scholarly journals High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms

2021 ◽  
Vol 10 (2) ◽  
pp. 225
Author(s):  
Łukasz Zwarzany ◽  
Ernest Tyburski ◽  
Wojciech Poncyljusz
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Vessel Wall ◽  
Intracranial Aneurysms ◽  
Aneurysm Rupture ◽  
Resonance Imaging ◽  
Aneurysm Wall ◽  
Conventional Risk Factors

Background: We decided to investigate whether aneurysm wall enhancement (AWE) on high-resolution vessel wall magnetic resonance imaging (HR VW-MRI) coexists with the conventional risk factors for aneurysm rupture. Methods: We performed HR VW-MRI in 46 patients with 64 unruptured small intracranial aneurysms. Patient demographics and clinical characteristics were recorded. The PHASES score was calculated for each aneurysm. Results: Of the 64 aneurysms, 15 (23.4%) showed wall enhancement on post-contrast HR VW-MRI. Aneurysms with wall enhancement had significantly larger size (p = 0.001), higher dome-to-neck ratio (p = 0.024), and a more irregular shape (p = 0.003) than aneurysms without wall enhancement. The proportion of aneurysms with wall enhancement was significantly higher in older patients (p = 0.011), and those with a history of prior aneurysmal SAH. The mean PHASES score was significantly higher in aneurysms with wall enhancement (p < 0.000). The multivariate logistic regression analysis revealed that aneurysm irregularity and the PHASES score are independently associated with the presence of AWE. Conclusions: Aneurysm wall enhancement on HR VW-MRI coexists with the conventional risk factors for aneurysm rupture.

scholarly journals Vessel wall magnetic resonance imaging in intracranial aneurysms: Principles and emerging clinical applications

2019 ◽  
Vol 26 (2) ◽  
pp. 135-146 ◽  
Author(s):  
Corrado Santarosa ◽  
Branden Cord ◽  
Andrew Koo ◽  
Pervinder Bhogal ◽  
Ajay Malhotra ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Vessel Wall ◽  
Intracranial Aneurysms ◽  
High Volume ◽  
Resonance Imaging ◽  
Aneurysm Wall ◽  
Unruptured Intracranial Aneurysms ◽  
Technical Principles

Intracranial high-resolution vessel wall magnetic resonance imaging is an imaging paradigm that complements conventional imaging modalities used in the evaluation of neurovascular pathology. This review focuses on the emerging utility of vessel wall magnetic resonance imaging in the characterization of intracranial aneurysms. We first discuss the technical principles of vessel wall magnetic resonance imaging highlighting methods to determine aneurysm wall enhancement and how to avoid common interpretive pitfalls. We then review its clinical application in the characterization of ruptured and unruptured intracranial aneurysms, in particular, the emergence of aneurysm wall enhancement as a biomarker of aneurysm instability. We offer our perspective from a high-volume neurovascular center where vessel wall magnetic resonance imaging is in routine clinical use.

Abstract 199: A Predicting Model of Aneurysm Rupture Status Based on High-resolution Magnetic Resonance Imaging

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Feng Liang ◽  
Fanying Li ◽  
Siqi Ou ◽  
Yibing Yang ◽  
Tiewei Qi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Logistic Regression ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Aneurysm Rupture ◽  
Resonance Imaging ◽  
Multivariate Logistic Regression ◽  
Predicting Model ◽  
Ruptured Aneurysms ◽  
Aneurysm Wall

Objective: Aneurysm wall enhancement on high-resolution magnetic resonance imaging (HR-MRI) is seen in ruptured aneurysms. However, site, size and other morphology features also contribute to aneurysm rupture. We introduce a model combining aneurysm wall enhancement and these factors to predict rupture status of aneurysm. Methods: We prospectively collected data of patients with intracranial aneurysms who received HR-MRI scan before surgical treatment. Aneurysms were divided into ruptured group (n=25) and unruptured group (n=116). Clinical features, imaging features including size, site, width of neck, aspect ratio(AR), daughter sac, and aneurysm wall enhancement scale(AWES) in both groups were analyzed. AWES was categorized on HR-MRI contrast-enhanced T1WI images: grade 0, no enhancement; grade 1, enhancement greater than grade 0 but less than that of the pituitary infundibulum or choroidal plexus; grade 2, enhancement greater than or equal to that of the pituitary infundibulum or choroidal plexus. Univariate and multivariate logistic regression were performed to evaluate the risk factors of aneurysm rupture status. Results: AWES(P<0.001),AR(P=0.0001),daughter sac(P=0.001) and non-ICA location(P=0.002) were higher in ruptured aneurysms. Multivariate logistic regression showed that AWES(OR 5.99,95%CI 2.51-14.29,P<0.001),daughter sac(OR6.22,95%CI 1.68-23.16,P=0.006),and non-ICA location(OR6.25,95%CI 1.35-28.30,P=0.019) were associated with aneurysm rupture status. A simplified predicting model (SAD model) using site(non-ICA,1; ICA,0), AWES(2,1,0), daughter sac(yes,1; no,0) predicted 0, 2%, 12%, 44% and 100% of ruptured aneurysms from scale 0 to 4(Area under curve 0.8920, 95%CI 0.8241-0.9404). Conclusion: SAD model is helpful to predict rupture stutus of aneurysm and may provide a new tool to screen high-risk aneurysms.

High resolution vessel wall magnetic resonance imaging in HIV associated vasculopathy

2017 ◽  
Vol 381 ◽  
pp. 421-422
Author(s):  
G. Taricani Kubota ◽  
R. de Faria Ferreira ◽  
T. Rocha Figueiredo ◽  
G. Titoneli dos Santos ◽  
L. Martins Tavares Scianni Morais ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Vessel Wall ◽  
Resonance Imaging

Abstract WMP71: Moyamoya-atherosclerosis Syndrome: Clinical and High-resolution Magnetic Resonance Imaging Features

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Lian Duan ◽  
Wei-Hai Xu ◽  
Cong Han
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Moyamoya Disease ◽  
Treatment Strategies ◽  
Diagnostic Process ◽  
Imaging Features ◽  
Intracranial Atherosclerosis ◽  
Resonance Imaging

Introduction: The diagnosis in the patients with angiographic moyamoya findings and atherogenic risk factors is challenging. In this study, we try to incorporate high-resolution magnetic resonance imaging (HRMRI) into the diagnostic process of intracranial atherosclerosis associated moyamoya syndrome. Methods: From March 2013 to March 2014, HRMRI was consecutively performed on adult patients with angiographic moyamoya. The patients were classified as moyamoya - plaques (MMD-P) if a plaque could be identified or as moyamoya - no plaques (MMD-NP) if a plaque could not be identified. The angiography, HRMRI findings and atherogenic risk factors of these patients were analyzed. Results: Fifty-one patients (mean age 39±9, 20 males) were enrolled. On traditional angiography, probable intracranial atherosclerosis was identified in 5 patients, no definite diagnosis in 12 patients, and moyamoya disease in 34 patients. On HRMRI, 15 out of 32 patients with risk factors and 4 out of 19 patients without risk factors were found to have plaques and were diagnosed as MMD-P, while the other 32 patients were diagnosed as MMD-NP. The MMD-P patients were more likely to be older and male and were less likely to have cerebral hemorrhage and a history of disease progression. Conclusions: Our study suggests that HRMRI can help diagnose intracranial atherosclerosis more accurately in moyamoya disease patients with atherogenic risk factors. The distinct clinical features between MMD-P and MMD-NP patients suggest different underlying pathophysiology and therefore potentially different treatment strategies.

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