Faculty Opinions recommendation of A single intravenous dose of ivabradine, a novel I(f) inhibitor, lowers heart rate but does not depress left ventricular function in patients with left ventricular dysfunction.

Small infants with severe left ventricular dysfunction (LVD) carry a poor prognosis with limited therapeutic options. Although mechanical support and heart transplantation are definitive therapies, improvement of left ventricular function with reversible pulmonary artery banding (rPAB) has been described. We report two cases of LVD treated with rPAB. One was successfully temporized, and one progressed to requiring transplantation, indicating that appropriate patient selection is critical to this technique's success.

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Accuracy of the automated assessment of left ventricular function with gated perfusion SPECT in the presence of perfusion defects and left ventricular dysfunction: Correlation with equilibrium radionuclide ventriculography and echocardiography

Journal of Nuclear Cardiology ◽

10.1067/mnc.2000.105279 ◽

2000 ◽

Vol 7 (4) ◽

pp. 301-311 ◽

Cited By ~ 44

Author(s):

T CHUA ◽

L YIN ◽

T THIANG ◽

T CHOO ◽

D PING ◽

...

Keyword(s):

Left Ventricular Function ◽

Ventricular Function ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Radionuclide Ventriculography ◽

Left Ventricular ◽

Automated Assessment ◽

Gated Perfusion Spect ◽

Perfusion Spect ◽

Perfusion Defects

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Estimation of Left Ventricular Function in Right Ventricular Volume and Pressure Overload. Detection of Early Left Ventricular Dysfunction by Tei Index.

Japanese Heart Journal ◽

10.1536/jhj.40.145 ◽

1999 ◽

Vol 40 (2) ◽

pp. 145-154 ◽

Cited By ~ 29

Author(s):

Won H. KIM ◽

Yutaka OTSUJI ◽

James B. SEWARD ◽

Chuwa TEI

Keyword(s):

Left Ventricular Function ◽

Right Ventricular ◽

Ventricular Function ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Pressure Overload ◽

Ventricular Volume ◽

Left Ventricular ◽

Right Ventricular Volume ◽

Tei Index

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Interferon-β Treatment Eliminates Cardiotropic Viruses and Improves Left Ventricular Function in Patients With Myocardial Persistence of Viral Genomes and Left Ventricular Dysfunction

Circulation ◽

10.1161/01.cir.0000072766.67150.51 ◽

2003 ◽

Vol 107 (22) ◽

pp. 2793-2798 ◽

Cited By ~ 344

Author(s):

Uwe Kühl ◽

Matthias Pauschinger ◽

Peter Lothar Schwimmbeck ◽

Bettina Seeberg ◽

Conny Lober ◽

...

Keyword(s):

Left Ventricular Function ◽

Ventricular Function ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Left Ventricular ◽

Interferon Β ◽

Viral Genomes ◽

Cardiotropic Viruses

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Catheter Ablation of Atrial Fibrillation Improves Left Ventricular Function in Patients with Left Ventricular Dysfunction

Journal of Cardiac Failure ◽

10.1016/j.cardfail.2014.06.257 ◽

2014 ◽

Vol 20 (8) ◽

pp. S91-S92

Author(s):

Arun Kanmanthareddy ◽

Avanija R. Buddam ◽

Madhu Reddy ◽

Sandeep Koripalli ◽

Ajay Vallakati ◽

...

Keyword(s):

Atrial Fibrillation ◽

Catheter Ablation ◽

Left Ventricular Function ◽

Ventricular Function ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Left Ventricular

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Left ventricular function in experimental volume overload hypertrophy

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1989.256.4.h974 ◽

1989 ◽

Vol 256 (4) ◽

pp. H974-H981 ◽

Cited By ~ 14

Author(s):

B. A. Carabello ◽

K. Nakano ◽

W. Corin ◽

R. Biederman ◽

J. F. Spann

Keyword(s):

Mitral Regurgitation ◽

Left Ventricular Function ◽

Ventricular Function ◽

Left Ventricular Dysfunction ◽

Ventricular Dysfunction ◽

Contractile Function ◽

Weight Ratio ◽

Volume Overload ◽

Left Ventricular ◽

Mean Velocity

Left ventricular function in volume overload hypertrophy is controversial. In humans, chronic severe volume overload eventually results in left ventricular dysfunction; paradoxically, experimental volume overload hypertrophy has nearly always been associated with normal left ventricular function. However, in most cases, experimental volume overload hypertrophy has either been mild or only present for a short duration. To help resolve the issue of contractile function in volume overload hypertrophy, we examined ventricular function in a recently described model of severe chronic experimental mitral regurgitation. Left ventricular function was measured before and 3 mo after the creation of severe mitral regurgitation (averaged regurgitant fraction 0.64 +/- 0.04). At 3 mo end-diastolic volume had increased from 78 +/- 5 to 114 +/- 7 ml (P less than 0.01). Significant left ventricular hypertrophy had occurred with an increase in the left ventricular weight-to-body weight ratio from 3.84 +/- 0.2 to 5.22 +/- 0.2 (P less than 0.01). All indicators of left ventricular function (ejection fraction, the end ejection stress-volume relationship, this relationship corrected for eccentric hypertrophy, and mean velocity of circumferential fiber shortening at a common stress) were reduced at 3 mo. Our study produced 64% volume overload which was maintained for 3 mo at which time there was a 36% increase in left ventricular mass. This amount of volume overload of this duration produced significant left ventricular dysfunction.

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