Although Latin American cities, on the whole, suffer from haphazard urbanism and environmental inequalities, concern around public health and nature has begun to emerge. Different ongoing initiatives relating to the ecosystem services of urban green attempt, among other things, to mitigate the effects of air pollution on respiratory problems. Green infrastructure across the subcontinent today offers opportunities—and represents challenges—for the implementation of policies promoting health and well-being which are emblematic of the urban revitalization process. This chapter shows some ongoing trends from Bogotá, Buenos Aires, and Curitiba, three representative cities in the region, that reflect the role of green spaces for the health and well-being of urban-dwellers in Latin American cities.