scholarly journals Faculty Opinions recommendation of Nasal cannula apneic oxygenation prevents desaturation during endotracheal intubation: an integrative literature review.

Author(s):  
Jay Brodsky
2013 ◽  
Vol 29 (3) ◽  
pp. 197-202 ◽  
Author(s):  
Guilherme Lacerda de Toledo ◽  
Sebastião Cristian Bueno ◽  
Ricardo Alves Mesquita ◽  
Márcio Bruno Figueiredo Amaral

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e037964
Author(s):  
Shahan Waheed ◽  
Nazir Najeeb Kapadia ◽  
Muhammad Faisal Khan ◽  
Salima Mansoor Kerai ◽  
Ahmed Raheem ◽  
...  

IntroductionApnoeic oxygenation is a process of delivering continuous oxygen through nasal cannula during direct laryngoscopy. The oxygen that is delivered through these nasal cannulas is either low flow or high flow. Although the effectiveness of apnoeic oxygenation has been shown through systematic reviews and randomised controlled trials, a comparison of high-flow versus low-flow oxygen delivery has not been tested through a superiority study design. In this study we propose to assess the effectiveness of giving low-flow oxygen with head side elevation versus high-flow oxygen with head side elevation against the usual practice of care in which no oxygen is provided during direct laryngoscopy.Methods and analysisThis will be a three-arm study instituting a block randomisation technique with a sample size of 46 in each arm (see table 1). Due to the nature of the intervention, no blinding will be introduced. The primary outcomes will be lowest non-invasive oxygen saturation measurement during direct laryngoscopy and during the 2 min after the placement of the tube and the first pass success rate. The intervention constitutes head side elevation up to 30° for improving glottis visualisation together with low-flow or high-flow oxygen delivery through nasal cannula to increase safe apnoea time for participants undergoing endotracheal intubation. Primary analysis will be intention to treat.Ethics and disseminationThe study is approved by the Ethical Review Committee of Aga Khan University Hospital (2019-0726-2463). The project is an institution University Research Committee grant recipient 192 002ER-PK. The results of the study will be disseminated among participants, patient communities and healthcare professionals in the institution through seminars, presentations and emails. Further, the findings will be published in a highly accessed peer-reviewed medical journal and will be presented at both national and international conferences.Trial registration numberClinicalTrials.gov Registry (NCT04242537).


2019 ◽  
Vol 7 (S8) ◽  
pp. S380-S380 ◽  
Author(s):  
Jean-Damien Ricard ◽  
Baptiste Gaborieau ◽  
Juliette Bernier ◽  
Camille Le Breton ◽  
Jonathan Messika

2019 ◽  
Vol 20 (12) ◽  
pp. 1202-1203
Author(s):  
John J. McCloskey ◽  
Jamie McElrath Schwartz ◽  
Donald H. Shaffner

2012 ◽  
Vol 28 (1) ◽  
pp. 52-60 ◽  
Author(s):  
Brett Williams ◽  
Malcolm Boyle ◽  
Nicole Robertson ◽  
Coco Giddings

AbstractBackgroundHeart failure poses a significant burden of disease, resulting in 2,658 Australian deaths in 2008, and listed as an associated cause of death in a further 14,466 cases. Common in the hospital setting, continuous positive airway pressure (CPAP) therapy is a non-invasive ventilation technique used to prevent airway collapse and manage acute pulmonary edema (APO). In the hospital setting, CPAP has been known to decrease the need for endotracheal intubation in patients with APO. Therefore the objective of this literature review was to identify the effectiveness of CPAP therapy in the prehospital environment.MethodsA review of selected electronic medical databases (Cochrane, Medline, EMBASE, and CINAHL) was conducted from their commencement date through the end of May 2012. Inclusion criterion was any study type reporting the use of CPAP therapy in the prehospital environment, specifically in the treatment of heart failure and acute pulmonary edema. References of relevant articles were also reviewed.ResultsThe literature search located 1,253 articles, 12 of which met the inclusion criteria. The majority of studies found that the use of CPAP therapy in the prehospital environment is associated with reduced short-term mortality as well as reduced rates of endotracheal intubation. Continuous positive airway pressure therapy was also shown to improve patient vital signs during prehospital transport and reduce myocardial damage.DiscussionThe studies conducted of prehospital use of CPAP to manage APO have all demonstrated improvement in patient outcomes in the short term.ConclusionAvailable evidence suggests that the use of CPAP therapy in the prehospital environment may be beneficial to patients with acute pulmonary edema as it can potentially decrease the need for endotracheal intubation, improve vital signs during transport to hospital, and improve short-term mortality.WilliamsB, BoyleM, RobertsonN, GiddingsC. When pressure is positive: a literature review of the prehospital use of continuous positive airway pressure. Prehosp Disaster Med.2013;28(1):1-10.


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