Faculty Opinions recommendation of Fractional ablative carbon dioxide laser followed by topical sodium stibogluconate application: A treatment option for pediatric cutaneous leishmaniasis.

Background.Cutaneous leishmaniasis is an endemic disease in Iran. Pentavalent antimonial drugs have been the first line of therapy in cutaneous leishmaniasis for many years. However, the cure rate of these agents is still not favorable. This study was carried out to compare the efficacies of intralesional glucantime with topical trichloroacetic acid 50% (TCA 50%) + glucantime and fractional carbon dioxide laser + glucantime in the treatment of cutaneous leishmaniasis.Methods.A total of 90 patients were randomly divided into three groups of 30 to be treated with intralesional injection of glucantime, a combination of topical TCA 50% and glucantime, or a combination of fractional laser and glucantime. The overall clinical improvement and changes in sizes of lesions and scars were assessed and compared among three groups.Results.The mean duration of treatment was6.1±2.1weeks in all patients (range: 2–12 weeks) and6.8±1.7,5.2±1.0, and6.3±3.0weeks in glucantime, topical TCA plus glucantime, and fractional laser plus glucantime groups, respectively (P=0.011). Complete improvement was observed in 10 (38.5%), 27 (90%), and 20 (87%) patients of glucantime, glucantime + TCA, and glucantime + laser groups, respectively (P<0.001).Conclusion.Compared to glucantime alone, the combination of intralesional glucantime and TCA 50% or fractional CO2laser had significantly higher and faster cure rate in patients with cutaneous leishmaniasis.

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Carbon dioxide laser for the treatment of lupoid cutaneous leishmaniasis (LCL): A case series of 24 patients

Dermatology Online Journal ◽

10.5070/d35zb4v6kf ◽

2006 ◽

Vol 12 (2) ◽

Author(s):

Ali Asilian ◽

Fariba Iraji ◽

Hamid Reza Hedaiti ◽

Amir Hossein Siadat ◽

Shahla Enshaieh

Keyword(s):

Carbon Dioxide ◽

Cutaneous Leishmaniasis ◽

Carbon Dioxide Laser ◽

Case Series

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Endoscopic Management of Selected Early Vocal Cord Carcinoma

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348948509400607 ◽

1985 ◽

Vol 94 (6) ◽

pp. 560-564 ◽

Cited By ~ 77

Author(s):

Robert H. Ossoff ◽

George A. Sisson ◽

Stanley M. Shapshay

Keyword(s):

Carbon Dioxide ◽

Vocal Cord ◽

Treatment Option ◽

Carbon Dioxide Laser ◽

Excisional Biopsy ◽

Squamous Cell Carcinomas ◽

Endoscopic Management ◽

Partial Laryngectomy ◽

Glottic Carcinoma ◽

Early Glottic Carcinoma

Twenty-five previously untreated patients with selected early midcordal squamous cell carcinomas have been treated by endoscopic excisional biopsy with the carbon dioxide laser and followed for a minimum of 3 years. Twenty-four of the 25 patients are alive and free of disease, and one patient died of local and regional recurrence 2 years after attempted endoscopic excision followed by partial laryngectomy. Indications, contraindications, advantages, and complications associated with this treatment option for patients with early glottic carcinoma are discussed.

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Carbon Dioxide Laser Keratectomy as a Treatment Option for Equine Corneal Stromal Abscessation: A Comparison to Lamellar Keratectomy and Penetrating Keratoplasty

Journal of Equine Veterinary Science ◽

10.1016/j.jevs.2010.10.003 ◽

2010 ◽

Vol 30 (11) ◽

pp. 657-665 ◽

Cited By ~ 2

Author(s):

Natasha van Zyl ◽

Stephen G. Rayner

Keyword(s):

Carbon Dioxide ◽

Treatment Option ◽

Carbon Dioxide Laser ◽

Penetrating Keratoplasty

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Electron Cytochemical Study of Carbon Dioxide Laser Effect on Rhesus Monkey Cornea

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010005113x ◽

1974 ◽

Vol 32 ◽

pp. 224-225

Author(s):

K. C. Tsou ◽

J. Morris ◽

P. Shawaluk ◽

B. Stuck ◽

E. Beatrice

Keyword(s):

Carbon Dioxide ◽

Electron Microscope ◽

Rhesus Monkey ◽

Carbon Dioxide Laser ◽

Cytochemical Study ◽

Laser Effect

While much is known regarding the effect of lasers on the retina, little study has been done on the effect of lasers on cornea, because of the limitation of the size of the material. Using a combination of electron microscope and several newly developed cytochemical methods, the effect of laser can now be studied on eye for the purpose of correlating functional and morphological damage. The present paper illustrates such study with CO2 laser on Rhesus monkey.

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