Faculty Opinions recommendation of Localization of Fas ligand in cytoplasmic granules of CD8+ cytotoxic T lymphocytes and natural killer cells: participation of Fas ligand in granule exocytosis model of cytotoxicity.

Author(s):  
Gillian Griffiths
2013 ◽  
pp. 215-227
Author(s):  
Stephen L. Nutt ◽  
Sebastian Carotta ◽  
Axel Kallies ◽  
Gabrielle T. Belz

Physiology ◽  
1988 ◽  
Vol 3 (5) ◽  
pp. 211-216
Author(s):  
JD-E Young ◽  
ZA Cohn

Subsets of lymphocytes, known as cytotoxic T lymphocytes or natural killer cells, are potent killers of target cells. These immune cells have large granules in their cytoplasm containing cytotoxic peptides and other factors. Several of these molecules have been isolated and their functions elucidated.


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