Investigation of the Impact of Endodontic Therapy on Survival among Dialysis Patients in Taiwan: A Nationwide Population-Based Cohort Study

Objectives Dental problems occur widely in patients with chronic kidney disease (CKD) and may increase comorbidities. Root canal therapy (RCT) is a common procedure for advanced decayed caries with pulp inflammation and root canals. However, end-stage renal disease (ESRD) patients are considered to have a higher risk of potentially life-threatening infections after treatment and might fail to receive satisfactory dental care such as RCT. We investigated whether appropriate intervention for dental problems had a potential impact among dialysis patients. Design Men and women who began maintenance dialysis (hemodialysis or peritoneal dialysis) between January 1, 2000, and December 31, 2015, in Taiwan (total 12,454 patients) were enrolled in this study. Participants were followed up from the first reported dialysis date to the date of death or end of dialysis by December 31, 2015. Setting Data collection was conducted in Taiwan. Results A total of 2633 and 9821 patients were classified into the RCT and non-RCT groups, respectively. From the data of Taiwan’s National Health Insurance, a total of 5,092,734 teeth received RCT from 2000 to 2015. Then, a total of 12,454 patients were followed within the 16 years, and 4030 patients passed away. The results showed that members of the non-RCT group (34.93%) had a higher mortality rate than those of the RCT group (22.79%; p = 0.001). The multivariate-adjusted hazard ratio for the risk of death was 0.69 (RCT vs. non-RCT; p = 0.001). Conclusions This study suggested that patients who had received RCT had a relatively lower risk of death among dialysis patients. Infectious diseases had a significant role in mortality among dialysis patients with non-RCT. Appropriate interventions for dental problems may increase survival among dialysis patients. Abbreviations: CKD = chronic kidney disease, ESRD = end-stage renal disease, RCT = root canal therapy.

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Competing risk of death and end-stage renal disease in incident chronic kidney disease (stages 3 to 5): the EPIRAN community-based study

BMC Nephrology ◽

10.1186/s12882-016-0379-3 ◽

2016 ◽

Vol 17 (1) ◽

Cited By ~ 4

Author(s):

Carole Ayav ◽

Jean-Baptiste Beuscart ◽

Serge Briançon ◽

Alain Duhamel ◽

Luc Frimat ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Renal Disease ◽

End Stage Renal Disease ◽

Community Based ◽

Risk Of Death ◽

Incident Chronic Kidney Disease ◽

Stage Renal Disease ◽

End Stage ◽

Disease Stages

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Nutrition in Kidney Failure

10.2310/nephro.12064 ◽

2020 ◽

Author(s):

Serpil Muge Deger ◽

T. Alp Ikizler

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Renal Disease ◽

End Stage Renal Disease ◽

Maintenance Hemodialysis ◽

Protein Energy Wasting ◽

Risk Of Death ◽

Protein Energy ◽

Stage Renal Disease ◽

End Stage

Among the many factors that affect outcome in patients with chronic kidney disease (CKD), a state of metabolic and nutritional derangements, more aptly called protein-energy wasting (PEW) CKD, plays a major role.1 Multiple studies now indicate that PEW is highly prevalent and is closely associated with important clinical outcomes, such as hospitalizations and risk of death in this patient population. The focus of this review is to provide an overview of nutrition and metabolism in all stages of CKD, including end-stage renal disease (ESRD). This review contains 3 figures, 5 tables, and 105 references. Key words: chronic-kidney disease (CKD), dialysis, end stage renal disease (ESRD), inflammation, maintenance hemodialysis (MHD), protein-energy wasting (PEW),uremia

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Preoperative Evaluation in Patients With End-Stage Renal Disease and Chronic Kidney Disease

Health Services Insights ◽

10.1177/1178632917713020 ◽

2017 ◽

Vol 10 ◽

pp. 117863291771302 ◽

Cited By ~ 2

Author(s):

Rabih Nasr ◽

Sridhar Chilimuri

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Renal Disease ◽

End Stage Renal Disease ◽

Preoperative Evaluation ◽

Dialysis Session ◽

Dialysis Access ◽

Dialysis Patients ◽

Stage Renal Disease ◽

End Stage

Optimal preoperative management of dialysis patients remains challenging. Patients with end-stage renal disease (ESRD) have higher mortality in the perioperative setting compared with non-ESRD patients. However, it is well established that dialysis should be done on the day before surgery. Additional dialysis session prior to surgery does not improve outcomes. All dialysis patients should undergo blood work to check electrolytes and especially serum potassium prior to any surgery. Some medications, including angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and diuretics, should be stopped prior to surgery to minimize hemodynamic changes during surgery. The dialysis access should be carefully examined for any signs of infection. The arteriovenous fistula or graft should be evaluated for patency. Glycemic control in diabetic ESRD and chronic kidney disease patients is very important, and clinicians should be aware of the risk of bleeding and the appropriate analgesics that can be used in dialysis patients in the perioperative setting. In conclusion, preoperative evaluation in patients with ESRD should be a multidisciplinary approach.

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Prevalence of end stage renal disease in diabetic obese and hypertensive patients and cardiovascular risk in dialysis patients

Pakistan Journal of Pharmaceutical Research ◽

10.22200/pjpr.2016142-48 ◽

2016 ◽

Vol 2 (1) ◽

pp. 42 ◽

Cited By ~ 2

Author(s):

Muhammad Hanif ◽

Hina Javed ◽

Umair Jallani ◽

Nazar Muhammad Ranjha

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Renal Disease ◽

End Stage Renal Disease ◽

Kidney Stone ◽

Cardiovascular Risks ◽

Dialysis Patients ◽

Hypertensive Patients ◽

Stage Renal Disease ◽

End Stage

Chronic kidney disease(CKD) is the cause of irreversible detoriation of renal function which leads to end stage renal disease(ESRD).incidence of end stage renal disease has increased dramatically during last 30 years and screening for early stages of chronic kidney disease is often suggested as preventive measure.the main cause of end stage renal disease are diabetes, high blood pressure,hyperlipidemia and obesity.obesity and increased BMI are the cause of kidney stone and chronic kidney disease.this reports aim to determine the prevalance of end stage renal disease in diabetic obese individuals and other problems that are more likely to be encountered in the end stage renal disease are cardiovascular risks in dialysis patients.GFR and creatinine clearance are used as the major diagnostic tool to determined the kidney function. calcium level is also used as predictive factor to determine the vascular calcification.

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