scholarly journals Changes in Eyelid Pressure and Dry Eye Status after Orbital Decompression in Thyroid Eye Disease

2021 ◽  
Vol 10 (16) ◽  
pp. 3687
Author(s):  
Yasuhiro Takahashi ◽  
Aric Vaidya ◽  
Hirohiko Kakizaki
Keyword(s):  
Dry Eye ◽  
Elevated Pressure ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Maximum Pressure ◽  
Orbital Decompression ◽  
Pressure Group ◽  
Plateau Phase ◽  
Upper Eyelid ◽  
Group 1

The aim of this prospective observational study was to examine changes in eyelid pressure and dry eye status after orbital decompression in thyroid eye disease (TED). In 16 patients (29 sides), upper eyelid pressure at plateau phase and maximum pressure were measured. TED status was evaluated through the Hertel exophthalmometric value and margin reflex distance (MRD)-1 and 2. Dry eye status was quantified through corneal fluorescein staining, tear break-up time, Schirmer test I results, meibomian gland dysfunction (MGD), tear meniscus height, and superior limbic keratoconjunctivitis (SLK). Patients were classified into two groups: patients with decreased eyelid pressure (Group 1) and those with elevated pressure (Group 2). Consequently, neither the maximum upper eyelid pressure nor pressure at plateau phase significantly changed after surgery (p > 0.050). Some parameters about MGD improved after surgery, but the other parameters on dry eye, MGD, and SLK worsened or did not change. MRD-1 decreased more (p = 0.028), and the ratio of patients in whom SLK improved after surgery was larger in Group 1 (p = 0.030). These results indicate that upper eyelid pressure tends to decrease postoperatively in patients with a high upper eyelid position, resulting in improvement of SLK.

scholarly journals Correlation between uniocular deviation and duction changes following different decompression surgeries in thyroid eye disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jie Guo ◽  
Xiaofeng Li ◽  
Ruiqi Ma ◽  
Jiang Qian
Keyword(s):  
Computed Tomography ◽  
Lateral Wall ◽  
Contractile Force ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Decompression Surgery ◽  
Inferior Wall ◽  
Orbital Decompression ◽  
Significant Difference ◽  
Ocular Deviation

Abstract Background Postoperative ocular imbalance is an important problem for orbital decompression surgery in thyroid eye disease (TED). The aim of this study was to evaluate the changes in unilateral ocular deviation and duction following orbital decompression and discuss the biomechanics of ocular imbalance. Methods Fifty-four TED patients who underwent unilateral orbital decompression were included. Fifteen patients underwent 1-wall (deep lateral wall) decompression, 18 patients underwent 2-wall (deep lateral and medial wall) decompression and 21 patients underwent 3-wall (deep lateral, medial and inferior wall) decompression. Objective and subjective deviation of the operated eyes were evaluated using the prism test and synoptophore, respectively. Ocular ductions were measured using Hirschberg’s method. The diameters of the extraocular rectus were measured by computed tomography. Results Ocular deviation and duction showed no significant difference after 1-wall decompression (p = 0.25–0.89). Esotropia increased after 2-wall decompression (p = 0.001–0.02), and hypotropia increased after 3-wall decompression (p = 0.02). Adduction increased but abduction decreased following 2-wall and 3-wall decompression (p < 0.05). Infraduction increased following 3-wall decompression (p < 0.001). Additionally, the increase in esotropia was significantly correlated with the increase in adduction and with the decrease in abduction (r = 0.37–0.63, p < 0.05). There were significant correlations between the diameter of the medial rectus and the increase in esotropia, the increase in adduction and the decrease in abduction postoperatively (r = 0.35–0.48, p < 0.05). Conclusions The changes in ocular deviation and duction were different after 1-wall, 2-wall and 3-wall orbital decompression. The increased contractile force of the rectus may be an important reason for strabismus changes after orbital decompression surgery.

scholarly journals Patients’ expectations for the functional and psychosocial outcomes of orbital decompression surgery for thyroid eye disease: a qualitative study

2017 ◽  
Vol 23 (4) ◽  
pp. 475-484
Author(s):  
Sadie Wickwar ◽  
Hayley McBain ◽  
Matthew R. Edmunds ◽  
Daniel G. Ezra ◽  
Geoffrey E. Rose ◽  
...  
Keyword(s):  
Qualitative Study ◽  
Psychosocial Outcomes ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Decompression Surgery ◽  
Orbital Decompression

scholarly journals Correlation Between Uniocular Deviation and Duction Changes Following Different Decompression Surgeries in Thyroid Eye Disease

2020 ◽  
Author(s):  
Jie Guo ◽  
Xiaofeng Li ◽  
Ruiqi Ma ◽  
Jiang Qian
Keyword(s):  
Lateral Wall ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Decompression Surgery ◽  
Inferior Wall ◽  
Orbital Decompression ◽  
Orbital Cavity ◽  
Significant Difference ◽  
Ocular Deviation ◽  
Fellow Eyes

Abstract Background: Postoperative ocular imbalance is an important problem for orbital decompression surgery in thyroid eye disease (TED). To evaluate the changes of unilateral ocular deviation and duction following orbital decompression and discuss the possible biomechanics of ocular imbalance.Methods: Fifty-four TED patients who underwent unilateral orbital decompression were included. 15 patients underwent 1-wall (deep lateral wall) decompression, 18 patients underwent 2-wall (deep lateral and medial wall) decompression and 21 patients underwent 3-wall (deep lateral, medial and inferior wall) decompression. Objective and subjective deviation of the operated eyes compared with the fellow eyes were evaluated using prism test and synoptophore, respectively. Ocular ductions were measured using Hirschberg’s method. The diameters of extraocular rectus were measured by computed tomography.Results: Ocular deviation and duction showed no significant difference after 1-wall decompression (p=0.25~0.89). Esotropia increased after 2-wall decompression (p=0.001~0.02). Hypotropia increased after 3-wall decompression (p=0.02). Adduction increased but abduction decreased following 2-wall and 3-wall decompression (p<0.05). Infraduction increased following 3-wall decompression (p<0.001). Additionally, the increase of esotropia had significant correlations with the increase of adduction and with the decrease of abduction (r=0.37~0.63, p<0.05). There were significant correlations between the diameter of medial rectus and the increase of esotropia, the increase of adduction and the decrease of abduction postoperatively (r=0.35~0.48, p<0.05).Conclusions: The changes in ocular deviation and duction were different after 1-wall, 2-wall and 3-wall orbital decompression. The expansion of orbital cavity and the increased contractile force of rectus might be important reasons for strabismus changes following decompression surgery.

Subjective versus objective dry eye disease in patients with moderate-severe thyroid eye disease

2018 ◽  
Vol 16 (4) ◽  
pp. 458-462 ◽  
Author(s):  
Mohsen Bahmani Kashkouli ◽  
Sayyed Amirpooya Alemzadeh ◽  
Hossein Aghaei ◽  
Farzad Pakdel ◽  
Parya Abdolalizadeh ◽  
...  
Keyword(s):  
Dry Eye ◽  
Dry Eye Disease ◽  
Thyroid Eye Disease ◽  
Eye Disease

Spontaneous orbital decompression in thyroid eye disease: new measurement methods and its influential factors

2020 ◽  
Vol 258 (10) ◽  
pp. 2321-2329
Author(s):  
Aric Vaidya ◽  
Patricia Ann L. Lee ◽  
Yoshiyuki Kitaguchi ◽  
Hirohiko Kakizaki ◽  
Yasuhiro Takahashi
Keyword(s):  
Measurement Methods ◽  
Influential Factors ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Orbital Decompression

ORBITAL DECOMPRESSION FOR OPTIC NEUROPATHY SECONDARY TO THYROID EYE DISEASE

1988 ◽  
Vol 98 (7) ◽  
pp. 712???716 ◽  
Author(s):  
STEVEN D. SCHAEFER ◽  
JAMES H. MERRITT ◽  
LANNY G. CLOSE
Keyword(s):  
Optic Neuropathy ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Orbital Decompression

Course of upper eyelid retraction in thyroid eye disease

2019 ◽  
Vol 104 (2) ◽  
pp. 254-259
Author(s):  
Dong Cheol Lee ◽  
Stephanie M Young ◽  
Yoon-Duck Kim ◽  
Kyung In Woo
Keyword(s):  
Positive Family History ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Eye Disease ◽  
Eye Disease ◽  
Clinical Activity ◽  
Eyelid Retraction ◽  
Tertiary Institution ◽  
Upper Eyelid ◽  
Upper Eyelid Retraction ◽  
History Of

AimsTo evaluate the natural course of upper eyelid retraction (UER) in patients with thyroid eye disease (TED) and factors affecting its course.MethodsRetrospective non-interventional cohort study in a single tertiary institution from March 2006 to March 2015 on patients with TED with (1) unilateral or bilateral UER within 6 months from initial presentation, and (2) no prior interventions nor surgical treatment for their UER. Main outcomes and measures were mean margin reflex distance 1 (MRD1) and factors associated with UER improvement.ResultsThere were a total of 61 patients and 81 eyes (41 unilateral and 20 bilateral UER). Mean age was 42.3±15.1 years. Mean MRD1 decreased from 6.1 mm at presentation to 4.8 mm at 12 months, and 4.4 mm at 24 months. The proportion of eyes with normalisation of lid height increased from 0% at presentation to 22.2% at 6 months, 37.0% at 12 months and 49.4% at 24 months. Mean time to normalisation of MRD1 was 18.0±12.4 months. A positive family history of TED was found to be associated with a 6.2 times lower likelihood of normalisation. Change in exophthalmometry, clinical activity score and thyroid-stimulating immunoglobulin were significantly correlated to change in MRD1 (p<0.05). There was no correlation between change in MRD1 and thyroid-stimulating hormone receptor antibodies.ConclusionAn improved knowledge of the natural history of UER in TED will allow us to better decide and evaluate the optimal management for such patients.

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