scholarly journals Infecção pelo Vírus da Zika Pode Causar Perda Auditiva Transitória em Adultos

2020 ◽  
Vol 1 (2) ◽  
pp. 36-37
Author(s):  
Viviane S. Boaventura ◽  
Eriko S. Vinhaes ◽  
Lislane Dias ◽  
Nilvano A. Andrade ◽  
Victor H. Bezerra ◽  
...  

Artigo original: Transient Hearing Loss in Adults Associated With Zika Virus Infection Eriko S. Vinhaes, Luciane A. Santos, Lislane Dias, Nilvano A. Andrade, Victor H. Bezerra, Anderson T. de Carvalho, Laise de Moraes, Daniele F. Henriques, Sasha R. Azar, Nikos Vasilakis, Albert I. Ko, Bruno B. Andrade, Isadora C. Siqueira, Ricardo Khouri and Viviane S. Boaventura. Clinical Infectious Diseases® 2017; 64(5): 675–7.

2017 ◽  
Vol 52 (9) ◽  
pp. 1345-1346 ◽  
Author(s):  
J Styczynski ◽  
J Hoek ◽  
N Knelange ◽  
M Mikulska ◽  
S Cesaro ◽  
...  

2019 ◽  
Vol 28 (1) ◽  
pp. 19-22 ◽  
Author(s):  
Mariana de Carvalho Leal ◽  
Danielle Seabra Ramos ◽  
Silvio S. Caldas Neto

2016 ◽  
pp. ciw770 ◽  
Author(s):  
Eriko S Vinhaes ◽  
Luciane A Santos ◽  
Lislane Dias ◽  
Nilvano A Andrade ◽  
Victor H Bezerra ◽  
...  

2019 ◽  
Vol 4 (2) ◽  
pp. 68 ◽  
Author(s):  
Matthew H. Collins

Zika virus is an emerging mosquito-borne flavivirus that recently caused a large epidemic in Latin America characterized by novel disease phenotypes, including Guillain-Barré syndrome, sexual transmission, and congenital anomalies, such as microcephaly. This epidemic, which was declared an international public health emergency by the World Health Organization, has highlighted shortcomings in our current understanding of, and preparation for, emerging infectious diseases in general, as well as challenges that are specific to Zika virus infection. Vaccine development for Zika virus has been a high priority of the public health response, and several candidates have shown promise in pre-clinical and early phase clinical trials. The optimal selection and implementation of imperfect serologic assays are among the crucial issues that must be addressed in order to advance Zika vaccine development. Here, I review key considerations for how best to incorporate into Zika vaccine trials the existing serologic tools, as well as those on the horizon. Beyond that, this discussion is relevant to other intervention strategies to combat Zika and likely other emerging infectious diseases.


2016 ◽  
Vol 147 (7) ◽  
pp. 300-305
Author(s):  
Lluís Valerio Sallent ◽  
Sílvia Roure Díez ◽  
Gema Fernández Rivas

2016 ◽  
Vol 65 (34) ◽  
pp. 917-919 ◽  
Author(s):  
Mariana C. Leal ◽  
Lilian F. Muniz ◽  
Tamires S.A. Ferreira ◽  
Cristiane M. Santos ◽  
Luciana C. Almeida ◽  
...  

Author(s):  
Liora Gonik ◽  
Amanda Tupinambá da Fonseca Oliveira ◽  
Paula Silva de Carvalho Chagas ◽  
Jaqueline da Silva Frônio

The known neurotropism of the Zika virus (ZikV) suggests that auditory organs and their neural pathways may be affected by prenatal Zika infections. Among the possible manifestations are audiological and language disorders, but so far, the data in the literature are inconclusive. Objective: To describe early and late hearing disorders in children with Congenital Zika Virus Infection (CZVI) and evaluate the language development of this population between 14 and 47 months of age and its possible correlation with the alterations found in auditory exams. Methods: Longitudinal, prospective, observational study of newborns born in Juiz de Fora and its macroregion with confirmed diagnosis of ZikV infection during pregnancy. Participants were examined from one to four years of age for hearing using the transient otoacoustic emissions (TOAE) test, immittance testing and brainstem auditory evoked potential (BAEP), and language using the Bayley Scales of Infant Development—Third Edition (Bayley III). Results: 15 participants were included; eight (53.33%) presented alterations in at least one of the hearing tests, one had an early loss (6%) of sensorineural origin, and seven (46.67%) had a poor language performance. In the three (20%) participants whose audiological exams were altered, there was language impairment, and two (13.33%) participants had extensive malformations in the central nervous system (CNS), presented language delay, and hearing exams were within normality. Conclusion: Infants and preschoolers with CZVI may present early neurosensory loss and late hearing loss with fluctuating character. Even if there were no significant association between the audiological exams results and the Bayley III performance, in the present sample, language development was below expectations for the age in the participants who had alterations in the three audiological exams, when there is early hearing loss or extensive lesions to the CNS. The results reinforce the importance of audiological examinations, especially the BAEP morphological and auditory threshold, in monitoring cases of CZVI until at least three years of age.


2019 ◽  
Vol 1 (1) ◽  
pp. 49-56
Author(s):  
Mariam M. Mirambo ◽  
Lucas Matemba ◽  
Mtebe Majigo ◽  
Stephen E. Mshana

Background: Zika virus infection during pregnancy has been recently associated with congenital microcephaly and other severe neural tube defects. However, the magnitude of confirmed cases and the scope of these anomalies have not been extensively documented. This review focuses on the magnitude of laboratory-confirmed congenital Zika virus cases among probable cases and describing the patterns of congenital anomalies allegedly caused by the Zika virus, information which will inform further research in this area. Methods: We conducted a literature search for English-language articles about congenital Zika virus infection using online electronic databases (PubMed/MEDLINE, POPLINE, Embase, Google Scholar, and Web of Knowledge). The search terms used were, “zika”, “pregnancy”, [year], “microcephaly”, “infants”, “children”, “neonates”, “foetuses”, “neural tube defect”, and “CNS manifestations” in different combinations. All articles reporting cases or case series between January 2015 and December 2016 were included. Data were entered into a Microsoft Excel database and analysed to obtain proportions of the confirmed cases and patterns of anomalies. Results: A total of 24 articles (11 case series, 9 case reports, and 4 others) were found to be eligible and included in this review. These articles reported 919 cases, with or without microcephaly, presumed to have congenital Zika virus infection. Of these cases, 884 (96.2%) had microcephaly. Of the 884 cases of microcephaly, 783 (88.6%) were tested for Zika virus infection, and 216 (27.6%; 95% confidence interval, 24.5% to 30.8%) were confirmed to be Zika virus-positive. In addition to microcephaly, other common abnormalities reported – out of 442 cases investigated – were calcifications of brain tissue (n=240, 54.3%), ventriculomegaly (n=93, 20.8%), cerebellar hypoplasia (n=52, 11.7%), and ocular manifestations (n=46, 10.4%). Conclusion: Based on the available literature, Zika virus infection during pregnancy might lead to a wide array of outcomes other than microcephaly. There is a need for more epidemiological studies in Zika-endemic areas, particularly in Africa, to ascertain the role of Zika virus in causing congenital neurological defects.


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