keywords cancer
Recently Published Documents


TOTAL DOCUMENTS

87
(FIVE YEARS 74)

H-INDEX

1
(FIVE YEARS 1)

2021 ◽  
pp. 383-423
Author(s):  
Alireza Heidari ◽  
Ricardo Gobato ◽  
Abhijit Mitra

According to the results of a global phase 2 clinical trial, the new drug sotorasib reduces tumor size and promises to improve and increase survival in patients with lung tumors caused by specific DNA mutations. It is designed to counteract the effects of mutations that are seen in about 13% of patients with non-small cell lung adenocarcinoma (a common type of lung cancer). The Food and Drug Administration (FDA) on May 28 approved the drug as a targeted treatment for patients with small cell lung cancer whose tumors express a specific mutation called G12C in the KRAS gene. Small cell lung cancer accounts for more than 80% of lung cancers. More than 200,000 new cases of non-small cell lung cancer are diagnosed in the United States each year. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 825-867
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 624-664
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

Early and timely diagnosis of any disease, especially cancer; Increases the chances of treatment and recovery; Therefore, it is better to be aware of the symptoms of lung cancer in the continuation of this article. It is advisable to first get acquainted with the causes of lung cancer so that we can assess our situation. The most important causes of lung cancer are smoking and other tobacco products, genetic mutations and family history. Second- and third-hand cigarette smoke and environmental pollutants such as air pollution also play a role in the development of this cancer. Of course, the role of colorless gas and the smell of radon and occupational exposure to compounds such as asbestos, arsenic and nickel should not be overlooked. Once we know the causes of lung cancer, we can look at its symptoms in our body. The most important symptoms of lung cancer are persistent cough, fatigue and lack of energy, and unexplained weight loss. Coughs such as coughing up blood and shortness of breath are other important symptoms of this cancer. Stomach, back, shoulder, and chest pain, as well as pain in the head, neck, and jaw, are other symptoms. In order to prevent lung cancer, special points should be considered, which we will mention in the following. The main advice is to avoid smoking and also not to be exposed to secondhand smoke; Therefore, avoid using any tobacco and quit if you smoke. People who are in work situations and exposure to things like asbestos should try to minimize this exposure and use breathing masks. Opening windows and covering cracks in walls and floors is important to reduce radon concentrations. It is recommended to eat more vegetables and fruits, especially cabbage, orange vegetables and garlic. It is important to note that awareness of the symptoms of the disease is very important for early diagnosis and thus increase the chances of treatment. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 584-625
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

Unprecedented studies have shown that slow-growing breast cancers can be treated with highly targeted tumor cryopreservation technology without the need for surgery. Experiments show that this method is effective in women with low-risk breast cancer over the age of 60. Cryoablation is a solution that eliminates breast tumors safely, quickly and painlessly or without the need for surgery. Takes. This method exposes the patient's tissues to severe cold to remove them without the need for anesthesia in the clinic. The new study, which involved about 200 women, found that after eliminating low-risk breast cancer, patients were left without cancer for three years. This treatment can be used to treat cancers of the bone, kidney, prostate and other types. Unlike lumpectomy or mastectomy, which involves removing the breast from the body, cryoectomy or cryopreservation of tumors preserve breast size, reduce the risk of infection and prevent scarring, and allow patients to function normally quickly, the researchers said. Resume yourself. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 141-181
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

In recent years, immunotherapy has revolutionized the treatment of cancer; However, inflammatory reactions in healthy tissues often have side effects that can be serious and lead to permanent discontinuation of treatment. This toxicity is not yet well understood and is a major obstacle to the use of immunotherapy. When the immune system is so severely activated, the resulting inflammatory reaction can have detrimental effects and sometimes serious damage to healthy tissue. We wanted to know if there was a difference between an optimal immune response that aims to kill cancer and an unwanted response that could affect healthy tissue. Identifying the distinctive elements between these two immune responses allows the development of new, more effective and less toxic therapeutic approaches. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 782-824
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

Using samples of small cell lung tumors, a research team led by biologist Dr. Raymond discovered two new ways to induce tumor cell death. By activating ferroptosis, one of two subtypes of tumor cells can be targeted: first, iron-dependent cell death due to oxidative stress, and second, oxidative stress. Therefore, cell death can also be induced in a different way. Both types of cell death must be caused by drugs at the same time to eliminate the majority of the tumor mass. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 261-300
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

Understanding cellular metabolism (how cells use energy) can be key in treating a wide range of diseases, including vascular disease and cancer. Although many techniques can measure these processes in tens of thousands of cells, researchers have not been able to measure them at the single-cell level. Researchers have used a genetically encoded biosensor with artificial intelligence to measure glycolysis. (Process of converting glucose to energy, single endothelial cells, blood vessel cells). Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 742-781
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

Researchers have discovered an enzyme that inhibits the growth of cancer cells by stimulating proteins. In this study, the ability of each human cell to divide into two parts is discussed. For each division, a cell must follow certain steps, most of which are amplified by proteins called cyclins. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 503-543
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

When it comes to the microbiome, people usually think of the gut, but there is also the breast microbiome, and its role in the health and risk of breast cancer is not fully understood. A microbiome is a collection of microorganisms that live in a specific environment in the body. Diet can affect the breast microbiome, which shows that like the gut microbiome, breast microbiomes can respond to diet. New research now shows that diet, including fish oil supplements, can alter not only the breast microbiome but also its cancerous tumors. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


2021 ◽  
pp. 342-380
Author(s):  
Ricardo Gobato ◽  
Abhijit Mitra

In this recent study, DNA data from 900 patients with colorectal cancer were reviewed. Analysis of the data showed a distinct mutation signature, a pattern that had never been identified before but indicated a type of DNA damage called "alkylation." Red meat contains chemicals that can cause alkylation. High levels of tumor alkylation damage are seen only in patients who consume an average of more than 150 grams of meat per day, roughly equivalent to two or more meals. On the other hand, a group of researchers in 2019 in a controversial conclusion stated that they do not have much confidence in reducing deaths from colon cancer by avoiding red meat. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management


Sign in / Sign up

Export Citation Format

Share Document