A STUDY TO EVALUATE THE EFFECT OF ANAEMIA IN TYPE-2 DIABETIC PATIENTS

2021 ◽  
pp. 117-119
Author(s):  
Radhika Maheshwari ◽  
Divya J. ◽  
J. Sahayaraj ◽  
Muthukrishnan R.
Keyword(s):  
Glycaemic Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Poor Glycaemic Control ◽  
The Poor ◽  
Microcytic Hypochromic Anaemia ◽  
Hypochromic Anaemia ◽  
Type 2 Diabetic ◽  
Hba1c Levels

Introduction: As the tribulation of diabetes escalates, developing countries like India is expected to be the diabetic capital in the world in coming years. Diabetes Mellitus progressively results in various complications including both microvascular and macrovascular disorders. The nephropathy undermines the renal production of erythropoietin, positively contributing to an increased anaemic framework. However, anaemia in type 2 diabetic patients is often untended. Aims And Objectives: • To correlate the levels of haemoglobin with the degree of glycaemic control (HbA1c>6.5% vs HbA1c<6.5%) • To determine the morphology and severity of anaemia in type 2 diabetic patients. • To know prevalence of other comorbidities as a result of anaemia and diabetes. Materials And Methods: A prospective observational study was conducted in 100 type 2 diabetic patients visiting the Out Patient Department in Acs Medical College and Hospital, Chennai. Haemoglobin and red cell indices were estimated. Comorbidities like hypertension, chronic kidney disease, arthritis and retinopathy were recorded. Peripheral blood smear examination was done using leishman's stain. Ion exchange chromatography was used to measure the HbA1c levels. Results: In the poor glycaemic control group, a signicant decrease in the haemoglobin levels was noted especially in females and elderly population. Microcytic Hypochromic Anaemia was the most prevalent which was of mild to moderate severity. Predominantly reduced iron stores in Microcytic Hypochromic Anaemia were attributed to increased HbA1c levels. The poor control of diabetes when associated with anaemia, were also found to have comorbidities like hypertension, chronic kidney disease, arthritis and retinopathy. Conclusion: To conclude, though anaemia is signicantly prevalent in diabetic patients, it is often neglected. In accordance with the study, poor glycaemic control is the result of increased glycation of haemoglobin A1c (HbA1c) due to reduced iron stores. Hence in diabetic patients, it would be benecial to assess haemoglobin levels often, for better quality of life

scholarly journals Comparison of Coagulation Profile in Type 2 Diabetic Patients with Good Glycaemic Control and Poor Glycaemic Control

2020 ◽  
Author(s):  
Binia Sherin ◽  
Bhuvanamha Devi Ramamurthy ◽  
Muthu Sudalaimuthu ◽  
Shivashekar Ganapathy
Keyword(s):  
Glycaemic Control ◽  
Bleeding Time ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Poor Glycaemic Control ◽  
Coagulation Profile ◽  
Good Glycaemic Control ◽  
Type 2 Diabetics ◽  
Type 2 Diabetic

Introduction: Diabetes Mellitus (DM) is a global health problem, characterised by high levels of glucose in blood with impairment of carbohydrate, fat and protein metabolism. Patients with DM have a high risk of developing atherothrombotic events. This leads to initiation and progression of microvascular and macrovascular complications. Aim: To compare the coagulation profile parameters in patients with Type 2 DM with good glycaemic control (Glycated Haemoglobin (HbA1c) <7) and poor glycaemic control (HbA1c ≥7) and to evaluate the association of coagulation profile and glycaemic control in diabetic patients. Materials and Methods: This study was conducted in a tertiary care hospital of Southern India on 84 patients among which 42 were Type 2 Diabetics with good glycaemic control and 42 were Type 2 Diabetics with poor glycaemic control. Blood samples were collected from the individuals chosen for the study and analysed for coagulation profile including Bleeding Time, Platelet Count, Prothrombin Time (PT), activated Partial Thromboplastin Time (aPTT), fibrinogen and d-Dimer. Statistical analysis was done by unpaired student’s t-test using SPSS 21.0. Results: In the present study, it was observed that Bleeding Time, aPTT and fibrinogen concentration were increased (statistically significant, p<0.05) in Type 2 Diabetics with poor glycaemic control when compared with Type 2 Diabetics with good glycaemic control. No significant changes were noted in Platelet Count, PT and d-Dimer among the two study groups. Conclusion: The alteration in coagulation profile of Type 2 Diabetic people has shown that hyperglycaemia leads to abnormalities in the coagulation and Type 2 Diabetic patients with poor glycaemic control are at high risk for developing atherothrombotic and haemorrhagic events. So, evaluation of coagulation profile in diabetic patients may help the clinicians in early intervention to prevent the initiation of microvascular and macrovascular disease at the earliest.

Proportion of type 2 diabetic patients achieving treatment goals and the survey of patient’s attitude towards insulin initiation in patients with inadequate glycaemic control with oral anti-diabetic drugs

2020 ◽  
Vol 16 ◽  
Author(s):  
Shivashankara Bhat ◽  
Mukta Chowta ◽  
Nithyananda Chowta ◽  
Rajeshwari Shastry ◽  
Priyanka Kamath
Keyword(s):  
Glycaemic Control ◽  
Diabetic Patients ◽  
Treatment Goals ◽  
Insulin Initiation ◽  
Type 2 Diabetic Patients ◽  
Number Of Patients ◽  
Patient’S Perception ◽  
Hba1c Target ◽  
Type 2 Diabetic

Background: Type 2 diabetic patients often require insulin therapy for better glycaemic control. However, many of these patients do not receive insulin or do not receive it in a timely manner. Objective: The study was planned to assess the proportion of type 2 diabetic patients attaining treatment goals as per the ADA 2018 guidelines. In addition, patient’s perception on insulin therapy assessed and compared between insulin naïve and insulin initiated type 2 diabetic patients. Methods: The study was conducted in type 2 diabetic patients. Data on their demographics, medical history, duration of diabetes, history of diabetes related complications, the current antidiabetic medication received, most recent glycaemic parameters were noted. Patient’s perception on insulin initiation was recorded through structured interview. Results: A total of 129 patients were included in the study. Around 76.7% patients achieved HbA1c target (<7%). Duration of the disease is much higher in patients who did not meet the HBA1c target. A good number of patients felt that insulin injection would be physically painful (56.5%). Majority of the patients also felt that insulin will make their life less flexible (64.8%). Many patients are having the opinion that insulin is required for life long (73.2%). More number of patients on insulin agreed with the statement ‘Leads to good short-term outcomes as well as long-term benefits’ compared to insulin naïve patients. Conclusion: The results highlight that the proportion of patients achieving recommended glycaemic target is not satisfactory. Many patients who are inadequately controlled with oral antidiabetic drugs were reluctant to initiate insulin.

Alexithymia, more than depression, influences glycaemic control of type 2 diabetic patients

2015 ◽  
Vol 38 (6) ◽  
pp. 653-660 ◽  
Author(s):  
A. Luca ◽  
M. Luca ◽  
M. Di Mauro ◽  
F. Palermo ◽  
F. Rampulla ◽  
...  
Keyword(s):  
Glycaemic Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

The relative effect of self-management practices on glycaemic control in type 2 diabetic patients in Mexico

2006 ◽  
Vol 2 (2) ◽  
pp. 77-85 ◽  
Author(s):  
Javier E. Garcia de Alba Garcia ◽  
Florence J. Dallo ◽  
Ana L. Salcedo Rocha ◽  
Cecilia Colunga Rodriguez ◽  
Noe Perez ◽  
...  
Keyword(s):  
Glycaemic Control ◽  
Management Practices ◽  
Relative Effect ◽  
Self Management ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic
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