Faculty Opinions recommendation of A 6-month, randomized, double-masked, placebo-controlled study evaluating the effects of the protein kinase C-beta inhibitor ruboxistaurin on skin microvascular blood flow and other measures of diabetic peripheral neuropathy.

Microvascular Blood Flow ◽

Controlled Study ◽

Kinase C ◽

A 6-Month, Randomized, Double-Masked, Placebo-Controlled Study Evaluating the Effects of the Protein Kinase C- Inhibitor Ruboxistaurin on Skin Microvascular Blood Flow and Other Measures of Diabetic Peripheral Neuropathy

Diabetes Care ◽

10.2337/dc06-1699 ◽

2007 ◽

Vol 30 (4) ◽

pp. 896-902 ◽

Cited By ~ 84

Author(s):

C. M. Casellini ◽

P. M. Barlow ◽

A. L. Rice ◽

M. Casey ◽

K. Simmons ◽

...

Keyword(s):

Blood Flow ◽

Protein Kinase C ◽

Peripheral Neuropathy ◽

Protein Kinase ◽

Microvascular Blood Flow ◽

Controlled Study ◽

Kinase C ◽

Protein Kinase C Inhibitor

Endothelial and neural regulation of skin microvascular blood flow in patients with diabetic peripheral neuropathy: effect of treatment with the isoform-specific protein kinase C β inhibitor, ruboxistaurin

Journal of Diabetes and its Complications ◽

10.1016/j.jdiacomp.2007.07.002 ◽

2008 ◽

Vol 22 (2) ◽

pp. 88-95 ◽

Cited By ~ 21

Author(s):

Belinda Brooks ◽

Carol Delaney-Robinson ◽

Lynda Molyneaux ◽

Dennis K. Yue

Keyword(s):

Blood Flow ◽

Protein Kinase C ◽

Peripheral Neuropathy ◽

Protein Kinase ◽

Specific Protein ◽

Microvascular Blood Flow ◽

Kinase C ◽

Effect Of Treatment ◽

Specific Protein Kinase

Protein kinase C beta inhibitor prevents diabetic peripheral neuropathy, but not histopathological abnormalities of retina in Spontaneously Diabetic Torii rat

Diabetes Obesity and Metabolism ◽

10.1111/j.1463-1326.2009.01082.x ◽

2009 ◽

Vol 11 (11) ◽

pp. 1084-1087 ◽

Cited By ~ 15

Author(s):

T. Sasase ◽

H. Morinaga ◽

T. Abe ◽

K. Miyajima ◽

T. Ohta ◽

...

Keyword(s):

Protein Kinase C ◽

Peripheral Neuropathy ◽

Protein Kinase ◽

Kinase C ◽

Treatment of symptomatic diabetic peripheral neuropathy with the protein kinase C β-inhibitor ruboxistaurin mesylate during a 1-year, randomized, placebo-controlled, double-blind clinical trial

Clinical Therapeutics ◽

10.1016/j.clinthera.2005.08.001 ◽

2005 ◽

Vol 27 (8) ◽

pp. 1164-1180 ◽

Cited By ~ 119

Author(s):

Aaron I. Vinik ◽

Vera Bril ◽

Peter Kempler ◽

William J. Litchy ◽

Solomon Tesfaye ◽

...

Keyword(s):

Clinical Trial ◽

Protein Kinase C ◽

Peripheral Neuropathy ◽

Protein Kinase ◽

Double Blind ◽

Kinase C ◽

Double Blind Clinical Trial

Activating transcription factor 3 modulates protein kinase C epsilon activation in diabetic peripheral neuropathy

Journal of Pain Research ◽

10.2147/jpr.s186699 ◽

2019 ◽

Vol Volume 12 ◽

pp. 317-326

Author(s):

Ying-Shuang Chang ◽

Hung-Wei Kan ◽

Yu-Lin Hsieh

Keyword(s):

Transcription Factor ◽

Protein Kinase C ◽

Peripheral Neuropathy ◽

Protein Kinase ◽

Activating Transcription Factor 3 ◽

Kinase C ◽

Protein Kinase C Epsilon ◽

Activating Transcription Factor ◽

Transcription Factor 3

Association of two genetic markers within the protein kinase C beta gene with type 2 diabetes mellitus

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-2005-862960 ◽

2005 ◽

Vol 113 (S 1) ◽

Author(s):

MA Osterhoff ◽

M Herrmann ◽

M Lazdins ◽

S Kaiser ◽

R Assert ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Protein Kinase C ◽

Protein Kinase ◽

Genetic Markers ◽

Kinase C ◽

Beta Gene ◽

Überexpression von Protein Kinase C beta im Skelettmuskel führt bei C57Bl/6 Mäusen zu Insulinresistenz

Diabetologie und Stoffwechsel ◽

10.1055/s-2006-943750 ◽

2006 ◽

Vol 1 (S 1) ◽

Author(s):

AM Hennige ◽

E Metzinger ◽

R Lammers ◽

MA Schneider ◽

R Lehmann ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kinase C ◽

Untersuchung der Protein Kinase C beta II-Phosphorylierungszustände mittels zweidimensionalem Immunoblot

Aktuelle Ernährungsmedizin ◽

10.1055/s-2006-946781 ◽

2006 ◽

Vol 31 (03) ◽

Author(s):

S Richter ◽

M Osterhoff ◽

A Pfeiffer

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kinase C ◽

Faculty Opinions recommendation of Phase I dose escalation and pharmacokinetic study of enzastaurin, an oral protein kinase C beta inhibitor, in patients with advanced cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1043078.492991 ◽

2006 ◽

Author(s):

Jeffrey Evans

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Phase I ◽

Advanced Cancer ◽

Pharmacokinetic Study ◽

Dose Escalation ◽

Kinase C ◽

1,25-Dihydroxyvitamin D3 translocates protein kinase C beta to nucleus and enhances plasma membrane association of protein kinase C alpha in renal epithelial cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)41856-4 ◽

1994 ◽

Vol 269 (5) ◽

pp. 3257-3264 ◽

Cited By ~ 1

Author(s):

M. Simboli-Campbell ◽

A. Gagnon ◽

D.J. Franks ◽

J. Welsh

Keyword(s):

Plasma Membrane ◽

Protein Kinase C ◽

Protein Kinase ◽

Epithelial Cells ◽

Membrane Association ◽

Dihydroxyvitamin D3 ◽

Renal Epithelial Cells ◽

1,25 Dihydroxyvitamin D3 ◽

Kinase C ◽