scholarly journals Clinico-Radiographic Analysis of Descending Necrotizing Mediastinitis with Deep Neck Infection

2021 ◽  
Vol 32 (2) ◽  
pp. 125-131
Author(s):  
Bo Young Kim ◽  
Young-Soo Chang ◽  
Kyoung Rai Cho
Keyword(s):  
Radiographic Analysis ◽  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection

Descending necrotizing mediastinitis from deep neck infection

2012 ◽  
Vol 270 (4) ◽  
pp. 1463-1466 ◽  
Author(s):  
Hajime Ishinaga ◽  
Kazuya Otsu ◽  
Hiroshi Sakaida ◽  
Tomotaka Miyamura ◽  
Satoshi Nakamura ◽  
...  
Keyword(s):  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection

Deep Neck Infection Accompanied by Descending Necrotizing Mediastinitis

2015 ◽  
Vol 26 (5) ◽  
pp. e464-e465 ◽  
Author(s):  
Muhammed Sedat Sakat ◽  
Enver Altaş ◽  
Bülent Aktan ◽  
Korhan Kiliç ◽  
Harun Üçüncü
Keyword(s):  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection

scholarly journals Less invasive management of deep neck infection and descending necrotizing mediastinitis

Medicine ◽  
2017 ◽  
Vol 96 (15) ◽  
pp. e6590 ◽  
Author(s):  
Dong Wei ◽  
Ling Bi ◽  
Huiyong Zhu ◽  
Jianfeng He ◽  
Huiming Wang
Keyword(s):  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection ◽  
Less Invasive ◽  
Invasive Management

scholarly journals Multidisciplinary treatment of deep neck infection associated with descending necrotizing mediastinitis: a single-centre experience

2019 ◽  
Vol 47 (12) ◽  
pp. 6027-6040 ◽  
Author(s):  
Chao Ma ◽  
Lian Zhou ◽  
Ji-Zhi Zhao ◽  
Run-Tai Lin ◽  
Tao Zhang ◽  
...  
Keyword(s):  
Thoracoscopic Surgery ◽  
Multidisciplinary Treatment ◽  
Multiple Organ ◽  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
College Hospital ◽  
Odontogenic Infections ◽  
Neck Infection ◽  
Medical College ◽  
Mediastinal Drainage

Objective Deep neck infection (DNI) associated with descending necrotizing mediastinitis (DNM) is a highly lethal condition. This retrospective review was performed to share our experience performing multidisciplinary management of DNI associated with DNM during a 7-year period. Methods We reviewed 16 patients who had been surgically treated for DNM at Peking Union Medical College Hospital from April 2010 to July 2017. The clinical outcomes were analysed to determine the most appropriate therapeutic strategy. Results Five women and 11 men were included in this study. Their mean age was 54.9 ± 14.3 years. DNM-associated infections most commonly occurred secondary to odontogenic infections (n = 10). Thirteen patients required tracheotomy because of tracheal compression. All patients underwent unilateral or bilateral cervicotomy. Six patients with DNM localized in the upper mediastinal space underwent transcervical mediastinal drainage, while 10 patients with DNM extending to the lower mediastinum were treated by cervicotomy and video-assisted thoracoscopic surgery. Three patients died of multiple organ failure. Conclusion Multidisciplinary treatment can achieve favourable outcomes in >80% of patients with DNM. Early diagnosis, proper airway management, and adequate surgical drainage are crucial for reducing mortality in patients with DNM, and minimally invasive procedures also play an important role.

scholarly journals A Case of Descending Necrotizing Mediastinitis Extending from Deep Neck Infection.

2001 ◽  
Vol 94 (12) ◽  
pp. 1117-1122
Author(s):  
Mitsuo TOMINAGA ◽  
Hayato MISAWA ◽  
Masaaki TERANISHI ◽  
Akihide Ito ◽  
Hideo HAYASHI ◽  
...  
Keyword(s):  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection

Approach for Drainage of Descending Necrotizing Mediastinitis on the Basis of the Extending Progression from Deep Neck Infection to Mediastinitis

2002 ◽  
Vol 53 (1) ◽  
pp. 112-116 ◽  
Author(s):  
Yoshihiro Moriwaki ◽  
Mitsugi Sugiyama ◽  
Goro Matsuda ◽  
Koichiro Date ◽  
Norihisa Karube ◽  
...  
Keyword(s):  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection

Descending Necrotizing Mediastinitis Resulting from Deep Neck Infection

2019 ◽  
Vol 70 (1) ◽  
pp. 9-16
Author(s):  
Akari Kimura ◽  
Shunsuke Miyamoto ◽  
Hiroshi Hosono ◽  
Taku Yamashita
Keyword(s):  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection

scholarly journals Management of Descending Necrotizing Mediastinitis, a Severe Complication of Deep Neck Infection, Based on Multidisciplinary Approaches and Departmental Co-Ordination

2022 ◽  
pp. 014556132110685
Author(s):  
Chia-Ying Ho ◽  
Shy-Chyi Chin ◽  
Shih-Lung Chen
Keyword(s):  
Mortality Rate ◽  
Treatment Protocol ◽  
Tertiary Hospital ◽  
Deep Neck Infection ◽  
Descending Necrotizing Mediastinitis ◽  
Neck Infection ◽  
Streptococcus Anginosus ◽  
Reactive Protein ◽  
Unit Management ◽  
Aggressive Interventions

Objectives Descending necrotizing mediastinitis (DNM) developing after deep neck infection (DNI) is a potentially lethal disease of the mediastinum with a mortality rate as high as 40% prior to the 1990s. No standard treatment protocol is available. Here, we present the outcomes of our multidisciplinary approaches for treating DNM originating from a DNI. Methods Between June 2016 and July 2021, there were 390 patients with DNIs admitting to our tertiary hospital. A total 21 patients with DNIs complicated with DNM were enrolled. The multidisciplinary approaches included establishment of airway security, appropriate surgery and antibiotics, extracorporeal membrane oxygenation, and intensive care unit management. The clinical variables were analyzed. Results Two patients died and 19 survived (mortality 9.5%). The patients who died had a higher mean C-reactive protein (CRP) level than did those who survived (420.0 ± 110.3 vs 221.8 ± 100.6 mg/L) (P = .038). The most common pathogens were Streptococcus constellatus and Streptococcus anginosus. From 2001 to 2021, the average mortality rate of studies enrolling more than 10 patients was 16.1%. Conclusion Multidisciplinary approaches, early comprehensive medical treatment, and co-ordination among departments significantly reduce mortality. Patients with severe inflammation and high CRP levels require intensive and aggressive interventions.

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