Faculty Opinions recommendation of Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: a long-term follow-up.

2009 ◽  
Author(s):  
Gilberto Schwartsmann ◽  
Fabio Leal
Keyword(s):  
Breast Cancer ◽  
Bone Marrow ◽  
Overall Survival ◽  
Cancer Patients ◽  
Primary Breast Cancer ◽  
Breast Cancer Patients ◽  
Long Term Follow Up ◽  
Oral Clodronate

Bone Marrow Micrometastases in Breast Cancer Patients: A Long-Term Follow-up Study

2008 ◽  
Vol 2 ◽  
pp. 117955490800200
Author(s):  
Annamaria Molino ◽  
Monica Giovannini ◽  
Rocco Micciolo ◽  
Alessandra Auriemma ◽  
Elena Fiorio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Marrow ◽  
Overall Survival ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Primary Surgery ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Disease Free

In 125 early breast cancer patients who underwent multiple bone marrow aspirates, there was no significant difference in terms of disease-free and overall survival after a median follow-up of 163 months between the patients with or without micrometastasis at the time of primary surgery. However, when the time-dependent evolution of the bone marrow aspirates was taken into account, some evidence for a longer disease-free and overall survival was found for the patients with negative bone marrow

Outcome of primary-breast-cancer patients with micrometastases: a long-term follow-up study

The Lancet ◽  
1999 ◽  
Vol 354 (9174) ◽  
pp. 197-202 ◽  
Author(s):  
Janine L Mansi ◽  
Helen Gogas ◽  
Judith M Biss ◽  
Jean-Claude Gazet ◽  
Uta Berger ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Primary Breast Cancer ◽  
Breast Cancer Patients ◽  
Follow Up Study ◽  
Long Term Follow Up

Is Breast Cancer Ever Cured? Follow-Up Study of 5623 Breast Cancer Patients

1991 ◽  
Vol 77 (6) ◽  
pp. 465-467 ◽  
Author(s):  
Stefano Ciatto ◽  
Rita Bonardi
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Systemic Disease ◽  
Cancer Death ◽  
Breast Cancer Patients ◽  
Death Rates ◽  
Breast Cancer Death ◽  
Long Term Follow Up

The authors evaluated 5623 cases of primary breast cancer followed for 1 to 21 years. Overall and breast cancer death rates were determined and compared to expected rates. Breast cancer patients showed overall and breast cancer death rates significantly higher than expected and which persisted at long-term follow-up. The observed/expected overall death ratios for follow-up periods of 0–5, 6–10, 11–15 or 16–20 years were 3.61, 2.55, 1.60 and 2.11, respectively. Death rates from breast cancer at 5, 10, 15 and 20 years were 20%, 32%, 40% and 48% respectively. The evidence of a persistent excess mortality even after long-term follow-up suggests the hypothesis that breast cancer is a systemic disease when clinically diagnosed. This study provided no evidence of a « clinical » cure for breast cancer patients. Even for N- patients the 5, 10, 15 and 20 year death rates from breast cancer were 12%, 20%, 28% and 38%, respectively. N- breast cancer, which is currently considered as a localized disease cured by surgery in most cases, would be better regarded to as a slow-growing metastatic disease, although « personal » cure may be achieved in many subjects dying of causes other than breast cancer.

Brachial Plexopathy After Postoperative Radiotherapy of Breast Cancer Patients: A Long-Term Follow-up

2000 ◽  
Vol 39 (3) ◽  
pp. 373-382 ◽  
Author(s):  
Silvia Johansson ◽  
Hans Svensson ◽  
Lars-Gunnar Larsson ◽  
Juliana Denekamp
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Postoperative Radiotherapy ◽  
Brachial Plexopathy ◽  
Breast Cancer Patients ◽  
Long Term Follow Up
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