Faculty Opinions recommendation of Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

2013 ◽  
Author(s):  
C Michael DiPersio
Keyword(s):  
Tumor Formation ◽  
Skin Tumor ◽  
Epidermal Turnover ◽  
Slow Cycling

scholarly journals Loss of integrin  3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells

2012 ◽  
Vol 109 (52) ◽  
pp. 21468-21473 ◽  
Author(s):  
N. Sachs ◽  
P. Secades ◽  
L. van Hulst ◽  
M. Kreft ◽  
J.-Y. Song ◽  
...  
Keyword(s):  
Tumor Formation ◽  
Skin Tumor ◽  
Epidermal Turnover ◽  
Slow Cycling

Preventive effect of chemical peeling on ultraviolet induced skin tumor formation

2010 ◽  
Vol 60 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Mohamed Abdel-Daim ◽  
Yoko Funasaka ◽  
Tsuneyoshi Kamo ◽  
Masahiko Ooe ◽  
Hiroshi Matsunaka ◽  
...  
Keyword(s):  
Tumor Formation ◽  
Skin Tumor ◽  
Preventive Effect ◽  
Chemical Peeling

Hair Follicle Stem Cells: Their Location, Role in Hair Cycle, and Involvement in Skin Tumor Formation.

1993 ◽  
Vol 101 (s1) ◽  
pp. 16S-26S ◽  
Author(s):  
Robert M. Lavker ◽  
Stanley Miller ◽  
Caroline Wilson ◽  
George Cotsarelis ◽  
Zhi-Gang Wei ◽  
...  
Keyword(s):  
Stem Cells ◽  
Hair Follicle ◽  
Tumor Formation ◽  
Skin Tumor ◽  
Hair Cycle ◽  
Hair Follicle Stem Cells ◽  
Follicle Stem Cells

scholarly journals Overexpression of TC-PTP in murine epidermis attenuates skin tumor formation

Oncogene ◽  
2020 ◽  
Vol 39 (21) ◽  
pp. 4241-4256
Author(s):  
Mihwa Kim ◽  
Liza D. Morales ◽  
Cheol Jung Lee ◽  
Serena A. Olivarez ◽  
Woo Jin Kim ◽  
...  
Keyword(s):  
Tumor Formation ◽  
Skin Tumor

Effects of Acute and Subchronic Exposure of Topically Applied Fullerene Extracts on the Mouse Skin

1993 ◽  
Vol 9 (4) ◽  
pp. 623-630 ◽  
Author(s):  
Mark A. Nelson ◽  
Frederick E. Domann ◽  
G. Tim Bowden ◽  
Stephen B. Hooser ◽  
Quintus Fernando ◽  
...  
Keyword(s):  
Dna Synthesis ◽  
Ornithine Decarboxylase ◽  
Mouse Skin ◽  
Tumor Formation ◽  
Skin Tumor ◽  
Toxic Effects ◽  
Exposure Level ◽  
Decarboxylase Activity ◽  
Ornithine Decarboxylase Activity ◽  
Acute Toxic

The recent discovery that fullerenes (C60) can be produced in macroscopic quantities has sparked much interest in the chemistry of this unusual molecule. Concerns have also arose about the potential carcinogenic effects of this molecule. We have addressed the potential acute and subchronic toxic effects of fullerenes applied in benzene on the mouse skin. The acute toxic effects measured in this study included epidermal DNA synthesis and the induction of ornithine decarboxylase activity in the epidermis. At the topical dose of fullerenes used in these studies (i.e., 200 ug), we found no effect on either DNA synthesis or ornithine decarboxylase activity over a 72 hour time course after treatment. The subchronic effects of the fullerenes as a mouse skin tumor promoter was assessed by repeatedly applying the chemical to the skin after initiation with the polycyclic aromatic hydrocarbon, 7,12-dimethlybenz-anthracene (DMBA). Repeated administration of the fullerenes for up to 24 weeks post-initiation did not result in either benign or malignant skin tumor formation, whereas promotion with the phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA) resulted in the formation of benign skin tumors. Our data indicate that fullerenes applied in benzene at a likely industrial exposure level do not cause acute toxic effects on the mouse skin epidermis.

scholarly journals Energy Metabolism Rewiring Precedes UVB-Induced Primary Skin Tumor Formation

Cell Reports ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3621-3634 ◽  
Author(s):  
Mohsen Hosseini ◽  
Léa Dousset ◽  
Walid Mahfouf ◽  
Martin Serrano-Sanchez ◽  
Isabelle Redonnet-Vernhet ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Tumor Formation ◽  
Skin Tumor

Skin tumor formation in human papillomavirus 8 transgenic mice is associated with a deregulation of oncogenic miRNAs and their tumor suppressive targets

2011 ◽  
Vol 64 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Martin Hufbauer ◽  
Daliborka Lazić ◽  
Markus Reinartz ◽  
Baki Akgül ◽  
Herbert Pfister ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Transgenic Mice ◽  
Tumor Formation ◽  
Skin Tumor ◽  
Oncogenic Mirnas
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