scholarly journals A New Synthetic Route to Polyhydrogenated Pyrrolo[3,4-b]pyrroles by the Domino Reaction of 3-Bromopyrrole-2,5-Diones with Aminocrotonic Acid Esters

Molecules ◽  
2017 ◽  
Vol 22 (11) ◽  
pp. 2035
Author(s):  
Khidmet Shikhaliev ◽  
Artem Sabynin ◽  
Valeri Sekirin ◽  
Michael Krysin ◽  
Fedor Zubkov ◽  
...  
Author(s):  
Khidmet Shikhaliev ◽  
Artem Sabynin ◽  
Valeri Sekirin ◽  
Michael Krysin ◽  
Fedor Zubkov ◽  
...  

A new synthetic approach to polyfunctional hexahydropyrrolo[3,4-b]pyrroles was developed based on cyclization of N-arylbromomaleimides with aminocrotonic acid esters. A highly chemo- and stereoselective reaction is a Hantzsch-type domino process, involving the steps of initial nucleophilic C-addition or substitution and subsequent intramolecular nucleophilic addition without recyclyzation of imide cycle.


Tetrahedron ◽  
1970 ◽  
Vol 26 (18) ◽  
pp. 4419-4433 ◽  
Author(s):  
B.P. Gottikh ◽  
A.A. Krayevsky ◽  
N.B. Tarussova ◽  
P.P. Purygin ◽  
T.L. Tsilevich

1979 ◽  
Vol 6 (1-2) ◽  
pp. 329-329 ◽  
Author(s):  
Eberhard Wenschuh ◽  
Reinhard Fahsl

2022 ◽  
Author(s):  
Mahsa Ahmadian ◽  
Kurosh Rad-Moghadam ◽  
Arash Dehghanian ◽  
Majedeh Jafari

Fairly high yields of 2-aryl-3-nitrodibenzo[e,g]¬¬¬¬indoles were synthesized via a hitherto unreported domino-reaction of 9,10-phenanthrenequinone, ammonium acetate and β-nitrostyrenes in one pot. This novel three-component synthetic route is efficaciously catalysed by...


ChemInform ◽  
2007 ◽  
Vol 38 (28) ◽  
Author(s):  
Michael Schnuerch ◽  
Markus Holzweber ◽  
Marko D. Mihovilovic ◽  
Peter Stanetty

Author(s):  
Samiran Dhara ◽  
Subhadeep Ghosh ◽  
Asish R. Das

An expeditious synthetic route to access functionalized pyrrolo[2,1-b]quinazoline scaffolds has been achieved via domino ring opening cyclization (DROC) reactions of donor–acceptor (D–A) cyclopropanes and 2-amino(methyl)aniline derivatives.


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