Faculty Opinions recommendation of Ocular hypotensive efficacy, safety and systemic absorption of AR-12286 ophthalmic solution in normal volunteers.

2013 ◽  
Author(s):  
Alon Harris ◽  
Annahita Amireskandari
Keyword(s):  
Ophthalmic Solution ◽  
Systemic Absorption ◽  
Normal Volunteers

Ocular Hypotensive Safety and Systemic Absorption of AR-13324 Ophthalmic Solution in Normal Volunteers

2015 ◽  
Vol 159 (5) ◽  
pp. 980-985.e1 ◽  
Author(s):  
Brian Levy ◽  
Nancy Ramirez ◽  
Gary D. Novack ◽  
Casey Kopczynski
Keyword(s):  
Ophthalmic Solution ◽  
Systemic Absorption ◽  
Normal Volunteers

Ocular hypotensive efficacy, safety and systemic absorption of AR-12286 ophthalmic solution in normal volunteers

2013 ◽  
Vol 97 (5) ◽  
pp. 567-572 ◽  
Author(s):  
Casey Kopczynski ◽  
Gary D Novack ◽  
Dennis Swearingen ◽  
Thomas van Haarlem
Keyword(s):  
Ophthalmic Solution ◽  
Systemic Absorption ◽  
Normal Volunteers

Systemic Absorption of Topical Lidocaine in Normal Volunteers, Patients with Post-Herpetic Neuralgia, and Patients with Acute Herpes Zoster

2002 ◽  
Vol 91 (5) ◽  
pp. 1343-1350 ◽  
Author(s):  
Bryan J. Campbell ◽  
Michael Rowbotham ◽  
Pamela Stitzlein Davies ◽  
Peyton Jacob ◽  
Neal L. Benowitz
Keyword(s):  
Herpes Zoster ◽  
Systemic Absorption ◽  
Post Herpetic Neuralgia ◽  
Normal Volunteers ◽  
Acute Herpes Zoster ◽  
Topical Lidocaine

Disposition and metabolism of the flavonoid chrysin in normal volunteers

2001 ◽  
Vol 51 (2) ◽  
pp. 143-146 ◽  
Author(s):  
T. Walle, ◽  
Y. Otake, ◽  
J. A. Brubaker, ◽  
U. K. Walle ◽  
P. V. Halushka
Keyword(s):  
Normal Volunteers

A Sex Difference in the Bleeding Time

1980 ◽  
Vol 43 (02) ◽  
pp. 131-132 ◽  
Author(s):  
Barbara Bain ◽  
T Forster
Keyword(s):  
Platelet Count ◽  
Blood Vessels ◽  
Sex Difference ◽  
Bleeding Time ◽  
Platelet Aggregability ◽  
Normal Volunteers ◽  
Detectable Difference

SummaryThe bleeding time by a modified Ivy technique was estimated on 128 normal volunteers, 59 men and 69 women. The bleeding time was found to be significantly longer in women than men (p<.001). This was not attributable to a difference in platelet count nor to any detectable difference in platelet aggregability. It is likely that a difference in blood vessels or supporting tissues is responsible for the observed difference.

Determination of Plasminogen in Clots and Thrombi

1966 ◽  
Vol 16 (01/02) ◽  
pp. 038-050 ◽  
Author(s):  
Ulla Hedner ◽  
Inga Marie Nilsson ◽  
B Robertson
Keyword(s):  
Mean Value ◽  
Main Mechanism ◽  
Clot Lysis ◽  
Post Mortem ◽  
Digestion Time ◽  
Normal Volunteers ◽  
Casein Solution ◽  
The Mean

SummaryThe plasminogen content was determined by a casein method in plasma and serum from 20 normal volunteers. The mean plasminogen content was found to be 10.1 ACU (the arbitrary caseinolytic unit defined in such a way that using a 3% casein solution and a digestion time of 20 min. at 37°C, 10 ACU gave an extinction of 0.300). No difference between serum and plasma regarding the plasminogen content was found.Plasminogen was determined in drained and drained plus washed clots prepared from 2 ml plasma. The highest values found in the drained clots were 0.9 ACU/clot and 0.2 ACU/clot in the drained plus washed clots.Plasminogen was also determined in drained and drained plus washed clots prepared from plasma with added purified plasminogen. The plasminogen was recovered in the washing fluid. According to these tests, then, purified added plasminogen is washed out of the clots.The plasminogen content of 20 thrombi obtained post mortem was also determined. The mean value was found to be 0.7 ACU/cm thrombus. Judging from our results, the “intrinsic clot lysis theory” is not the main mechanism of clot dissolution.

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