scholarly journals Course of Metal Ions after a Revision of Malfunctioning Metal-on-Metal Total Hip Prostheses

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 115
Author(s):  
Annamaria Nicolli ◽  
Isabella Bortoletti ◽  
Stefano Maso ◽  
Andrea Trevisan

The present research evaluated the course of cobalt and chromium in the blood and urine after the revision of metal-on-metal with a ceramic-on-polyethylene total hip arthroplasty. Seven patients were enrolled for hip prosthesis revision owing to ascertained damage of the implant. Metals in the blood and urine were evaluated before and after the hip revision. The double measurement before the total hip revision revealed high levels of metal ions (on average, 88.1 µg/L of cobalt in the blood, 399.0 µg/g of creatinine cobalt in the urine, 46.8 µg/L of chromium in the blood, and 129.6 µg/g of creatinine chromium in the urine at the first measurements), with an increasing trend between the first and second dosage. Within a week after the hip revision, the levels of metal ions significantly decreased by approximately half. Four to six months after the operation, the cobalt levels were found near to the reference values, whereas the chromium levels reached 25% of the values measured before the revision. The revision of malfunctioning metal-on-metal implants produced a dramatic decrease of metal ions in biological fluids, although it did not completely rescue the chromium level.

2013 ◽  
Vol 741 ◽  
pp. 67-72 ◽  
Author(s):  
Gheorghe I. Gheorghe ◽  
Liliana Laura Badita

Total hip prosthesis (THP) is the most success of the 20th century in orthopaedic biomedical engineering. However due to difficult conditions within the human body its durability is generally limited to 15-16 years. THP is a bio-tribosystem, on which many mechanical, thermal, chemical and biological factors act. This paper presents the results of an analysis regarding the topography and tribological parameters of femoral heads structures before and after TiN coating. We report on the synthesis of TiN thin films on steel substrates by pulsed laser deposition (PLD) method for improving the mechanical characteristics of the structures. Adhesion resistance of the coating on the sub-layer was evaluated by scratching tests accompanied by Optical Microscopy (OM), Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM). As a principal result, this work points out that TiN protective coatings deposited by PLD technique with the maximum number of pulses can represent an alternative technology to ensure adhesion and scratch resistance of TiN coatings on femoral heads.


2014 ◽  
Vol 85 (4) ◽  
pp. 355-362 ◽  
Author(s):  
Mette Holm Hjorth ◽  
Kjeld Søballe ◽  
Stig Storgaard Jakobsen ◽  
Nina Dyrberg Lorenzen ◽  
Inger Mechlenburg ◽  
...  

2015 ◽  
Vol 26 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Maarten C. Koper ◽  
Nina M.C. Mathijssen ◽  
Stephan B.W. Vehmeijer

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_1) ◽  
Author(s):  
Shiva P Ponamgi ◽  
Sunita Sharma ◽  
Christopher V DeSimone ◽  
Cody Wyles ◽  
Philip Philip Sun ◽  
...  

Introduction: One million patients around the world have had total hip arthorplasty with 35% of them having metal-on-metal implants. Although there have been some case reports of cobalt cardiotoxicity from arthroprosthetic cobaltism resulting in dilated cardiomyopathy, incidence of cardiomyopathy and mortality in these patients is unknown. Objective: We therefore sought to determine the incidence of new onset cardiomyopathy (EF <40%) and associated mortality, in patients with metal hip arthroplasty. Methods: We retrospectively examined the records of the patients form our institutional total hip arthroplasty registry (Metal on Metal: MoM, Metal on Polyethylene: MoP, Ceramic on Ceramic: CoC and Ceramic on Polyethylne: CoP). Among 122 patients with baseline and follow up echocardiograms, cobalt and chromium levels were available in 12 patients, none of which developed incident cardiomyopathy. Results: The mean age of the population with metal group (MoM and MoP) was 53 years, predominantly males. During the follow up period of 10 years, the cumulative incidence (KM curve probabilities) of low EF <=40% in our study population was 14% in metal group as compared to 5% in non-metal group (CoC and CoP), (p value 0.51). At 15 years of follow up, among 122 patients, there were16 deaths in the metal group (81) and only 2 deaths in the non-metal group (41) (p value 0.15). Conclusions: In conclusion, although the incidence of cardiomyopathy as well as mortality is low in patients with metal hip arthroplasty and not significantly, further studies maybe needed to assess its effect on diastolic dysfunction.


1994 ◽  
Vol 4 (2) ◽  
pp. 69-74
Author(s):  
P. Farsetti ◽  
R. Caterini ◽  
V. Barletta ◽  
A. E. Guarnieri ◽  
E. Ippolito

Thirty uncemented porous-coated anatomic (PCA) total hip prostheses were implanted in 27 patients. The average age at the time of surgery was 54 years, and the average follow-up was 4.5 years. The average hip rating score was 88 points. Three patients had thigh pain at follow-up and fifteen had a mild limp, related to a weakness of the gluteus medius and minimus. On radiographic examination, we observed a good bone ingrowth of the implant in all patients. No aseptic loosening was radiographically demonstrated. No relationship was found between pain in the thigh and the various radiographic parameters studied (ra-diodense lines, sclerosis, varus position of the stem).


1998 ◽  
Vol 8 (3) ◽  
pp. 138-144 ◽  
Author(s):  
B. Erdemli ◽  
I. Gurkan ◽  
B. Guzel ◽  
I. Cetin

We report the results of Kent hip revision arthroplasties performed in 5 patients with fractures of the femur associated with femoral loosening following total hip arthroplasty. The fractures occurred at an average of 40.4 months following the primary hip arthroplasty. The system of Merle D'Aubigné and Postel, as modified by Charnley, was used for the clinical evaluation. One to four years (mean, 2.6 years) after the revision operation, the clinical and radiographic results were satisfactory. With the help of the transfixion screws the Kent Hip prosthesis provides stable fixation and facilitates early mobilization, with its attendant advantages.


1996 ◽  
Vol 329 ◽  
pp. S187-S205 ◽  
Author(s):  
Peter F. Doorn ◽  
Joseph M. Mirra ◽  
Patricia A. Campbell ◽  
Harlan C. Amstutz

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