scholarly journals Adipose Tissue-Derived Mesenchymal Stem Cells Induce Expansion of Interleukin-10-Producing Regulatory B Cells and Ameliorate Autoimmunity in a Murine Model of Systemic Lupus Erythematosus

2015 ◽  
Vol 24 (11) ◽  
pp. 2367-2377 ◽  
Author(s):  
Min-Jung Park ◽  
Seung-Ki Kwok ◽  
Sung-Hee Lee ◽  
Eun-Kyung Kim ◽  
Sung-Hwan Park ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Adipose Tissue ◽  
B Cells ◽  
Murine Model ◽  
Lupus Erythematosus ◽  
Interleukin 10 ◽  
Regulatory B Cells ◽  
Systemic Lupus

Stem cell transplantation: progress in Asia

Lupus ◽  
2010 ◽  
Vol 19 (12) ◽  
pp. 1468-1473 ◽  
Author(s):  
L. Sun
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Hematopoietic Stem ◽  
The Past ◽  
Complex Autoimmune Disease ◽  
Significant Mortality

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multiorgan involvement and high mortality, which was reduced because of the most widely and classically used immunosuppressive therapies. However, some patients continue to have significant mortality. So a shift in the approach to the treatment of SLE is needed. In the past decade, most transplants have been performed in the treatment of SLE with allogeneic or autologous hematopoietic stem cells and currently emerging mesenchymal stem cells. There are some important differences between the two procedures.

Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus

Lupus ◽  
2010 ◽  
Vol 19 (7) ◽  
pp. 850-859 ◽  
Author(s):  
Y. Nie ◽  
C. Lau ◽  
A. Lie ◽  
G. Chan ◽  
M. Mok
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Lupus Erythematosus ◽  
Systemic Lupus
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