Removing the Breast from the Body, Cryoectomy or Cryopreservation of Tumors Preserve Breast Size, Reduce the Risk of Infection and Prevent Scarring

Unprecedented studies have shown that slow-growing breast cancers can be treated with highly targeted tumor cryopreservation technology without the need for surgery. Experiments show that this method is effective in women with low-risk breast cancer over the age of 60. Cryoablation is a solution that eliminates breast tumors safely, quickly and painlessly or without the need for surgery. Takes. This method exposes the patient's tissues to severe cold to remove them without the need for anesthesia in the clinic. The new study, which involved about 200 women, found that after eliminating low-risk breast cancer, patients were left without cancer for three years. This treatment can be used to treat cancers of the bone, kidney, prostate and other types. Unlike lumpectomy or mastectomy, which involves removing the breast from the body, cryoectomy or cryopreservation of tumors preserve breast size, reduce the risk of infection and prevent scarring, and allow patients to function normally quickly, the researchers said. Resume yourself. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management

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Cryoablation and Cryolocalization in the Prevention, Prognosis, Diagnosis, Imaging, Screening, Treatment and Management of Breast Cancer

10.36811/jca.2021.110024 ◽

2021 ◽

pp. 592-633

Author(s):

Elena Locci ◽

Silvia Raymond

Keyword(s):

Breast Cancer ◽

The Body ◽

Low Risk ◽

Breast Size ◽

Breast Cancers ◽

Risk Of Infection ◽

Breast Cancer Patients ◽

Keywords Cancer ◽

Slow Growing ◽

Risk Breast Cancer

Unprecedented studies have shown that slow-growing breast cancers can be treated with highly targeted tumor cryopreservation technology without the need for surgery. Experiments show that this method is effective in women with low-risk breast cancer over the age of 60. Cryoablation is a solution that eliminates breast tumors safely, quickly and painlessly or without the need for surgery. Takes. This method exposes the patient's tissues to severe cold to remove them without the need for anesthesia in the clinic. The new study, which involved about 200 women, found that after eliminating low-risk breast cancer, patients were left without cancer for three years. This treatment can be used to treat cancers of the bone, kidney, prostate and other types. Unlike lumpectomy or mastectomy, which involves removing the breast from the body, cryoectomy or cryopreservation of tumors preserve breast size, reduce the risk of infection and prevent scarring, and allow patients to function normally quickly, the researchers said. Resume yourself. Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management

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Changes in peripheral immune cells after intraoperative radiation therapy in low-risk breast cancer

Journal of Radiation Research ◽

10.1093/jrr/rraa083 ◽

2020 ◽

Vol 62 (1) ◽

pp. 110-118

Author(s):

Isabel Linares-Galiana ◽

Miguel Angel Berenguer-Frances ◽

Rut Cañas-Cortés ◽

Monica Pujol-Canadell ◽

Silvia Comas-Antón ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Single Dose ◽

Cancer Patients ◽

Antitumor Immunity ◽

Low Risk ◽

Intraoperative Radiation Therapy ◽

Breast Cancer Patients ◽

Intraoperative Radiation ◽

Risk Breast Cancer

Abstract A detailed understanding of the interactions and the best dose-fractionation scheme of radiation to maximize antitumor immunity have not been fully established. In this study, the effect on the host immune system of a single dose of 20 Gy through intraoperative radiation therapy (IORT) on the surgical bed in low-risk breast cancer patients undergoing conserving breast cancer has been assessed. Peripheral blood samples from 13 patients were collected preoperatively and at 48 h and 3 and 10 weeks after the administration of radiation. We performed a flow cytometry analysis for lymphocyte subpopulations, natural killer cells (NK), regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSCs). We observed that the subpopulation of NK CD56+high CD16+ increased significantly at 3 weeks after IORT (0.30–0.42%, P < 0.001), while no changes were found in immunosuppressive profile, CD4+CD25+Foxp3+Helios+ Treg cells, granulocytic MDSCs (G-MDSCs) and monocytic MDSCs (Mo-MDSCs). A single dose of IORT may be an effective approach to improve antitumor immunity based on the increase in NK cells and the non-stimulation of immunosuppressive cells involved in immune escape. These findings support future combinations of IORT with immunotherapy, if they are confirmed in a large cohort of breast cancer patients.

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