Faculty Opinions recommendation of Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: a controlled randomized trial.

Author(s):  
Thomas Ullman ◽  
Jenny Sauk

2013 ◽  
Vol 144 (5) ◽  
pp. S-21 ◽  
Author(s):  
Edoardo Savarino ◽  
Giorgia Bodini ◽  
Pietro Dulbecco ◽  
Elisa Marabotto ◽  
Lorenzo Assandri ◽  
...  


2008 ◽  
Vol 135 (4) ◽  
pp. 1123-1129 ◽  
Author(s):  
Geert R. D'Haens ◽  
Severine Vermeire ◽  
Gert Van Assche ◽  
Maja Noman ◽  
Isolde Aerden ◽  
...  


2013 ◽  
Vol 45 ◽  
pp. S94-S95 ◽  
Author(s):  
E. Savarino ◽  
G. Bodini ◽  
P. Dulbecco ◽  
L. Assandri ◽  
L. Bruzzone ◽  
...  


2018 ◽  
Vol 18 (12) ◽  
pp. 979-988 ◽  
Author(s):  
Antonio Di Sario ◽  
Paola Sassaroli ◽  
Luigi Daretti ◽  
Giulia Annulli ◽  
Laura Schiada ◽  
...  


Digestion ◽  
2021 ◽  
pp. 1-9
Author(s):  
Akihiro Yamada ◽  
Yuga Komaki ◽  
Fukiko Komaki ◽  
Haider Haider ◽  
Dejan Micic ◽  
...  

<b><i>Background and Aims:</i></b> Vitamin D deficiency has been associated with disease activity in Crohn’s disease (CD). We assessed whether there is a correlation between vitamin D levels and the risk of postoperative recurrence in CD. <b><i>Methods:</i></b> CD patients who underwent surgery were identified from a prospectively maintained database at the University of Chicago. The primary endpoint was the correlation of serum 25-hydroxy vitamin D levels measured at 6–12 months after surgery and the proportion of patients in endoscopic remission, defined as a simple endoscopic score for CD of 0. Clinical, biological (C-reactive protein), and histologic recurrences were also studied. <b><i>Results:</i></b> Among a total of 89 patients, 17, 46, and 26 patients had vitamin D levels of &#x3c;15, 15–30, and &#x3e;30 ng/mL, respectively. Patients with higher vitamin D levels were significantly more likely to be in endoscopic remission compared to those with lower levels (23, 42, and 67% in ascending tertile order; <i>p</i> = 0.028). On multivariate analysis, vitamin D &#x3e;30 ng/mL (odds ratio [OR] 0.22, 95% confidence interval [CI] 0.07–0.66, <i>p</i> = 0.006) and anti-tumor necrosis factor agent treatment (OR 0.25, 95% CI 0.08–0.83, <i>p</i> = 0.01) were associated with reduced risk of endoscopic recurrence. Rates of clinical, biological, and histologic remission trended to be higher in patients with higher vitamin D levels (<i>p</i> = 0.17, 0.55, 0.062, respectively). <b><i>Conclusion:</i></b> In the present study, higher vitamin D level was associated with lower risk of postoperative endoscopic CD recurrence. Further, studies are warranted to assess the role of vitamin D in postoperative CD recurrence.



2002 ◽  
Vol 34 ◽  
pp. A84
Author(s):  
A. Resegotti ◽  
B. Demarchi ◽  
G.I. Avagnina ◽  
N. Sapone ◽  
A. Giustetto ◽  
...  


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