Faculty Opinions recommendation of UVA1 induces cyclobutane pyrimidine dimers but not 6-4 photoproducts in human skin in vivo.

2012 ◽  
Author(s):  
Mary Norval
Keyword(s):  
Human Skin ◽  
Cyclobutane Pyrimidine Dimers ◽  
Pyrimidine Dimers

scholarly journals UVA1 Induces Cyclobutane Pyrimidine Dimers but Not 6-4 Photoproducts in Human Skin In Vivo

2012 ◽  
Vol 132 (2) ◽  
pp. 394-400 ◽  
Author(s):  
Angela Tewari ◽  
Robert P. Sarkany ◽  
Antony R. Young
Keyword(s):  
Human Skin ◽  
Cyclobutane Pyrimidine Dimers ◽  
Pyrimidine Dimers

scholarly journals Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation

2006 ◽  
Vol 103 (37) ◽  
pp. 13765-13770 ◽  
Author(s):  
S. Mouret ◽  
C. Baudouin ◽  
M. Charveron ◽  
A. Favier ◽  
J. Cadet ◽  
...  
Keyword(s):  
Human Skin ◽  
Dna Lesions ◽  
Cyclobutane Pyrimidine Dimers ◽  
Pyrimidine Dimers ◽  
Uva Radiation

Assessment of cyclobutane pyrimidine dimers by digital photography in human skin

2011 ◽  
Vol 373 (1-2) ◽  
pp. 240-246 ◽  
Author(s):  
Onno ten Berge ◽  
Sara G.A. van Velsen ◽  
Barbara Giovannone ◽  
Carla A.F.M. Bruijnzeel-Koomen ◽  
Edward F. Knol ◽  
...  
Keyword(s):  
Human Skin ◽  
Digital Photography ◽  
Cyclobutane Pyrimidine Dimers ◽  
Pyrimidine Dimers

Differential repair of UVB-induced cyclobutane pyrimidine dimers in cultured human skin cells and whole human skin

DNA Repair ◽  
2008 ◽  
Vol 7 (5) ◽  
pp. 704-712 ◽  
Author(s):  
Stéphane Mouret ◽  
Marie Charveron ◽  
Alain Favier ◽  
Jean Cadet ◽  
Thierry Douki
Keyword(s):  
Human Skin ◽  
Cyclobutane Pyrimidine Dimers ◽  
Skin Cells ◽  
Pyrimidine Dimers ◽  
Human Skin Cells

scholarly journals Nucleotide excision repair by dual incisions in plants

2016 ◽  
Vol 113 (17) ◽  
pp. 4706-4710 ◽  
Author(s):  
Fazile Canturk ◽  
Muhammet Karaman ◽  
Christopher P. Selby ◽  
Michael G. Kemp ◽  
Gulnihal Kulaksiz-Erkmen ◽  
...  
Keyword(s):  
Nucleotide Excision Repair ◽  
Excision Repair ◽  
Plant Genome ◽  
Cyclobutane Pyrimidine Dimers ◽  
Repair Gene ◽  
Phosphodiester Bonds ◽  
Pyrimidine Dimers ◽  
Nucleotide Excision ◽  
Dual Incision

Plants use light for photosynthesis and for various signaling purposes. The UV wavelengths in sunlight also introduce DNA damage in the form of cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts [(6-4)PPs] that must be repaired for the survival of the plant. Genome sequencing has revealed the presence of genes for both CPD and (6-4)PP photolyases, as well as genes for nucleotide excision repair in plants, such asArabidopsisand rice. Plant photolyases have been purified, characterized, and have been shown to play an important role in plant survival. In contrast, even though nucleotide excision repair gene homologs have been found in plants, the mechanism of nucleotide excision repair has not been investigated. Here we used the in vivo excision repair assay developed in our laboratory to demonstrate thatArabidopsisremoves CPDs and (6-4)PPs by a dual-incision mechanism that is essentially identical to the mechanism of dual incisions in humans and other eukaryotes, in which oligonucleotides with a mean length of 26–27 nucleotides are removed by incising ∼20 phosphodiester bonds 5′ and 5 phosphodiester bonds 3′ to the photoproduct.

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