scholarly journals Chronic Rhinosinusitis in Cystic Fibrosis: Diagnosis and Medical Management

2019 ◽  
Vol 7 (2) ◽  
pp. 32 ◽  
Author(s):  
Chetan Safi ◽  
Zhong Zheng ◽  
Emily Dimango ◽  
Claire Keating ◽  
David Gudis
Keyword(s):  
Cystic Fibrosis ◽  
Chronic Rhinosinusitis ◽  
Medical Management ◽  
Sinus Disease ◽  
Medical Comorbidities

Chronic rhinosinusitis (CRS) is nearly ubiquitous in patients with cystic fibrosis (CF). CF CRS is a challenging entity to define, diagnose, and treat, as patients often have severe refractory sinus disease in addition to complex medical comorbidities. The purpose of this article is to review the literature on the medical management of CF CRS and determine how to best identify, diagnose, and manage CF CRS. Ultimately, the treatment of these patients requires a multi-disciplinary approach involving the pulmonologist and otolaryngologist.

scholarly journals Extensive Surgical and Comprehensive Postoperative Medical Management for Cystic Fibrosis Chronic Rhinosinusitis

2012 ◽  
Vol 26 (1) ◽  
pp. 70-75 ◽  
Author(s):  
Frank W. Virgin ◽  
Steven M. Rowe ◽  
Mary B. Wade ◽  
Amit Gaggar ◽  
Kevin J. Leon ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Chronic Rhinosinusitis ◽  
Medical Management

Medical management of chronic rhinosinusitis in cystic fibrosis: A systematic review

2013 ◽  
Vol 124 (6) ◽  
pp. 1308-1313 ◽  
Author(s):  
Jonathan Liang ◽  
Thomas Higgins ◽  
Stacey L. Ishman ◽  
Emily F. Boss ◽  
James R. Benke ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cystic Fibrosis ◽  
Chronic Rhinosinusitis ◽  
Medical Management

Correlations between cystic fibrosis genotype and sinus disease severity in chronic rhinosinusitis

2017 ◽  
Vol 128 (8) ◽  
pp. 1752-1758 ◽  
Author(s):  
Waleed M. Abuzeid ◽  
Changeun Song ◽  
Judd H. Fastenberg ◽  
Christina H. Fang ◽  
Noel Ayoub ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Chronic Rhinosinusitis ◽  
Disease Severity ◽  
Sinus Disease

Sinus Disease in Cystic Fibrosis

1995 ◽  
Vol 112 (5) ◽  
pp. P186-P186
Author(s):  
David E. Tunkel ◽  
Max M. April
Keyword(s):  
Cystic Fibrosis ◽  
Head And Neck ◽  
Medical Management ◽  
Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Educational Objectives ◽  
Sinus Disease

Educational objectives: To understand cystic fibrosis with regards to diagnosis, medical management, and head and neck manifestations and to understand the application of endoscopic sinus surgery techniques to the sinonasal pathology in patients with cystic fibrosis.

scholarly journals Risk of COVID-19 Infection Among Chronic Rhinosinusitis Patients Receiving Oral Corticosteroids

2021 ◽  
pp. 019459982110069
Author(s):  
Lauren E. Miller ◽  
Neil Bhattacharyya
Keyword(s):  
Conservative Treatment ◽  
Chronic Rhinosinusitis ◽  
Treatment Regimen ◽  
Medical Management ◽  
Steroid Use ◽  
Positive Diagnosis ◽  
Increased Risk ◽  
Significant Difference ◽  
Oral Corticosteroids

Chronic rhinosinusitis (CRS) management frequently comprises conservative treatment, including a combination of topical and oral corticosteroids (OCSs). However, in the midst of the coronavirus disease 2019 (COVID-19) pandemic, providers may have been reluctant to prescribe OCSs out of possible concern for an increased risk of contracting COVID-19 or developing more severe COVID-19 symptoms. This study thus sought to explore the association between the use of OCSs and the development of COVID-19 in patients with CRS. We found no statistically significant difference in the rates of patients with a positive diagnosis of COVID-19 who underwent an OCS treatment regimen compared to those who did not, both within 28 days ( P = .389) and 14 days ( P = .676) prior to the COVID-19 test. Given OCSs are often a major component of medical management of CRS, this study proves helpful in counseling patients on risks of steroid use in CRS treatment during the COVID-19 pandemic.

Paranasal Sinus Development in Chronic Sinusitis, Cystic Fibrosis, and Normal Comparison Population: A Computerized Tomography Correlation Study

1997 ◽  
Vol 11 (4) ◽  
pp. 275-282 ◽  
Author(s):  
Hung Jeff Kim ◽  
Ellen M. Friedman ◽  
Marcelle Sulek ◽  
Newton O. Duncan ◽  
Charles McCluggage
Keyword(s):  
Cystic Fibrosis ◽  
Maxillary Sinus ◽  
Paranasal Sinus ◽  
Chronic Sinusitis ◽  
Correlation Study ◽  
Uncinate Process ◽  
Ct Scans ◽  
Lateral Nasal Wall ◽  
Transverse Diameter ◽  
Sinus Disease

Chronic sinus disease in patients with and without cystic fibrosis may have an impact on the pattern of paranasal sinus pneumatization. Arrest of pneumatization has been reported in both of these conditions. To assess the development of the paranasal sinuses in relationship to chronic sinusitis and cystic fibrosis (CF), a retrospective review of coronal CT scans of the age-matched patients with no previous sinus disease, patients with chronic sinusitis, and cystic fibrosis patients was conducted. The patients’ ages ranged from 4 to 17 years. The maxillary sinus volume, anteroposterior diameter, and greatest transverse diameter and height were determined using image analysis software after the coronal CT scans were scanned into Macintosh computer. The size of the maxillary sinus increased with advancing age in the control and chronic sinusitis group, but not in the patients with cystic fibrosis. The patients with cystic fibrosis had a statistically significant smaller maxillary sinus size. Approximately 50% of the patients with chronic sinusitis had anatomic anomalies, the most common being paradoxical middle turbinates. The CT scans of CF patients were characterized by uncinate process demineralization and medial displacement of the lateral nasal wall in the middle meatus, and decreased maxillary sinus pneumatization.

The Impact of Medical Comorbidities on Patient Satisfaction in Chronic Rhinosinusitis

2021 ◽  
pp. 000348942110157
Author(s):  
Amarbir S. Gill ◽  
Joshua Hwang ◽  
Angela M. Beliveau ◽  
Jeremiah A. Alt ◽  
Edward Bradley Strong ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
Hearing Impairment ◽  
Chronic Rhinosinusitis ◽  
Medical Comorbidities ◽  
Patient Demographics ◽  
Significant Difference ◽  
Comorbidity Index ◽  
The Mean ◽  
Therapy Compliance ◽  
The Impact

Background: Patient satisfaction has a significant bearing on medical therapy compliance and patient outcomes. The purpose of this study was to (1) describe patient satisfaction, as characterized by the Patient Satisfaction Questionnaire-18 (PSQ-18), in the care of patients with chronic rhinosinusitis (CRS) and (2) analyze the impact of comorbidities on satisfaction using the functional comorbidity index (FCI). Methods: Patient demographics, disease severity measures, and PSQ-18 scores for patients with CRS presenting to a tertiary rhinology clinic between November 2019 and April 2020 were collected and analyzed. FCI was calculated retrospectively using the electronic medical record; individual comorbidities were tabulated. Spearman’s correlations followed by multivariate regression was used to assess the relationship between medical comorbidities and PSQ-18. Results: Sixty-nine patients met criteria for analysis. There were no significant differences in age, gender, and Sinonasal Outcomes Test-22 scores between CRS patients with (CRSwNP) and without (CRSsNP) nasal polyps. There was no significant difference in the mean FCI for patients with CRSwNP versus CRSsNP (5.1 and 4.3, respectively) ( P = .843). Similarly, there was no significant difference in the mean sum PSQ-18 score (78/100 in both) between these cohorts ( P = .148). The mean sum PSQ-18 score was not significantly associated with anxiety ( P = .728), depression ( P = .624), or FCI ( P = .282), but was significantly associated with hearing impairment ( P < .001). Conclusion: Patient satisfaction in the care of CRS is generally high with a diagnosis of comorbid hearing impairment demonstrating a negative association with satisfaction in this cohort.

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