Faculty Opinions recommendation of Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.

2021 ◽  
Author(s):  
Alvin M Matsumoto
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Advanced Prostate Cancer ◽  
Orally Active

scholarly journals A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

Cell ◽  
2018 ◽  
Vol 174 (2) ◽  
pp. 422-432.e13 ◽  
Author(s):  
David Y. Takeda ◽  
Sándor Spisák ◽  
Ji-Heui Seo ◽  
Connor Bell ◽  
Edward O’Connor ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Advanced Prostate Cancer

Abstract B14: Developing small-molecule inhibitors to the androgen receptor N-terminus domain for the treatment of advanced prostate cancer

2012 ◽  
Vol 72 (4 Supplement) ◽  
pp. B14-B14
Author(s):  
Marianne D. Sadar ◽  
Jae-Kyung Myung ◽  
Iain McEwan ◽  
Stephen Plymate ◽  
Raymond J. Andersen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Small Molecule ◽  
Advanced Prostate Cancer ◽  
Small Molecule Inhibitors ◽  
N Terminus

scholarly journals Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer

2019 ◽  
Vol 145 (2) ◽  
pp. 415-426 ◽  
Author(s):  
Qipeng Liu ◽  
Guangyu Wang ◽  
Qiaqia Li ◽  
Weihua Jiang ◽  
Jung‐Sun Kim ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Advanced Prostate Cancer ◽  
Polycomb Group ◽  
Polycomb Group Proteins
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