scholarly journals Patient characteristics with high or low blood urea nitrogen in upper gastrointestinal bleeding

2015 ◽  
Vol 21 (24) ◽  
pp. 7500 ◽  
Author(s):  
Minoru Tomizawa
Keyword(s):  
Gastrointestinal Bleeding ◽  
Blood Urea Nitrogen ◽  
Upper Gastrointestinal Bleeding ◽  
Patient Characteristics ◽  
Urea Nitrogen ◽  
Upper Gastrointestinal

scholarly journals Does Blood Urea Nitrogen Level Predict Severity and High-Risk Endoscopic Lesions in Patients with Nonvariceal Upper Gastrointestinal Bleeding?

2008 ◽  
Vol 22 (4) ◽  
pp. 399-403 ◽  
Author(s):  
Khalid Al-Naamani ◽  
Nabil Alzadjali ◽  
Alan N Barkun ◽  
Carlo A Fallone
Keyword(s):  
High Risk ◽  
Blood Transfusion ◽  
Gastrointestinal Bleeding ◽  
Blood Urea Nitrogen ◽  
Upper Gastrointestinal Bleeding ◽  
Univariate Analysis ◽  
Urea Nitrogen ◽  
Icu Admission ◽  
The Mean ◽  
Upper Gastrointestinal

BACKGROUND: Nonvariceal upper gastrointestinal bleeding (UGIB) is a serious medical condition requiring prompt resuscitation and early endoscopic therapy in those with high-risk endoscopic lesions (HRLs). There are little or no data correlating sole blood urea nitrogen (BUN) level with the severity of nonvariceal UGIB or the presence of HRLs in the adult population.OBJECTIVES: To determine if the BUN level on presentation correlates with parameters of severity of UGIB (need for blood transfusion or intensive care unit [ICU] admission) or to the subsequent finding of HRL, and in so doing identify patients who will require early endoscopic intervention.METHODS: The Canadian Registry of patients with Upper Gastrointestinal Bleeding undergoing Endoscopy was used to identify patients enrolled from the McGill University Health Centre (Montreal, Quebec) who presented with or developed acute nonvariceal UGIB while admitted. All comparisons were performed using Student’sttest or Wilcoxon’s signed rank test, as appropriate. Logistic regression modelling using a stepwise method was performed to identify independent predictors of severe nonvariceal UGIB and HRL.RESULTS: Two hundred nine patients were enrolled in the study. The mean age was 67±18 years and 59.8% were male. The mean BUN level was 13.4±9.4 mmol/L. Univariate analysis demonstrated that the BUN level was a significant predictor of ICU admission (BUN 14.7±10.4 mmol/L versus 12.0±8.0 mmol/L, P=0.035). However, when adjusted for systolic blood pressure, BUN level became a weaker predictor of ICU admission, just failing to achieve statistical significance (OR 1.03, 95% CI 1.00 to 1.06; P=0.08). Univariate analysis also demonstrated that BUN level was not a statistically significant predictor of blood transfusion requirement (BUN 14.1±10.6 mmol/L versus 13.6±8.6 mmol/L, P=0.508), nor of HRL (BUN 14.2±10.7 mmol/L versus 12.9±8.6 mmol/L, P=0.605).CONCLUSION: In patients with nonvariceal UGIB, the BUN level at initial presentation is a weak predictor of the severity of UGIB as defined by ICU admission, but is not helpful in identifying patients with a HRL.

Blood urea nitrogen titration in upper gastrointestinal bleeding: Relationship with ulcer stigmata and rebleeding

2006 ◽  
Vol 38 ◽  
pp. S71-S72
Author(s):  
G.L. Milandri ◽  
A. Graziani ◽  
G. Nicolini ◽  
G. Bisulli ◽  
A. Castagnoli ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Blood Urea Nitrogen ◽  
Upper Gastrointestinal Bleeding ◽  
Urea Nitrogen ◽  
Upper Gastrointestinal

The association between blood urea nitrogen to creatinine ratio and mortality in patients with upper gastrointestinal bleeding

2018 ◽  
Vol 19 (4) ◽  
pp. 143-147 ◽  
Author(s):  
Kai-Hsiang Wu ◽  
Hsin-An Shih ◽  
Ming-Szu Hung ◽  
Cheng-Ting Hsiao ◽  
Yi-Chuan Chen
Keyword(s):  
Gastrointestinal Bleeding ◽  
Blood Urea Nitrogen ◽  
Upper Gastrointestinal Bleeding ◽  
Creatinine Ratio ◽  
Urea Nitrogen ◽  
Upper Gastrointestinal

Towards personalised management for non-variceal upper gastrointestinal bleeding

Gut ◽  
2021 ◽  
pp. gutjnl-2020-323846
Author(s):  
Joseph J Y Sung ◽  
Loren Laine ◽  
Ernst J Kuipers ◽  
Alan N Barkun
Keyword(s):  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Point Of Care ◽  
Management Strategies ◽  
Patient Characteristics ◽  
Professional Societies ◽  
Assessment And Treatment ◽  
Three Stages ◽  
Endoscopic Assessment ◽  
Upper Gastrointestinal

Guidelines from national and international professional societies on upper gastrointestinal bleeding highlight the important clinical issues but do not always identify specific management strategies pertaining to individual patients. Optimal treatment should consider the personal needs of an individual patient and the pertinent resources and experience available at the point of care. This article integrates international guidelines and consensus into three stages of management: pre-endoscopic assessment and treatment, endoscopic evaluation and haemostasis and postendoscopic management. We emphasise the need for personalised management strategies based on patient characteristics, nature of bleeding lesions and the clinical setting including available resources.

scholarly journals In-Hospital Nonvariceal Upper Gastrointestinal Bleeding following Cardiac Surgery: Patient Characteristics, Endoscopic Lesions and Prognosis

Ulcers ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Marcos Amorim ◽  
Alan N. Barkun ◽  
Martin Larocque ◽  
Karl Herba ◽  
Benoit DeVarennes ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cardiac Surgery ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Patient Characteristics ◽  
Hemodynamic Instability ◽  
Predictors Of Outcome ◽  
Surgery Patient ◽  
Endoscopic Characteristics ◽  
Upper Gastrointestinal

Background. Nonvariceal upper gastrointestinal bleeding (NVUGIB) can occur following cardiac surgery, with sparse contemporary data on patient characteristics and predictors of outcome in this setting. Aim. To describe the clinical and endoscopic characteristics of patients with NVUGIB following cardiac surgery and characterize predictors of outcome. Methods. Retrospective review of 131 consecutive patients with NVUGIB following cardiac surgery from 2002 to 2005. Demographic characteristics, therapeutic management, and predictors of outcomes were determined. Results. 69.5% were male, mean age: 68.8 ± 10.2 yrs, mean Parsonnet score: 24.6 ± 14.2. Commonest symptoms included melena (59.4%) or coffee ground emesis (25.8%). In-hospital medications included ASA (88.5%), heparin (95.4%, low molecular weight 6.9%), coumadin (48.1%), clopidogrel (22.9%), and NSAIDS (42%). Initial hemodynamic instability was noted in 47.1%. Associated laboratory results included hematocrit 26 ± 6, platelets 243 ± 133 109/L, INR 1.7 ± 1.6, and PTT 53.3 ± 35.6 s. Endoscopic evaluation (122 patients) yielded ulcers (85.5%) with high-risk lesions in 45.5%. Ulcers were located principally in the stomach (22.5%) or duodenum (45.9%). Many patients had more than one lesion, including esophagitis (28.7%) or erosions (26.8%). 48.8% received endoscopic therapy. Mean lengths of intensive care unit and overall stays were 10.4 ± 18.4 and 39.4 ± 46.9 days, respectively. Overall mortality was 19.1%. Only mechanical ventilation under 48 hours predicted mortality (O.R = 0.11; 95% CI = 0.04−0.34). Conclusions. This contemporary cohort of consecutive patients with NVUGIB following cardiac surgery bled most often from ulcers or esophagitis; many had multiple lesions. ICU and total hospital stays as well as mortality were significant. Mechanical ventilation for under 48 hours was associated with improved survival.

Patient Characteristics, Etiology, and Outcomes of Patients Admitted with Upper Gastrointestinal Bleeding

2016 ◽  
Vol 111 ◽  
pp. S164-S166
Author(s):  
May Olayan ◽  
Haider Al Taii ◽  
Abeer Mohideen ◽  
Manal Mahmoud ◽  
Gauraf Kistangari
Keyword(s):  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Patient Characteristics ◽  
Upper Gastrointestinal

Non Variceal Upper Gastrointestinal Bleeding (UGIB) Following Cardiac Surgery: Patient Characteristics, Endoscopic Lesions and Prognosis

2007 ◽  
Vol 65 (5) ◽  
pp. AB158
Author(s):  
Marcos Amorim ◽  
Alan N. Barkun ◽  
Martin Larocque ◽  
Karl Herba ◽  
Benoit Devarennes ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Patient Characteristics ◽  
Cardiac Surgery Patient ◽  
Surgery Patient ◽  
Upper Gastrointestinal
Sign in / Sign up

Export Citation Format

Share Document