Ophthalmic optics. Contact lenses. Ageing by exposure to UV and visible radiation (in vitro method)

1998 ◽  
2019 ◽  
Vol 42 (2) ◽  
pp. 178-184 ◽  
Author(s):  
Hendrik Walther ◽  
Lakshman. N. Subbaraman ◽  
Lyndon Jones

1979 ◽  
Vol 41 (03) ◽  
pp. 576-582
Author(s):  
A R Pomeroy

SummaryThe limitations of currently used in vitro assays of heparin have demonstrated the need for an in vivo method suitable for routine use.The in vivo method which is described in this paper uses, for each heparin preparation, four groups of five mice which are injected intravenously with heparin according to a “2 and 2 dose assay” procedure. The method is relatively rapid, requiring 3 to 4 hours to test five heparin preparations against a standard preparation of heparin. Levels of accuracy and precision acceptable for the requirements of the British Pharmacopoeia are obtained by combining the results of 3 to 4 assays of a heparin preparation.The similarity of results obtained the in vivo method and the in vitro method of the British Pharmacopoeia for heparin preparations of lung and mucosal origin validates this in vivo method and, conversely, demonstrates that the in vitro method of the British Pharmacopoeia gives a reliable estimation of the in vivo activity of heparin.


1991 ◽  
Vol 157 (5) ◽  
pp. 1125-1125
Author(s):  
D J Eschelman ◽  
A J Greenfield ◽  
D T Gibbens

1986 ◽  
Vol 5 (4) ◽  
pp. 309-317 ◽  
Author(s):  
Paul S. Imperia ◽  
Hillard M. Lazarus ◽  
Roberte Botti ◽  
Jonathan H. Lass
Keyword(s):  

2010 ◽  
Vol 87 (4) ◽  
pp. 363-369 ◽  
Author(s):  
Robert L. Magaletta ◽  
Suzanne N. DiCataldo ◽  
Dong Liu ◽  
Hong Laura Li ◽  
Rajendra P. Borwankar ◽  
...  

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