3 months. There are various treatment methods for NSCLC CNS metastasis, including surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy, which do not meet the requirements of patients in terms of improving OS and QOL. There are still many problems in the treatment of NSCLC CNS metastasis that need to be solved urgently. This review summarizes the research progress in the treatment of NSCLC CNS metastasis to provide a reference for clinical practice.

2013 ◽  
Vol 8 (12) ◽  
pp. 1570-1573 ◽  
Author(s):  
Justin F. Gainor ◽  
Sai-Hong Ignatius Ou ◽  
Jennifer Logan ◽  
Lawrence F. Borges ◽  
Alice T. Shaw

2017 ◽  
Vol 12 (1) ◽  
pp. S939-S940
Author(s):  
Marcin Nicoś ◽  
Bożena Jarosz ◽  
Pawel Krawczyk ◽  
Kamila Wojas-Krawczyk ◽  
Aleksandra Bożyk ◽  
...  

2018 ◽  
Vol 18 (11) ◽  
pp. 1077-1083 ◽  
Author(s):  
Paweł Krawczyk ◽  
Renata Duchnowska ◽  
Marcin Nicoś ◽  
Dariusz Kowalski ◽  
Kamila Wojas-Krawczyk

2017 ◽  
Vol 28 (1) ◽  
pp. 77-86 ◽  
Author(s):  
Marcin Nicoś ◽  
Bożena Jarosz ◽  
Paweł Krawczyk ◽  
Kamila Wojas-Krawczyk ◽  
Tomasz Kucharczyk ◽  
...  

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