scholarly journals Nursing Genetic Research: New Insights Linking Breast Cancer Genetics and Bone Density

Healthcare ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 172
Author(s):  
Antonio Sanchez-Fernandez ◽  
Raúl Roncero-Martin ◽  
Jose M. Moran ◽  
Jesus Lavado-García ◽  
Luis Manuel Puerto-Parejo ◽  
...  
Keyword(s):  
Genetic Factors ◽  
Cancer Genetics ◽  
Genetic Research ◽  
Research Capacity ◽  
Interdisciplinary Cooperation ◽  
Bone Diseases ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone ◽  
Breast Cancer Genetics ◽  
The Relationship

Nursing research is expected to provide options for the primary prevention of disease and health promotion, regardless of pathology or disease. Nurses have the skills to develop and lead research that addresses the relationship between genetic factors and health. Increasing genetic knowledge and research capacity through interdisciplinary cooperation as well as the development of research resources, will accelerate the rate at which nurses contribute to the knowledge about genetics and health. There are currently different fields in which knowledge can be expanded by research developed from the nursing field. Here, we present an emerging field of research in which it is hypothesized that genetics may affect bone metabolism. Better insight of genetic factors that are contributing to metabolic bone diseases would allow for focused nursing care and preventive interventions.

The relationship between metabolic bone diseases and fingernail calcium levels in the elderly

2012 ◽  
Vol 3 (6) ◽  
pp. 341-344 ◽  
Author(s):  
Y. Yesil ◽  
M.E. Kuyumcu ◽  
Z.A. Ozturk ◽  
Z. Ulger ◽  
U. Sahin ◽  
...  
Keyword(s):  
The Elderly ◽  
Bone Diseases ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone ◽  
The Relationship

scholarly journals Osteonecrosis of the Jaw associated with the Use of Bisphosphonates

2015 ◽  
Vol 6 (2) ◽  
pp. 116-122 ◽  
Author(s):  
Matheus Coelho Bandéca ◽  
Rafael Soares Diniz ◽  
Francisco José Lima Maciel ◽  
Andrezza De Almeida Bastos Maciel ◽  
Marcio Antônio Rodrigues Araújo ◽  
...  
Keyword(s):  
Osteonecrosis Of The Jaw ◽  
Complete Healing ◽  
Bone Diseases ◽  
Necrotic Bone ◽  
Maxillofacial Region ◽  
Dental Surgery ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone ◽  
History Of ◽  
The Relationship

ABSTRACT The bisphosphonates (BPs) are drugs used to treat metabolic bone diseases involving intense bone resorption. These compounds are capable of altering the bone remodeling by decreasing osteoclast activity. However, the changes that these drugs cause to the bones of patients without a history of cervico-facial radiotherapy can result in a complication called osteonecrosis of the jaw, which is caused by dental surgery, trauma or infections. Osteonecrosis of the jaw is characterized by an exposed necrotic bone in the maxillofacial region, persisting for prolonged periods without complete healing. Based on clinical experience and literature review, the aim of the present study was to describe a clinical case of a patient with osteoporosis taking alendronate (Fosamax®) to control the progression of the disease with a characteristic clinical condition of osteonecrosis of the jaw. We evaluated the etiological factors, the relationship between BPs and osteonecrosis of the jaw, the mechanisms of action and possible treatments. How to cite this article Diniz RS, Maciel FJL, De Almeida Bastos Maciel A, Araújo MAR, Lamha APF, Bandeca MC, Pereira EM. Osteonecrosis of the Jaw associated with the Use of Bisphosphonates. World J Dent 2015;6(2):116-122.

Is oral health correlated with skeletal phenotype in primary metabolic bone diseases? A preliminary report of the Greek experience

2019 ◽  
Author(s):  
Artemis Doulgeraki ◽  
Margarita Gatzogianni ◽  
Andreas Agouropoulos ◽  
Helen Athanasopoulou ◽  
Georgios Polyzois ◽  
...  
Keyword(s):  
Oral Health ◽  
Preliminary Report ◽  
Bone Diseases ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone ◽  
Skeletal Phenotype

scholarly journals Genetic approaches to metabolic bone diseases

2018 ◽  
Vol 85 (6) ◽  
pp. 1147-1160 ◽  
Author(s):  
Fadil M. Hannan ◽  
Paul J. Newey ◽  
Michael P. Whyte ◽  
Rajesh V. Thakker
Keyword(s):  
Bone Diseases ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone

scholarly journals Bone biopsy in nephrology practice

2018 ◽  
Vol 40 (4) ◽  
pp. 366-374 ◽  
Author(s):  
Fellype de Carvalho Barreto ◽  
Cleber Rafael Vieira da Costa ◽  
Luciene Machado dos Reis ◽  
Melani Ribeiro Custódio
Keyword(s):  
Bone Biopsy ◽  
Bone Lesion ◽  
Bone Diseases ◽  
Serum Biomarkers ◽  
Medical Residency ◽  
Dynamic Information ◽  
Gold Standard Method ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone ◽  
The World

Abstract Renal osteodystrophy (ROD), a group of metabolic bone diseases secondary to chronic kidney disease (CKD), still represents a great challenge to nephrologists. Its management is tailored by the type of bone lesion - of high or low turnover - that cannot be accurately predicted by serum biomarkers of bone remodeling available in daily clinical practice, mainly parathyroid hormone (PTH) and alkaline phosphatase (AP). In view of this limitation, bone biopsy followed by bone quantitative histomorphometry, the gold-standard method for the diagnosis of ROD, is still considered of paramount importance. Bone biopsy has also been recommended for evaluation of osteoporosis in the CKD setting to help physicians choose the best anti-osteoporotic drug. Importantly, bone biopsy is the sole diagnostic method capable of providing dynamic information on bone metabolism. Trabecular and cortical bones may be analyzed separately by evaluating their structural and dynamic parameters, thickness and porosity, respectively. Deposition of metals, such as aluminum and iron, on bone may also be detected. Despite of these unique characteristics, the interest on bone biopsy has declined over the last years and there are currently few centers around the world specialized on bone histomorphometry. In this review, we will discuss the bone biopsy technique, its indications, and the main information it can provide. The interest on bone biopsy should be renewed and nephrologists should be capacitated to perform it as part of their training during medical residency.

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