scholarly journals Sister Mary Joseph’s nodule: an unusual but important physical finding characteristic of widespread internal malignancy

2013 ◽  
Vol 63 (615) ◽  
pp. 551-552 ◽  
Author(s):  
Simon Tso ◽  
Julia Brockley ◽  
Hilmi Recica ◽  
Andrew Ilchyshyn
2006 ◽  
Vol 5 (5) ◽  
pp. 256-258 ◽  
Author(s):  
Roni Dodiuk-Gad ◽  
Michael Ziv ◽  
David Loven ◽  
Jan Schafer ◽  
Ayelet Shani-Adir ◽  
...  

2021 ◽  
Author(s):  
Elroy Patrick Weledji ◽  
Mbachan Masoeli Takere ◽  
Joviale Christelle Maffo

Abstract Background: Sister Mary Joseph’s nodule is a rare but important physical finding as it is a sign of an advanced stage of malignancy.Case presentation: This is a case of an apparently clinically well but immunodeficient 62-year- old African woman whose main complaint was an enlarging violaceous discharging umbilical nodule. A focused history and physical examination complemented by an abdominal computerized tomography (CT) scan was suggestive of an umbilical cutaneous manifestation (Sister Mary Joseph’s nodule) of an underlying disseminated ovarian malignancy. This was confirmed histologically by an excision biopsy of the umbilical nodule.Conclusions: Sister Mary Joseph’s nodule is an important differential diagnosis for an umbilical nodular lesion as it is a sign of advanced malignancy with a generally poor prognosis.


2011 ◽  
Vol 86 (4 suppl 1) ◽  
pp. 118-120 ◽  
Author(s):  
Walter Augusto Pereira ◽  
Caio Rosa Humaire ◽  
Camila Simon Silva ◽  
Lucia Helena Gomes Fernandes

The umbilicus can be affected by various skin diseases including metastasis of internal malignancies, at which point it is known as Sister Mary Joseph's Nodule. The authors report a case of Sister Mary Joseph's Nodule as the first sign of internal malignancy and highlight the importance for the dermatologist to recognize the condition


2019 ◽  
Vol 11 (3) ◽  
pp. 268-272
Author(s):  
Andrew P. Sauvageau ◽  
Jacob Mojeski ◽  
Thomas W. Fiorica ◽  
Craig C. Miller

Erythema gyratum repens (EGR) is a rare paraneoplastic skin condition characterized by the eruption of expanding, concentric, erythematous patches and plaques. The condition may precede a symptomatic appearance of internal malignancy, and therefore provides a unique opportunity to prevent additional morbidity and mortality secondary to undetectable cancer growth. We report the case of a 71-year-old female patient clinically diagnosed with EGR and subsequently diagnosed with otherwise asymptomatic adenocarcinoma of the lung.


2021 ◽  
pp. 41-46
Author(s):  
Anum Aqsa ◽  
Sami Droubi ◽  
Shivantha Amarnath ◽  
Fady Haddad ◽  
Liliane Deeb

Metastasis to the colon from another primary internal malignancy is an untypical and a seldom reported entity. Direct visualization during colonoscopy is considered the gold standard of diagnosis. Pathologic diagnosis with immunohistochemical staining is essential to differentiate primary colorectal malignancy from secondary metastasis to the colon. We, hereby, present a case of a 53-year-old female status-post resection of left-sided papillary serous ovarian neoplasm who presented 2 years later with a single rectosigmoid intraluminal ulcerative mass imitating a primary colon cancer. Biopsies of the mass were consistent with metastasis from her primary ovarian carcinoma. We believe this case is unique because of the rarity of ovarian cancer metastasizing to the colon intraluminally rather than through direct locoregional invasion. Furthermore, it highlights the importance of considering secondary metastasis in patients with previous history of another primary internal malignancy.


1974 ◽  
Vol 83 (4) ◽  
pp. 550-554 ◽  
Author(s):  
Gary D. Becker ◽  
Alexander M. Wernicke

Four cases of gonococcal pharyngotonsillitis have been presented, along with a review of the world literature. This entity is most commonly seen in those individuals practicing fellatio, i.e., females and homosexual males. The infection may be passed to the newborn by the infected genitals of the mother during birth, to the infant from adult molestation, or among sexually promiscuous children. Most gonococcal pharyngeal infections result in a carrier state, and as such, are possible reservoirs of propagated infections. When symptomatic, the most frequent complaint is a sore throat. Physical finding among symptomatic patients reveal a wide spectrum ranging from mild hyperemia of the pharynx or tonsils, to exudative tonsillitis with tender cervical lymph nodes and moderate elevation of temperature. Most authorities agree that the preferred treatment is 4.8 million units of procaine penicillin G I.M., with one gm of probenecid by mouth thirty minutes before the injection. If allergic to penicillin, tetracycline should be given, 1.5 gm by mouth stat, then 0.5 gm four times a day for a total of 9 gm. A routine blood agar culture of the throat will not reveal the presence of the gonococcus. Thayer-Martin (or Transgrow) media must be used. Failure to detect pathogenic bacteria in a routine culture may lead to either no treatment or improper treatment of a gonococcal pharyngotonsillar infection. This may result in a carrier state, or even worse, to a disseminated gonococcal infection.


2010 ◽  
Vol 18 (1) ◽  
pp. 119-121 ◽  
Author(s):  
Nobuyuki Ozaki ◽  
Hiroshi Takamori ◽  
Hideo Baba

Surgery ◽  
2010 ◽  
Vol 147 (1) ◽  
pp. 167-168 ◽  
Author(s):  
Chun-Yi Liu ◽  
Chee-Chien Yong ◽  
Shih-Chung Wu ◽  
Chi-Yin Lin ◽  
Chao-Long Chen ◽  
...  

1991 ◽  
Vol 30 (1) ◽  
pp. 53-56 ◽  
Author(s):  
Heiichiro TAJIMA ◽  
Satoshi MITSUOKA ◽  
Ehji OHTSUKA ◽  
Yoshitomo NAKAMURA ◽  
Toshihiro NAKAYAMA ◽  
...  

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