A Prospective Multicenter Study of “Inside Stents” for Biliary Stricture: Multicenter Evolving Inside Stent Registry (MEISteR)

Background: Endoscopic biliary stent placement is the standard of care for biliary strictures, but stents across the papilla are prone to duodenobiliary reflux, which can cause stent occlusion. Preliminary studies of “inside stents” placed above the papilla showed encouraging outcomes, but prospective data with a large cohort were not reported. Methods: This was a prospective multicenter registry of commercially available inside stents for benign and malignant biliary strictures. Primary endpoint was recurrent biliary obstruction (RBO). Secondary endpoints were technical success of stent placement and removal, adverse events, and stricture resolution. Results: A total of 209 inside stents were placed in 132 (51 benign and 81 malignant) cases with biliary strictures in 10 Japanese centers. During the follow-up period of 8.4 months, RBO was observed in 19% of benign strictures. The RBO rate was 49% in malignant strictures, with the median time to RBO of 4.7 months. Technical success rates of stent placement and removal were both 100%. The adverse event rate was 8%. Conclusion: This prospective multicenter study demonstrated that inside stents above the papilla were feasible in malignant and benign biliary strictures, but a randomized controlled trial is warranted to confirm its superiority to conventional stents across the papilla.

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49 Temporary Placement of Fully Covered Self-Expandable Metallic Stents for Benign Biliary Strictures. Preliminary Results – A Prospective Multicenter Study

Gastroenterology ◽

10.1016/s0016-5085(10)60044-3 ◽

2010 ◽

Vol 138 (5) ◽

pp. S-10

Author(s):

Ulriikka Chaput ◽

Marianne Gaudric ◽

Philippe Bichard ◽

Paul Bauret ◽

Dimitri Coumaros ◽

...

Keyword(s):

Multicenter Study ◽

Metallic Stents ◽

Biliary Strictures ◽

Prospective Multicenter Study ◽

Preliminary Results ◽

Benign Biliary Strictures ◽

Expandable Metallic Stents

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Percutaneous Transhepatic Biodegradable Biliary Stent Placement for Benign Biliary Strictures

Digestive Disease Interventions ◽

10.1055/s-0041-1733796 ◽

2021 ◽

Author(s):

Shaima Abulqasim ◽

Mohammad Arabi ◽

Khalid Almasar ◽

Bayan AlBdah ◽

Refaat Salman

Keyword(s):

Stent Placement ◽

Major Complication ◽

Biliary Strictures ◽

Effective Treatment Option ◽

Duct Occlusion ◽

Benign Biliary Strictures ◽

Biodegradable Stents ◽

Bile Duct Occlusion ◽

Stricture Recurrence

AbstractThis article aimed to assess the safety and effectiveness of biodegradable stents in the management of benign biliary strictures. This is a retrospective observational study that included all adult patients who had biodegradable stent placement for a benign cause of biliary stricture between July 2016 and August 2019. Nineteen patients were included. Seventeen patients had liver transplant. One patient had hepaticojejunostomy due to primary sclerosing cholangitis and one patient had iatrogenic left main bile duct occlusion. Stents were successfully deployed in all 19 patients (technical success: 100%). Patency rate was 90% (17/19) at 6 months and 80% (12/15) at 12 months. Seven patients in the study had stricture recurrence and needed reintervention with mean time to reintervention of 418 days (range: 8–1,155 days). There was one major complication due to cholangitis and sepsis, which required a treatment course with piperacillin/tazobactam for 10 days. No procedure-related pancreatitis or deaths occurred. Biodegradable stents are a safe and effective treatment option for benign biliary strictures and can achieve long-term patency without the need for reinterventions.

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Efficacy of prophylactic pancreatic stent placement after endoscopic snare major papillectomy - A prospective, multicenter study

Pancreatology ◽

10.1016/j.pan.2019.05.187 ◽

2019 ◽

Vol 19 ◽

pp. S72

Author(s):

Sang-Woo Cha ◽

Kyo-Sang Yoo ◽

Tae Hoon Lee ◽

Young Deok Cho ◽

Sang-Heum Park ◽

...

Keyword(s):

Multicenter Study ◽

Stent Placement ◽

Pancreatic Stent ◽

Prospective Multicenter Study

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Temporary placement of partially covered self-expandable metal stents for anastomotic biliary strictures after liver transplantation: a prospective, multicenter study

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2010.08.016 ◽

2010 ◽

Vol 72 (6) ◽

pp. 1167-1174 ◽

Cited By ~ 71

Author(s):

Ulriikka Chaput ◽

Olivier Scatton ◽

Philippe Bichard ◽

Thierry Ponchon ◽

Ariane Chryssostalis ◽

...

Keyword(s):

Liver Transplantation ◽

Multicenter Study ◽

Metal Stents ◽

Biliary Strictures ◽

Prospective Multicenter Study

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Balloon enteroscopy-assisted radial incision and cutting method for refractory hepaticojejunostomy anastomotic strictures

Endoscopy ◽

10.1055/a-0838-5557 ◽

2019 ◽

Vol 51 (06) ◽

pp. 566-570

Author(s):

Tadahisa Inoue ◽

Mayu Ibusuki ◽

Rena Kitano ◽

Yuji Kobayashi ◽

Tomohiko Ohashi ◽

...

Keyword(s):

Stent Placement ◽

Clinical Success ◽

Balloon Dilation ◽

Adverse Event Rate ◽

Treatment Technique ◽

Technical Success ◽

Balloon Enteroscopy ◽

Technical Success Rate ◽

Radial Incision ◽

Anastomotic Strictures

Abstract Background Balloon enteroscopy-assisted balloon dilation and temporary biliary stent placement are effective for hepaticojejunostomy anastomotic strictures (HJAS), but the re-stenosis rates are relatively high. We examined the feasibility and efficacy of a novel treatment technique for refractory HJAS, called balloon enteroscopy-assisted radial incision and cutting (BE-RIC). Methods Between January 2016 and June 2018, 11 patients with refractory HJAS that recurred after balloon dilation and/or stent placement, underwent BE-RIC. We evaluated the technical success, clinical success, adverse events, and re-stenosis rates associated with BE-RIC. Results The technical success rate of BE-RIC was 91 % (10/11). Clinical success was achieved in all patients who underwent technically successful procedures. The procedure-related adverse event rate was 9 % (1/11). No re-stenosis was observed during the follow-up period; 9 patients were followed up for more than 6 months, and of these, 5, 4, and 2 patients were followed up for more than 12, 18, and 24 months, respectively, without re-stenosis. Conclusions BE-RIC for refractory HJAS showed favorable results. BE-RIC might be a useful option for treating refractory HJAS.

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