Water pipe tobacco � Determination of carbon monoxide in the vapour phase of water pipe tobacco smoke � NDIR method

2019 ◽  
CJEM ◽  
2012 ◽  
Vol 14 (01) ◽  
pp. 57-59 ◽  
Author(s):  
Giovanna La Fauci ◽  
Giora Weiser ◽  
Ivan P. Steiner ◽  
Itai Shavit

ABSTRACT Narghile (water pipe, hookah, shisha, goza, hubble bubble, argeela) is a traditional method of tobacco use. In recent years, its use has increased worldwide, especially among young people. Narghile smoking, compared to cigarette smoking, can result in more smoke exposure and greater levels of carbon monoxide (CO). We present an acutely confused adolescent patient who had CO poisoning after narghile tobacco smoking. She presented with syncope and a carboxyhemoglobin level of 24% and was treated with hyperbaric oxygen. Five additional cases of CO poisoning after narghile smoking were identified during a literature search, with carboxyhemoglobin levels of 20 to 30%. Each patient was treated with oxygen supplementation and did well clinically. In light of the increasing popularity of narghile smoking, young patients presenting with unexplained confusion or nonspecific neurologic symptoms should be asked specifically about this exposure, followed by carboxyhemoglobin measurement.


Author(s):  
J. Johnson ◽  
M. A. Nisbet

AbstractCigarette smoke has been shown to contain free radicals in both the vapour and particulate phases. The present investigation was undertaken to find out whether these radicals could initiate or promote the formation of radical peroxides which might in turn lead to lipid peroxidation. To investigate this, a system involving the coupled oxidation of b-carotene and linoleic acid was utilized. In this coupled reaction, b-carotene is destroyed through oxidation by free peroxy radicals. The system can therefore be used as a convenient detector of auto-oxidative mechanisms in which peroxide radicals participate, as well as provide an assay for antioxidants, since in their presence oxidative destruction of b-carotene is blocked. Our results show that smoke did not contribute to the oxidative destruction of b-carotene but rather behaved as an antioxidant. Both smoke vapour and particulate matter were found to be highly antioxidant. A number of pure vapour phase components were tested and the bulk of antioxidant activity was found to be due to HCN. Smoke condensates from different tobacco types were compared and differentiated according to their relative efficiencies of antioxidant activities. For comparison, units of antioxidant activity were expressed as rate of change of optical density with time. The highest antioxidant activities were obtained with air-, flue-cured (cut) and perique tobaccos. Pipe tobacco had the least activity while cigar and flue-cured (granulated), stem and sheet tobaccos had intermediate values. Tests done on smoke fractions derived from the fractionation of total condensate revealed that antioxidant activity resided largely in the neutral and water-insoluble acid fractions with virtually no activity in the basic fractions. The mode of antioxidant action of tobacco smoke is discussed in terms of free-radical mechanisms.


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