Faculty Opinions recommendation of High frequency of inactivating tetraspanin CD37 mutations in diffuse large B-cell lymphoma at immune-privileged sites.

2019 ◽  
Author(s):  
Won Seog Kim
Keyword(s):  
B Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals High frequency of inactivating tetraspanin CD37 mutations in diffuse large B-cell lymphoma at immune-privileged sites

Blood ◽  
2019 ◽  
Vol 134 (12) ◽  
pp. 946-950 ◽  
Author(s):  
Suraya Elfrink ◽  
Charlotte M. de Winde ◽  
Michiel van den Brand ◽  
Madeleine Berendsen ◽  
Margaretha G. M. Roemer ◽  
...  
Keyword(s):  
B Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Loss Of Function ◽  
Large B Cell Lymphoma ◽  
Key Points ◽  
Surface Localization ◽  
Cell Surface Localization ◽  
Large B Cell

Key Points Loss-of-function mutations in CD37 occur predominantly in diffuse large B-cell lymphoma at immune-privileged sites. CD37-mutated lymphoma B cells show impaired CD37 cell-surface localization, which may have implications for anti-CD37 therapies.

scholarly journals High frequency of neurolymphomatosis as a relapse disease of intravascular large B-cell lymphoma

Cancer ◽  
2011 ◽  
Vol 117 (19) ◽  
pp. 4512-4521 ◽  
Author(s):  
Kosei Matsue ◽  
Brian Y. Hayama ◽  
Kan-Ichi Iwama ◽  
Takafumi Koyama ◽  
Hideaki Fujiwara ◽  
...  
Keyword(s):  
B Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Diffuse large B-cell lymphoma with concomitant c-MYC and BCL6 gene rearrangements with primary skin involvement: A case report and a review of literature

2017 ◽  
Vol 89 (7) ◽  
pp. 85-92 ◽  
Author(s):  
N G Gabeeva ◽  
D A Koroleva ◽  
A V Belyaeva ◽  
N G Chernova ◽  
L A Kuzmina ◽  
...  
Keyword(s):  
B Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Gene Rearrangements ◽  
Review Of Literature ◽  
Large B Cell Lymphoma ◽  
Double Hit Lymphoma ◽  
Resistance To Chemotherapy ◽  
Large B Cell

Double-hit lymphoma (DHL) is a rare aggressive B-cell lymphoma with concomitant c-MYC, BCL2 or BCL6 gene rearrangements, which is characterized by the high frequency of extranodal lesions and by resistance to chemotherapy. The median survival does not exceed 18 months in patients with this disease. The majority of DHL is represented by с-MYC/BCL2 cases. The combination of c-MYC/BCL6 occurs rarely (5—8%). The paper describes a case of DHL with concomitant c-MYC and BCL6 gene rearrangements, which mimics diffuse large B-cell lymphoma, leg-type.

scholarly journals High Frequency and Clinical Prognostic Value of MYD88 L265P Mutation in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg-Type

2014 ◽  
Vol 150 (11) ◽  
pp. 1173 ◽  
Author(s):  
Anne Pham-Ledard ◽  
Marie Beylot-Barry ◽  
Coralie Barbe ◽  
Marion Leduc ◽  
Tony Petrella ◽  
...  
Keyword(s):  
B Cell ◽  
High Frequency ◽  
Prognostic Value ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Myd88 L265p Mutation ◽  
Myd88 L265p ◽  
Large B Cell

High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice

2011 ◽  
Vol 89 (5) ◽  
pp. 493-504 ◽  
Author(s):  
Marzia Ognibene ◽  
Ottavia Barbieri ◽  
Cristina Vanni ◽  
Luca Mastracci ◽  
Simonetta Astigiano ◽  
...  
Keyword(s):  
B Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

High Frequency of Bone Marrow Involvement in Intravascular Large B-Cell Lymphoma

2016 ◽  
Vol 25 (2) ◽  
pp. 118-126 ◽  
Author(s):  
Jianchao Wang ◽  
Wenshuang Ding ◽  
Limin Gao ◽  
Wenqing Yao ◽  
Min Chen ◽  
...  
Keyword(s):  
Bone Marrow ◽  
B Cell ◽  
High Frequency ◽  
Cell Lymphoma ◽  
Bone Marrow Involvement ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell
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