Reducing the Risk in Controlled Drug Release by Using Tannic Acid in Liposomal Formulations
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One of the main challenges in designing a release system is the possibility to control the release rate in order to maintain it at a constant value below a defined limit, to avoid exceeding the toxicity threshold. We propose a method of overcoming this difficulty by introducing the drug into liposomes, prior to its inclusion in the hydrogel. Furthermore, a natural cross linker (as is tannic acid) is used, instead of the toxic cross linkers commonly used, thus reducing the toxicity of the release system as a whole.
2019 ◽
Vol 175
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pp. 239-247
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2017 ◽
Vol 532
(1)
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pp. 365-373
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2020 ◽
Vol 163
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pp. 824-832
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2005 ◽
Vol 35
(3)
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pp. 157-163
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2008 ◽
Vol 317
(2)
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pp. 477-484
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